Allelic polymorphism of 13 rare blood group systems in Li Ethnic Group in Hainan
10.13303/j.cjbt.issn.1004-549x.2021.09.009
- VernacularTitle:海南黎族人群13个稀有血型系统等位基因多态性的研究
- Author:
Xiaoling FU
1
;
Xingquan CAI
2
;
Shiping YANG
2
;
Xingdan ZHAO
1
;
Aihan WENG
1
;
Lan XIA
2
Author Information
1. Department of Blood Transfusion, Hainan Women and Children′s Medical Center, Haikou 570311, China
2. Hainan General Hospital
- Publication Type:Journal Article
- Keywords:
rare blood group;
gene polymorphism;
gene frequency;
rare blood group database;
Li ethnic group
- From:
Chinese Journal of Blood Transfusion
2021;34(9):970-974
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To detect alleles of rare blood group systems of red blood cells (RBC) of Duffy, Diego, Kidd, Dombrock, MNS, Lutheran, Kell, Colton, Scianna, YT, Knops, Indian and Vel of Li Ethnic Group in Hainan, so as to investigate the distribution characteristics of rare blood group alleles and provide references for safe blood transfusion. 【Methods】 The genotypes of 13 rare blood group systems in 300 Li people in Hainan were analyzed by PCR-SSP, and the gene frequency was analyzed . 【Results】 The allele frequencies of Duffy, Diego, Kidd, Dombrock, MNS, and Lutheran blood group systems of 300 Li people were as follows: Duffy: Fya=0.958 3, Fyb=0.041 7; Diego: Dia=0.066 7, Dib=0.933 3; Kidd: Jka=0.450 0, Jkb=0.550 0; Dombrock: Doa=0.101 7, Dob=0.898 3; MNS: M=0.818 3, N=0.181 7, S=0.028 3, s=0.971 7, Mur+ =0.576 7; Lutheran: Aua=0.835 0, Aub=0.165 0. The antigen genes of Kell, Colton, Scianna, Yt, Knops, Indian, Vel blood group systems were not polymorphic, and the genetypes were kk, CoaCoa, Sc1Sc1, YtaYta, KnaKna, InbInb and Vel+, respectively. 【Conclusion】 The allele frequencies of Duffy, Diego, Kidd, Dombrock, MNS and Lutheran blood group systems of Li ethnic group in Hainan were polymorphic, while the allele frequencies of Kell, Scianna, Yt, Knops, Colton, Indian and Vel blood group systems were monomorphic.
