Results analysis of unexpected antibody screening for blood donors and cost comparison of two detection modes
10.13303/j.cjbt.issn.1004-549x.2022.03.024
- VernacularTitle:全面开展献血者意外抗体筛查结果分析和不同检测模式成本比较
- Author:
Liqin HUANG
1
;
Lifeng WU
1
;
Tong LI
1
;
Ran LI
1
;
Heng LIU
1
;
Dandan DU
1
;
Yunlong CHEN
1
;
Xuezheng ZENG
1
;
Jinfeng ZENG
1
Author Information
1. Shenzhen Blood Centre, Shenzhen 518025, China
- Publication Type:Journal Article
- Keywords:
blood donor;
unexpected antibody;
blood screening;
cost comparison
- From:
Chinese Journal of Blood Transfusion
2022;35(3):324-327
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To establish a routine screening method for unexpected antibodies of blood donors, analyze the results of centralized screening for unexpected antibody of blood donors in the blood center, and compare the cost of centralized and decentralized screening modes. 【Methods】 A total of 35 591 blood donors were screened for unexpected antibodies from March 31, 2021 to July 31, 2021, using microcolumn gel method. Unexpected antibody screening reactive samples were further confirmed by the Transfusion Research Institute of Shenzhen Blood Center, and the demographic characteristics were further determined through the analysis of unexpected antibody positive population. The direct cost and indirect cost of centralized and decentralized unexpected antibody screening mode were compared. 【Results】 Forty unexpected antibody positive samples were confirmed in Shenzhen, with the positive rate at 0.11%(40/35 591), among which MNS, Rh and Lewis system accounted for 35% (14/40), 32.5% (13/40) and 17.5% (7/40), respectively. Males and females accounted for 45% (18/40) and 55% (22/40), respectively (P<0.01). No significant difference was noticed by age and repeated-donor or not (P>0.05). Unexpected antibody screening in a centralized way saved about 1.16 million yuan per year. 【Conclusion】 It is necessary to carry out unexpected antibody screening for all blood donors, and centralized screening is more economical than decentralized screening.
