How apheresis donation effects peripheral blood parameters in plateletpheresis donors: Propensity Score Matching method
10.13303/j.cjbt.issn.1004-549x.2021.10.021
- VernacularTitle:血小板捐献者外周血参数在血小板捐献前后的变化:1项倾向性匹配方法分析研究
- Author:
Fanfan FENG
1
;
Xuecheng DENG
1
;
Shijie LI
1
;
Guiyun XIE
1
;
Lei WU
1
;
Yangfan DENG
1
;
Jinyan CHEN
1
;
Huaqin LIANG
1
Author Information
1. Guangzhou Blood Center, Guangzhou Key Laboratory of Medical, Guangzhou 510095, China
- Publication Type:Journal Article
- Keywords:
plateletpheresis;
peripheral parameters;
Propensity Score Matching
- From:
Chinese Journal of Blood Transfusion
2021;34(10):1141-1144
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To investigate the changes of platelet, white blood cell, red blood cell counts, Hb and PCV before and after plateletpheresis donation. 【Methods】 10 444 platelet donors who donated platelet from Aug 1, 2019 to Jul 31, 2020 were selected as subjects, among which first-time donors were selected as control group and donors who donated twice or more as donation group. After matching gender and age using Propensity Score Matching method in the two groups, the changes of platelet, white blood cell, red blood cell counts, Hb and PCV of platelet blood donors were compared by t test. 【Results】 There were a slight increase in Plt (t=-6.651, P<0.05), a decrease in WBC (t=2.312, P<0.05), a decrease in hemoglobin(t=4.643, P<0.05), and no change in RBC (t=1.439, P>0.05) and in PCV (t=0.030, P>0.05) after plateletpheresis donation. 【Conclusion】 Plateletpheresis donation has an effect on some peripheral blood parameters, but within the normal reference range.