The Progress of Red Blood Cells Based Drug Delivery Systems
10.13303/j.cjbt.issn.1004-549x.2022.06.021
- VernacularTitle:基于红细胞的药物递送系统研究进展
- Author:
Kehui ZHU
1
;
Hong WANG
1
;
Rui ZHONG
1
;
Ye CAO
1
;
Jiaxin LIU
1
Author Information
1. Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, Chengdu 610052, China
- Publication Type:Journal Article
- Keywords:
red blood cell;
drug delivery carrier;
erythrocyte membrane;
red blood cell-derived vesicle
- From:
Chinese Journal of Blood Transfusion
2022;35(6):672-676
- CountryChina
- Language:Chinese
-
Abstract:
Red blood cells(RBCs), as the most abundant types of blood cells in the blood, have several advantages as a drug delivery system due to their ultra-long circulation half-life, good biocompatibility, and biodegradability. To date, a variety of RBCs-based drug delivery techniques have been developed for the treatment of infection diseases, cancers, chronic diseases, and autoimmune diseases. This review summarized the progress of RBCs related drug delivery systems, and discussed the advantages and disadvantages of different loading methods and their pre-clinical application progress, promoting the research and development of drug delivery.
