Changes of blood indicators in blood donors after COVID-19 vaccination
10.13303/j.cjbt.issn.1004-549x.2022.06.002
- VernacularTitle:无偿献血者接种新冠疫苗后相关血液指标变化情况研究
- Author:
Siyun XU
1
;
Songyan WU
1
;
Yunfeng PU
1
;
Suochun CAO
1
Author Information
1. Changzhou Blood Center, Changzhou 213000, China
- Publication Type:Journal Article
- Keywords:
COVID-19 vaccination;
blood donation;
routine blood test;
biomarker;
coagulation indexes
- From:
Chinese Journal of Blood Transfusion
2022;35(6):602-604
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To explore the changes of blood routine, biochemical indexes and coagulation indexes of voluntary blood donors after COVID-19 vaccination, so as to provide a scientific basis for blood donation strategy and to ensure blood safety. 【Methods】 From March to August 2021, 55 blood donors who had received COVID-19 vaccination were sampled at the 2nd, 4th and 8th weeks after vaccination for blood routine, biochemical and coagulation indexes testing. The changes were analyzed. 【Results】 At the second week after vaccination, abnormal blood routine indicators occurred 16(5.82%) occasions, abnormal biochemical indicators 159(36.14%) occasions; at the 4th week after vaccination, abnormal blood routine indicators 14(5.10%) occasions and abnormal biochemical indexes 151(34.32%) occasions. There was no difference in blood routine and biochemical indexes before and after vaccination(P>0.05). Among the coagulation indexes, the incidence of abnormal increase of FⅧ activity at the 2nd, 4th and 8th weeks after vaccination were 34.5%(19/55), 40%(22/55) and 50.9%(28/55), respectively. The the incidence of abnormal increase of TT were 3.6%(2/55), 7.2%(4/55) and 21.8%(12/55), respectively. Both TT and FⅧ activity had a tendency of increasing(P<0.05), APTT had an decreasing trend(P<0.05), and FIB content took on dynamical changes(P<0.05). 【Conclusion】 The blood indicators of blood donors after receiving COVID-19 vaccination are almost within the normal reference values. They can donate regularly according to the required interval, which may help to improve the potential transient changes of coagulation function.
