Experimental Branch Retinal Vein Occlusion in Albino Rats.
- Author:
Don Il HAM
1
;
Seong Jun KIM
;
Kwang CHANG
;
Hum CHUNG
Author Information
1. Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Retinal vein occlusion;
Animal model;
Rose bengal;
Laser Laser photocoagulation
- MeSH:
Animals;
Ganglion Cysts;
Light Coagulation;
Models, Animal;
Rats*;
Retinal Diseases;
Retinal Vein Occlusion*;
Retinal Vein*;
Retinaldehyde*;
Rose Bengal
- From:Journal of the Korean Ophthalmological Society
1997;38(7):1194-1202
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The retinal vein occlusion is one of the most common retinal diseases, and the establishment of animal model in rats will be a great help for further study. We occluded branch retinal veins with rose bengal dye injection followed by argon-green laser photocoagulation in albino rats. Retinal vein occlusion was maintained over 1 day in 35 eyes out of 47, maximally over 5 days. Retinal tissue damage was confined to the photocoagulated areas in most eyes and the loss of ganglion cells began when the occlusion persisted over 1 day. If the reproducibility is further increased, this will be a good animal model of retinal vein occlusion in albino rats.
