Retrospection and multivariate Logistic regression analysis of unqualified blood testing among voluntary blood donors in Guangzhou
10.13303/j.cjbt.issn.1004-549x.2022.08.019
- VernacularTitle:广州市无偿献血人群血液检测不合格情况回顾及多因素Logistics回归分析
- Author:
Junmou XIE
1
;
Haojian LIANG
1
;
Shiya LIN
1
;
Wenbo GAO
1
;
Rongsong DU
1
;
Yourong ZHENG
1
;
Hao WANG
1
Author Information
1. Guangzhou Blood Center, Guangzhou Key Laboratory of Medical Sciences (Blood Safety), Guangzhou 510095, China
- Publication Type:Journal Article
- Keywords:
voluntary blood donation;
blood screening;
unqualified rate;
Logistic regression
- From:
Chinese Journal of Blood Transfusion
2022;35(8):855-860
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To retrospectively analyze the unqualified blood screening results of voluntary blood donors in Guangzhou area during 2016~2020, and analyze various factors that affect the blood screening results, for the purpose of providing a scientific basis for recruitment and retention of blood donors, improving blood safety, and avoiding waste of blood resources. 【Methods】 A total of 1 548 204 voluntary blood donors in Guangzhou from 2016 to 2020 were selected as the research objects, and the blood samples were screened by dual ELISA and once NAT. The unqualified rate of different years and populations were counted and the analysis of risks of unqualified blood testing was performed by conditional Logistics regression. 【Results】 An overall unqualified rate of blood screening was 2.52% in Guangzhou from 2016 to 2020, the unqualified rate of every year showed a downward trend first and then an upward trend. HBsAg and ALT were the two primary deferral causes, the positive rate was 0.65%(10 129/1 548 204) and 1.22%(18 824/1 548 204), respectively; the unqualified rate in male blood donors3.10%(31 091/1 004 079) was significantly higher than that in female(P<0.05), and that in blood donors aged 18~25 was 1.84%(12 781/694 374), which was lower than the other three age groups (P<0.05). Fewer students(1.33%, 4 024/302 007) and bachelor degree donors(1.57%, 5 379/341 662) were deferred. Compared with individual blood donors, group blood donors’ deferral rate(2.62%, 21 307/813 664) was higher. The deferral rate of first-time blood donors(4.57%, 24 469/535 551) were higher than the repeated blood donors (P<0.05) , meanwhile, whole blood donors(2.84%, 38 111/1 340 678) higher than those apheresis donors (P<0.05). Gender, age, occupation, education, frequency and blood components donated were risk factors for unqualified blood screening. 【Conclusion】 The deferral rates of voluntary blood donors in Guangzhou showed an overall upward trend, from 2016 to 2022. HBsAg and ALT were the primary deferral causes, and there were differences in demographics and blood donation characteristics. To formulate targeted recruitment strategies according to the test results of voluntary blood donors, and strengthen the publicity of low-risk groups and the consultation and screening before blood donation, will be a great benefit for reducing the blood scrap and guaranteeing the blood safety.
