Cluster of Serogroup W-135 Meningococcal Disease in 3 Military Recruits.
10.3346/jkms.2015.30.5.662
- Author:
Yu Mi JO
1
;
Song Mee BAE
;
Yeon Ho KANG
Author Information
1. Division of Infectious Diseases, Konyang University College of Medicine, Daejeon, Korea. rhayjo@hanmail.net
- Publication Type:Case Reports
- Keywords:
Meningococcal Infections;
Neisseria meningitides, Serogroup W-135;
Military Personnel
- MeSH:
DNA, Bacterial/blood/cerebrospinal fluid;
Electrophoresis, Gel, Pulsed-Field;
Humans;
Male;
Meningitis/complications/*diagnosis/microbiology;
Military Personnel;
Multilocus Sequence Typing;
Neisseria meningitidis, Serogroup W-135/genetics/*isolation & purification;
Real-Time Polymerase Chain Reaction;
Sepsis/complications/*diagnosis/microbiology;
Young Adult
- From:Journal of Korean Medical Science
2015;30(5):662-665
- CountryRepublic of Korea
- Language:English
-
Abstract:
We describe a group of 3 cases of invasive meningococcal disease that occurred in a military training camp in April 2011. All three patients were hospitalized. Ultimately, two patients recovered and one died. One patient had meningitis, one patient had septicemia and meningitis, and the other had no definite septicemia or meningitis. Neisseria meningitidis serogroup W-135 was detected in the serum and cerebrospinal fluid (CSF) of all patients by real-time polymerase chain reaction. In the one case of mortality, two strains were isolated from the patient's blood and CSF. Using multilocus sequence typing analysis, these strains were identified as a novel sequence type, ST-8912. Special attention is required for the meningococcal disease in military camp because the military personnels are in high risk of contact transmission.
