Retrospective analysis of quality data of different blood components in Chongqing
10.13303/j.cjbt.issn.1004-549x.2022.09.024
- VernacularTitle:重庆地区不同血液制剂质量检测回顾性分析
- Author:
Zhanpeng LUO
1
;
Qi FU
1
;
Beinan ZENG
1
;
Chunyan YANG
1
;
Danrong YANG
1
;
Kai PENG
1
;
Juan WANG
1
Author Information
1. Chongqing Blood Center, Chongqing 400015, China
- Publication Type:Journal Article
- Keywords:
blood component;
quality test;
homogeneity
- From:
Chinese Journal of Blood Transfusion
2022;35(9):980-982
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To provide reference for formulating relatively unified quality control strategies and meeting the requirements of homogenization construction of blood banks across Chongqing area by retrospectively analyzing sampling results of different blood components during the past two years in all levels of blood banks in Chongqing area. 【Methods】 The key quality data of blood components prepared by 6 blood banks in Chongqing were analyzed retrospectively. According to the issuing units to the clinical during the past two years, the research objects were selected as leukocyte-depleted suspended RBCs, cryoprecipitate, pathogen inactivated fresh frozen plasma(FFP) and apheresis platelets. The quality data of the above-mentioned blood components from January 2019 to June 2021 were collected and analyzed. 【Results】 For leukocyte-depleted suspended RBCs(1U)prepared by 5 blood banks, statistically significant differences in Hb, residual white blood cells and hemolysis rate at the end of storage, except for Hct, were noticed(P<0.05). For cryoprecipitate, the content of blood coagulation factor Ⅷ and fibrinogen were statistically different among 3 blood banks in 1U specification(P<0.05) and among 5 blood banks in 2U specification(P<0.05). For pathogen inactivated FFP, the content of blood coagulation factor Ⅷ, plasma proteins, and residual methylene blue were statistically different among 3 blood banks(P<0.05). For apheresis platelets, Plt, white/red blood cells contamination and pH at the end of storage were statistically different among 3 blood banks(P<0.05). 【Conclusion】 The quality data of blood components, prepared by different blood banks, meet the requirements of national standard, however, certain differences are existing among blood banks.Key points during the process of collection, preparation, storage and transportation need to be cleared and unified, so as to reduce the differences between each other, and determine the direction and basis for homogeneity construction in the next step.
