Distribution of ABO, Rh, Mn, P, h blood groups and gene frequency in Lahu ethnic minority in Yunnan
- VernacularTitle:云南拉祜族人群ABO、Rh、MN、P、H血型分布及基因频率调查
- Author:
Haixia HU
1
;
Chengjiang FANG
1
;
Dan WU
1
;
Yu WU
1
;
Chen WANG
2
;
Zhongying WANG
2
;
Yuyu ZHANG
2
;
Dong XIANG
2
;
Zhenrong ZHANG
3
Author Information
- Publication Type:Journal Article
- Keywords: Yunnan; Lahu; ABO; Rh; MN; P1Pk; H blood groups; gene frequency
- From: Chinese Journal of Blood Transfusion 2022;35(10):1059-1061
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To understand the distribution and gene frequency of main red blood cell blood groups in Lahu ethnic minority and analyze the genetic characteristics of Lahu people. 【Methods】 1) ABO forward and reverse typing had been performed by microplate method; 2) Rh, MN, H, P1Pk and Mur antigen were tested by the tube method. If the ABO forward and reverse typing were incompatible, the tube method was used for confirmation. 【Results】 The distribution characteristics of blood group and gene frequency in Lahu ethnic minority were as follows: B>O>A>AB for ABO, with genotype frequency as p 11.1%, q 27.5% and r 61.4%; the frequency of Rh genotype was CDe 83.3%, cDE 12.0%, cDe 2.42%, CDE 2.32%, CdE 0%, Cde 0%, cdE 0% and cde 0%; M > MN>N for MN blood group, with genotype frequency as M 75.26% and N 24.74%; P1
