Profile of irregular antibodies among voluntary blood donors: 2018 to 2020 in Jiaxing
10.13303/j.cjbt.issn.1004-549x.2021.11.021
- VernacularTitle:2018年～2020年嘉兴地区无偿献血者不规则抗体分布特征
- Author:
Zhen LUO
1
;
Xiuwen NI
1
;
Jiayan TU
1
;
Jinhui WU
1
;
Jiayi SUN
1
;
Xiaoyuan LI
1
Author Information
1. Jiaxing Blood Center, Jiaxing 314000, China
- Publication Type:Journal Article
- Keywords:
blood donors;
irregular antibody;
distribution characteristics
- From:
Chinese Journal of Blood Transfusion
2021;34(11):1245-1247
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To study and analyze the profile of irregular antibodies among voluntary blood donors in Jiaxing area. 【Methods】 The ABO and RhD blood groups of all voluntary blood donors from November 2018 to November 2020 were detected by DIAGAST QWALYS 3 automatic blood group analyzer. According to routine serological screening program of irregular antibody, the samples reactive to O blood cell were sent to the reference laboratory for further identification of the antibody specificity, and the specificity and distribution characteristics of irregular antibodies were analyzed statistically. 【Results】 A total of 79 samples presenting irregular antibodies were yielded out of 90 854 blood samples, with a positive rate of 0.087%. More female samples (n=44) than male (n=35) (P<0.05). 29 donors aged 18 to 31, 33 aged 32 to 45, and 17 aged over 45 years old (P<0.05). 73 samples were RhD positive and 6 were RhD negative (P< 0.05). 40 only donated once, and 39 donated more than twice (P>0.05). 【Conclusion】 Female, RhD negative and more than 45 years old blood donors are more likely to present irregular antibodies, regardless of the number of blood donations.
