Blood transfusion efficacy in patients with major and minor cross-match incompatibility: analysis of 17 cases
10.13303/j.cjbt.issn.1004-549x.2021.11.013
- VernacularTitle:主次侧交叉配血不合患者输血疗效分析
- Author:
Yuqing WANG
1
;
Hang LEI
1
;
Songsong GONG
1
;
Xuefeng WANG
1
;
Xiaohong CAI
1
Author Information
1. Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
- Publication Type:Journal Article
- Keywords:
blood transfusion;
cross-match incompatibility;
ABO blood type
- From:
Chinese Journal of Blood Transfusion
2021;34(11):1218-1221
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To compare the transfusion effects of ABO homotype leukocyte depleted suspended RBC and washed RBC in patients, who present major and minor cross-match incompatibility, DAT+, IAT+ and autoantibody+ . 【Methods】 The hemoglobin and total bilirubin of patients before and after transfusion were detected, and statistical analysis was conducted by IBM SPSS Statistics 22.0 software. 【Results】 34 transfusions were performed in 17 patients with major and minor cross-match incompatibility. Both leukocyte depleted suspended RBC and washed RBC significantly increased Hb level(P<0.001)but not TBIL level(P>0.05), with similar transfusion efficacy(P>0.05). After t, Hb levels(g/L) increased by 11.35±8.07 and 13.94±9.017, and TBIL(μmol/L) decreased by 25.76±88.63 and 6.91±9.39, respectively, after the transfusion of leukocyte depleted suspended RBC and washed RBC per unit. 【Conclusion】 For blood recipients with major and minor cross-match incompatibility, both ABO homotype leukocyte depleted suspended RBC and washed RBC, given in time, were effective. However, washed RBC is secondary choice due to long preparation time and short storage time.
