Effectiveness of platelet transfusion in children receiving extracorporeal membrane oxygenation
10.13303/j.cjbt.issn.1004-549x.2021.11.011
- VernacularTitle:使用体外膜肺氧合技术治疗的患儿血小板输注效果分析
- Author:
Chengyun WANG
1
;
Yuwei GU
1
;
Ping GU
1
;
Qiuhui PAN
1
;
Jing WANG
1
Author Information
1. Department of Transfusion, Shanghai Children′s Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China
- Publication Type:Journal Article
- Keywords:
extracorporeal membrane oxygenation;
platelet transfusion;
threshold;
effectiveness analysis
- From:
Chinese Journal of Blood Transfusion
2021;34(11):1213-1215
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To explore the clinical effectiveness of platelet transfusion during pediatric extracorporeal membrane oxygenation (ECMO). 【Methods】 Neonates and children treated with ECMO and received platelets transfusion at least once in the Department of Cardiothoracic Surgery, Shanghai Children′s Medical Center in 2020 were enrolled in our research. Platelet count was measured 24 hours before and after each platelet transfusion, and the corrected count increment (CCI) was calculated for effectiveness estimation of platelet transfusion. The research objects were divided into three groups based on the platelet count before transfusion, and the effective rates of each group were calculated. 【Results】 Thirty-seven patients received 79 platelet transfusions (2.14±1.21 on average), among which 39 were effective (49.37%) and 40 were refractory (50.63%). The effective rates of group 1, group 2 and group 3 were 1, 67.74%, 40.91%, and 34.62%, respectively. 【Conclusion】 The restricted platelet transfusion strategy, on the premise of ensuring life safety, is preferred for children treated with ECMO.
