Characteristics and correlation analysis of thromboelastogram and coagulation related indexes in patients with preeclampsia
10.13303/j.cjbt.issn.1004-549x.2021.11.009
- VernacularTitle:子痫前期患者血栓弹力图和凝血相关指标变化特点及相关性分析
- Author:
Yizhi GAO
1
;
Hengshi XU
2
;
Fengling CHEN
2
;
Peiqi LU
1
;
Zidan SHEN
1
Author Information
1. Shanghai MCC Hospital, Shanghai 200941, China
2. Shanghai Ninth People′s Hospital, Shanghai Jiao Tong University School of Medicine
- Publication Type:Journal Article
- Keywords:
preeclampsia;
thromboelastogram(TEG);
coagulation correlation index
- From:
Chinese Journal of Blood Transfusion
2021;34(11):1207-1209
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To observe the characteristics and correlation analysis of thromboelastogram (TEG) and platelet related indexes in patients with preeclampsia in late pregnancy. 【Methods】 88 patients with preeclampsia in late pregnancy treated in the Obstetrics Department of Shanghai Ninth People′s Hospital (Northern Hospital) from June 2017 to June 2020 were selected as observation group, and 288 normal pregnant women in late pregnancy with normal prenatal examination were selected as the control. The median elbow vein blood of the two groups were sampled. The TEG and coagulation related indexes of the two groups were compared, and the relationship between TEG and coagulation related indexes in patients with preeclampsia were analyzed. 【Results】 The K, MA, TT, INR and PLT value in the observation group, relative to controls, were significantly higher (P<0.01), but Angle, PT, and APTT value were significantly lower (P<0.01). The variance K and MA were negatively correlated with PT and APTT (P<0.05), but positively correlated with TT, INR and Plt (P<0.05). Angle was positively correlated with PT and APTT (P<0.05), but negatively correlated with TT, INR and Plt(P<0.05). 【Conclusion】 Routine TEG detection can effectively evaluate the coagulation state of patients with preeclampsia, who are often accompanied by coagulation dysfunction, help to guide clinical early prevention and intervention, and reduce the risk of perinatal hemorrhage and embolism diseases, which is worthy of popularizing in clinical.
