Qualitative analysis of volatile organic components in chemicals using headspace gas chromatography-mass spectrometry
10.20001/j.issn.2095-2619.20230616
- VernacularTitle:顶空气相色谱-质谱联用法检测化学品中挥发性有机组分
- Author:
Ruibo MENG
1
;
Weifeng RONG
;
Jiawen HU
;
Jiaheng HE
;
Jing YUAN
;
Jingjing QIU
;
Zuokan LIN
;
Ziqun ZHANG
;
Banghua WU
Author Information
1. Guangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, Guangdong 510300, China
- Publication Type:Journal Article
- Keywords:
Chemicals;
Volatile organic components;
Gas chromatography-mass spectrometry;
Headspace analysis method;
Qualitative analysis
- From:
China Occupational Medicine
2023;50(3):325-329
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a rapid qualitative analysis method for volatile organic components in chemicals. Methods Headspace gas chromatography-mass spectrometry was used to qualitatively determine 19 volatile organic components, including benzene, 1,2-dichloroethane, and n-hexane, in chemicals. Different sample amounts, heating temperatures, heating times, and sample volumes were analyzed to assess their effects on detection results and optimize sampling conditions. Results Based on the set chromatography, the optimal sampling process of this method was as follows： 5.0 g sample in a 20.0 mL headspace bottle, incubated at 40 ℃ for 30 minutes in a constant-temperature drying incubator, and a 1.00 mL headspace gas injection. The within-run and between-run relative standard deviations of all components ranged from 0.00% to 21.05% and 0.00% to 33.33%, respectively. The samples stored in sealed glass containers were stable at room temperature for at least 60 days. Conclusion This method offers simplicity, good reproducibility, and stability, making it suitable for rapid qualitative analysis of volatile organic components in chemicals.
