Recent Insights into Mechanisms Governing Breast Cancer Dormancy
10.3971/j.issn.1000-8578.2023.23.0602
- VernacularTitle:乳腺癌休眠机制研究进展
- Author:
Lanjing MA
1
;
Baihong ZHANG
Author Information
1. Department of Oncology, 940th Hospital of Joint Logistics Support Force of People's Liberation Army, Lanzhou 730050, China
- Publication Type:Research Article
- Keywords:
Breast cancer;
Tumor dormancy;
Autophagy;
Immune escape;
Epigenetic;
Metabolism reprogramming;
Tumor microenvironment;
Non-coding RNA
- From:
Cancer Research on Prevention and Treatment
2023;50(12):1237-1242
- CountryChina
- Language:Chinese
-
Abstract:
Tumor dormancy refers to the status of disseminated cancer cells that remain in a viable yet not proliferating state for a prolonged period. Dormant cells will eventually "re-awake" resume their proliferation, and produce overt metastasis. The dormancy mechanism of cancer has attracted attention because of the close relationship between late recurrence and tumor dormancy. In this review, we illustrate the latest discoveries on the biological underpinnings of breast cancer dormancy and offer clinicians an overview of dormancy in breast cancer to guide them in the basic understanding of the complexity that underlies this process.
