Anti-aging Effect of Ginseng Radix et Rhizoma：A Review
10.13422/j.cnki.syfjx.20230647
- VernacularTitle:人参抗衰老研究进展
- Author:
Hongrong LI
1
;
Shixiong ZHANG
1
;
Yawen LI
1
;
Xuan LU
1
;
Runtao ZHANG
1
;
Xiaogang SHEN
1
Author Information
1. Hebei Institute of Integrated Traditional Chinese and Western Medicine，Shijiazhuang 050035，China
- Publication Type:Review
- Keywords:
population aging;
Ginseng Radix et Rhizoma;
anti-aging;
saponins;
polysaccharides;
oxidative stress;
mitochondrial homeostasis
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2024;30(3):196-207
- CountryChina
- Language:Chinese
-
Abstract:
Ginseng Radix et Rhizoma（GRR） has the function of replenishing vital energy and can lighten the body and prolong the life when taken for a long time， which is suitable for the development of anti-aging products， so this paper intends to sort out the progress of anti-aging research on GRR. After combing， the results of modern studies have shown that a variety of components in GRR have anti-aging effect， which can prolong the lifespan of aging animal models， as well as delay the aging of various systems. The anti-aging mechanisms mainly include anti-cellular senescence， anti-oxidative stress， inhibiting telomere shortening， maintaining mitochondrial homeostasis and so on. The anti-aging ingredients of GRR involved in the researches mainly include ginsenoside Rg1 and ginsenoside Rb1， in addition， ginsenoside Rg3， ginsenoside Rd， ginsenoside Rg2， ginsenoside Re， ginsenoside Rb2， oligosaccharides of GRR， polysaccharides of GRR， water extract of GRR， total saponins of Panax ginseng stems and leaves are also included. Therefore， under current background of population aging， the in-depth development of GRR and its transformation into anti-aging products are of great significance for delaying senility and improving the health conditions of aging population.
