Langerhans cell histiocytosis presenting as anterior neck mass in a child: A case report

Author: Kristine Mae Betansos ¹ ; Melissa Joyanne Cachero ¹ ; Caridad Santos ¹ ; Eve Fernandez ¹ ; Marichu Mabulac ¹ ; Lorna Abad ^{1
,

2}
Author Information

1. Section of Pediatric Endocrinology, Philippine Childrens Medical Center, Quezon City, Philippines
2. Department of Pediatrics, Philippine General Hospital, Manila
Publication Type:Case Reports
Keywords: Multisystem LCH
MeSH: Histiocytosis, Langerhans-Cell; Thyroid Gland
From: Journal of the ASEAN Federation of Endocrine Societies 2023;38(2):149-153
CountryPhilippines
Language:English
Abstract: Thyroid involvement in Langerhans Cell Histiocytosis (LCH) is rare. We report a 10-year-old Filipino male who presented with a rapidly enlarging goiter. Computed tomography scan showed thyroid and bilateral submandibular masses with malignant features, pulmonary blebs and hepatic cysts. Ultrasound-guided core needle biopsy findings were consistent with LCH and chemotherapy was initiated. This case demonstrates that LCH should be considered in patients with goiter. Multidisciplinary management is warranted to achieve proper diagnosis and institute timely treatment.
Full text:2621-Article Text-25135-1-10-20231115.pdf