Cross - species regulation and underlying mechanisms of parasite - derived non-coding RNAs: a review.
10.16250/j.32.1374.2023055
- Author:
Y DAI
1
,
2
;
Q YANG
1
,
2
Author Information
1. Guangxi University of Chinese Medicine
2. Guangxi Key Laboratory of Translational Medicine for Treating High-Incidence Infectious Diseases with Integrative Medicine, Nanning, Guangxi 530200, China.
- Publication Type:Journal Article
- Keywords:
Competing endogenous RNA;
Cross-species regulation;
Extracellular vesicle;
Non-coding RNA;
Parasite
- MeSH:
Animals;
Parasites;
Gene Regulatory Networks;
MicroRNAs/metabolism*;
RNA, Messenger/genetics*;
RNA, Circular/genetics*;
RNA, Competitive Endogenous
- From:
Chinese Journal of Schistosomiasis Control
2023;35(5):529-533
- CountryChina
- Language:Chinese
-
Abstract:
Parasite-derived non-coding RNAs (ncRNAs) not only contribute to life activities of parasites, and microRNA (miRNA), long non-coding RNA (lncRNA), and circular RNA (circRNA) may generate a competitive endogenous RNA (ceRNA) regulatory network with host miRNAs and mRNAs via extracellular vesicles, thereby participating in infection and pathogenic processes. This article presents an overview of characterizing ncRNAs derived from parasites and the cross-species regulatory role of parasite-derived ncRNAs in host gene expression and its underlying mechanisms.
