Research progress in biomimetic nano formulations of biofilms
10.11665/j.issn.1000-5048.2023020603
- VernacularTitle:生物膜仿生纳米制剂研究进展
- Author:
Qiang ZHANG
1
;
Xi LUO
;
Yongrui BAO
;
Shuai WANG
;
Tianjiao LI
;
Xiansheng MENG
Author Information
1. 辽宁中医药大学药学院
- Publication Type:Journal Article
- Keywords:
biomimetic nano-drugs;
bionic drug delivery system;
biomembrane;
targeted therapy
- From:
Journal of China Pharmaceutical University
2023;54(5):544-552
- CountryChina
- Language:Chinese
-
Abstract:
Biomimetic nano formulations of biofilms have low immunogenicity, high targeting, and good biocompatibility, and can avoid being cleared by the endothelial reticular system, thus with in longer blood circulation time in the body.This article mainly reviews the main types as well as advantages and disadvantages of biomimetic nano formulations of biofilms, including tumor cell membranes, red blood cell membranes, platelet membranes, white blood cell membranes, stem cell membranes, extracellular vesicles (exosomes, microvesicles, and apoptotic bodies), endoplasmic reticulum membranes, and composite biofilms, with also a prospect of the challenges facing biomimetic nano formulations of biofilms and their future development based on their current research status, aiming to provide some insight for further research on biomimetic nano formulations of biofilms.
