Research progress of mechanism and risk factors of retinal vein occlusion
10.3980/j.issn.1672-5123.2024.1.14
- VernacularTitle:视网膜静脉阻塞机制及危险因素研究进展
- Author:
Shui LI
1
;
Huajing YANG
1
;
Jiale DAI
1
;
Jianbin CHEN
1
Author Information
1. Department of Ophthalmology, Tongji Hospital, Tongji Medical Collage, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China
- Publication Type:Journal Article
- Keywords:
retinal vein occlusion;
macular edema;
mechanism;
risk factors;
review
- From:
International Eye Science
2024;24(1):72-76
- CountryChina
- Language:Chinese
-
Abstract:
Retinal vein occlusion(RVO), the second most prevalent retinal vascular disease, has complex pathophysiological mechanism. Except for mechanical pressure on blood vessel, inflammation and endothelin have been confirmed to be involved in the pathogenesis of RVO. However, its specific mechanism remains unclear. Hypertension, diabetes and dyslipidemia have been previously shown to be the most common risk factors in elder population, while recent studies found that coagulation and hemorheological abnormalities are more common in people under 50 years old. Ocular risk factors including glaucoma, high corrected intraocular pressure and retinal vessels abnormality, have gained more and more attention. These factors probably exert a synergistic effect when present simultaneously in the same patient. Therefore, early identification and intervention of those factors could lower the incidence of RVO. This article aims to review recent research and summarize existing mechanism and theories, giving some new research ideas for potential therapy targets and providing references for identification and management of risk factors.
