EFFECTS OF ELLIPIN TO PROLIFERATION ASSAY OF HEPATIC CANCER CELLS
- VernacularTitle: ХОРТ ХАВДРЫН ЗАРИМ ТӨРЛИЙН ЭСИЙН ҮРЖИЛД
- Author:
Л.Хүрэлбаатар
;
О.Одгэрэл
;
Ц.Оюунсүрэн
;
П.Эрдэнэбаатар
- Publication Type:Journal Article
- Keywords:
Ellipin;
HepG2;
cell lines;
cell proliferation
- From:
Mongolian Pharmacy and Pharmacology
2012;1(1):24-26
- CountryMongolia
- Language:Mongolian
-
Abstract:
Introduction׃The Ellipin, prepared from bovine liver is a newly developed anticancer agent containing several important fatty acids. Goal: To investigate effects of Ellipin to proliferation assay of hepatic cancer cell function. Materials and Methods: This study was conducted in the Laboratory of Molecular Biology, Institute of Biology, MAS, The Ellipin was developed in the Drug Research Institute of Monos group. HepG2,HCC,23132/87,MDCK,cells lines and the primary liver cancer cells(PCC)we re used for proliferation assay. Results: The results of proliferation assay showed that the ellipin decreased the proliferation activity of HepG2 and PCC cells depending on concentrations: in 50µg/ml 2-3 times, 250 µg/ml fully stopped cells divisions. Conclusions: Our results showed that the Ellipin suppresses HepG2 cancer cell proliferation Key words: Ellipin, HepG2, cell lines, cell proliferation. Figures 4, References 4
