OF BIOLOGICAL ACTIVITY COMPOUNDS IN SOME
- VernacularTitle: None
- Author:
Sugarjav E
1
;
Chimedragchaa Ch
Author Information
1. Institute of Traditional Medicine and Technology
- Publication Type:Journal Article
- Keywords:
Leonurus Sibiricus L.;
Ephedra
- From:
Mongolian Pharmacy and Pharmacology
2015;7(2):104-106
- CountryMongolia
- Language:English
-
Abstract:
The aim of this study is to investigate biological activity compounds in Mongolian traditional medicinal plants, such as Leonurus Sibiricus L., Ephedra Przewalskii Stapt. and Lonicera Altaica Pall. In the phytochemical research, biological active substance was determined by using paper chromatography and thin-layer chromatography, on silica gel plats. We determined the total content of phenolic compound by the Folin–Ciocalteu method, total alkaloid, and tannin by titrimetric method and total fl avonoid by spectrophotometric method. The following biological active substances were detected: catechin, ephedrine, anthocyan and rutin. As a result of our research, it was determined that the total alkaloids was 0.02 percent, tannin was 9.03 percent in herba Ephedra Przewalskii Stapt , total phenolic compound was 3.3 percent in Leonurus Sibiricus L. and total fl avonoid was 6.6 percent in fruits Lonicera Altaica Pall. Key words: Leonurus Sibiricus L., Ephedra Przewalskii Stapt., Lonicera Altaica Pall., thinlayer chromatography, phytochemical INTRODUCTION Ephedra przewalskii is a species of Ephedra that is native to Central Asia, Mongolia,Pakistan, and parts of China ( Gansu, Inner Mongolia, Ningxia, Qinghai, and Tibet) [1][2]. Ephedra przewalskii is widely distributed in desert regions of Mongolia such as khobdo, Dornogovi, and Mongol Altai [3]. Ephedrae herba has been used in traditional Chinese, Mongolia and Japanese (Kampo) medicine from ancient times. In Mongolia, Ephedra przewalskii herba has traditionally been used by indigenous people for a variety of medicinal purposes, including treatment of asthma, hay fever, and the common cold [4]. Herba of Ephedra przewalskii are considered to be rich source of a large amount of bioactive substances like alkaloids, catechin, fatty oil and carbohydrate [3]. Leonurus Sibiricus L., is a member of the family Lamiaceae, is widely distributed in forested area and desert regions of Mongolia such as Khangai, Khuvsgul, Khentii Mongol Daguur, and Mongol Altai [5]. In traditional Mongolian medicine aerial parts of Leonurus Sibiricus L., used for treatment of diseases of heat reduction, removal of poisonous diseases, soothing and reducing hypertension. Aerial parts of Leonurus Sibiricus L.are considered to be rich source of a large amount of bioactive substances like fl avonoids, alkaloids, tannin and organic acids [5]. In mongolia has described four species of Lonicera Altaica Pall (Caprifoliaceae). Their habitats are khuvsgul, khangai, Khentii, khobdo, Mongolian altai, and depression of great lakes, mongol daguur and the Gobi-altai (three Beauty of gobi) region of the country. Lonicera altaica in Mongolian traditional medicine is reputed for its treatment of liver, stomach and cardiac disorders, Moreover, it is known for its rejuvenation action [6]. Fruit of Lonicera Altaica Pall. is considered a rich source of bioactive substances like fl avonoids, anthocyanins, vitamin C and amino acids [6].