Role of T lymphocytes in primary sclerosing cholangitis
10.3969/j.issn.1001-5256.2023.12.026
- VernacularTitle:T淋巴细胞在原发性硬化性胆管炎中的作用
- Author:
Ziyi LI
1
;
Wanjie ZHANG
1
;
Fuchun WANG
1
;
Xiaorong MAO
1
;
Junfeng LI
1
Author Information
1. The First Clinical Medical College of Lanzhou University， Lanzhou 730000， China
- Publication Type:Review
- Keywords:
T lymphocytes;
Primary Sclerosing Cholangitis;
Pathogenesis
- From:
Journal of Clinical Hepatology
2023;39(12):2926-2931
- CountryChina
- Language:Chinese
-
Abstract:
Primary sclerosing cholangitis （PSC） is an immune-mediated chronic cholestatic liver disease and can progress to end-stage liver diseases such as liver cirrhosis and liver failure， and there are still no effective treatment methods at present. Studies have found that T lymphocytes are closely associated with the development and progression of PSC. This article reviews the role of T lymphocytes in PSC， so as to provide new ideas for research on the pathogenesis of PSC and the clinical diagnosis and treatment of PSC.
