Research advances in lean nonalcoholic fatty liver disease
10.3969/j.issn.1001-5256.2023.12.024
- VernacularTitle:瘦型非酒精性脂肪性肝病的研究进展
- Author:
Yujuan ZHANG
1
;
Xiqiao ZHOU
2
Author Information
1. The First Clinical Medical College of Nanjing University of Chinese Medicine， Nanjing 210000， China
2. Department of Endocrinology， The Affiliated Hospital of Nanjing University of Chinese Medicine， Nanjing 210000， China
- Publication Type:Review
- Keywords:
Nonalcoholic Fatty Liver Disease;
Somatotypes;
Diagnosis;
Therapeutics;
Risk Factors
- From:
Journal of Clinical Hepatology
2023;39(12):2914-2919
- CountryChina
- Language:Chinese
-
Abstract:
Nonalcoholic fatty liver disease （NAFLD） is currently the main cause of chronic liver disease worldwide， and it can progress to hepatitis， liver fibrosis， liver cirrhosis， and even hepatocellular carcinoma. Although obesity plays a key role in the development of NAFLD， more and more studies have confirmed that NAFLD still exists in lean individuals， and lean NAFLD is associated with an increased risk of death and accelerated disease progression. Therefore， lean NAFLD also deserves careful evaluation and follow-up； however， we still know little about the pathophysiological mechanism of lean NAFLD. This article reviews the etiology， diagnosis， treatment， and prognosis of lean NAFLD.
