Successful long-term management of late-stage precursor-targeted immune-mediated anemia with prednisolone and mycophenolate mofetil in a dog
- Author:
Doyun KIM
1
;
Woo-Jin SONG
;
Sung-Soo KIM
;
Soyoung JEONG
;
Hyun Jeong HONG
;
Youngmin YUN
Author Information
- Publication Type:Case Report
- From:Korean Journal of Veterinary Research 2023;63(2):e8-
- CountryRepublic of Korea
- Language:English
- Abstract: A 13-year-old neutered male Maltese dog presented to our hospital with lethargy and anorexia. Laboratory abnormalities included severe non-regenerative anemia (hematocrit, 12.9%; reticulocyte count 12.8 K/μL). The cytology of bone marrow revealed erythroid hypercellularity with mild myelofibrosis. Therefore, late-stage precursor-targeted immune-mediated anemia (PIMA) was diagnosed. Multimodal treatment including 2 immunosuppressant drugs (prednisolone and mycophenolate mofetil), antithrombic drug (clopidogrel), and blood transfusion was performed. The dog showed complete remission from PIMA, and the total duration of follow-up was 622 days. This is the first case report of canine PIMA managed successfully with prednisolone and mycophenolate mofetil in Korea.
