Clinical and Radiological Analysis of Reversible Posterior Leukoencephalopathy Syndrome in Children.
10.3345/kjp.2007.50.9.901
- Author:
Hae Ri LIM
1
;
Hye Eun SEO
;
Sun Hak KWON
Author Information
1. Department of Pediatrics, college of Medicine, Kyungpook National University, Daegu, Korea. shkwon@knu.ac.kr
- Publication Type:Original Article
- Keywords:
Leukoencephalopathy;
Seizure;
Cyclosporin;
Steroid
- MeSH:
Blood Pressure;
Brain;
Child*;
Cyclosporine;
Humans;
Leukoencephalopathies;
Magnetic Resonance Imaging;
Male;
Medical Records;
Posterior Leukoencephalopathy Syndrome*;
Retrospective Studies;
Seizures
- From:Korean Journal of Pediatrics
2007;50(9):901-904
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
clinical and radiologic findings that mainly involve the white/gray matter of the parieto-occipital lobes. The purpose of this study was to determine its clinical and radiological characteristics. METHODS: A total of 15 pateints were involved in the study. Their medical records and radiological features of brain MRI were retrospectively reviewed and analyzed. RESULTS: Fifteen pateints were involved. (9 males and 5 females). The patients' ages ranged from 2-20 years (mean age:10 years). The brain MRI revealed fairly symmetric areas of increased T2 signal involving both white and gray matter of parieto-occipital regions. The condition seemed to be associated with cyclosporin A and steroid therapy or a variety of other conditions in which blood pressure rises acutely. CONCLUSION: Reversible posterior leukoencephalopathy syndrome is a complicated neurological condition, but a better understanding of this complex syndrome may obviate unnecessary investigations and lead to prompt and appropriate management of the associated problems.
