Acyclovir-induced Acute Renal Failure in a Patient With Suspected Acute Retinal Necrosis Syndrome.
10.3341/jkos.2010.51.11.1528
- Author:
Joon Hee CHO
1
;
Joo Hyun JANG
;
Dong Hun LEE
;
Young Ki LEE
;
Jung Woo NOH
;
Ji Hyun BAE
;
Ha Kyoung KIM
Author Information
1. Department of Ophthalmology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. ophkim@hallym.or.kr
- Publication Type:Case Report
- Keywords:
Acute renal failure;
Acute retinal necrosis syndrome;
Acyclovir
- MeSH:
Acute Kidney Injury;
Acyclovir;
Eye;
Humans;
Male;
Middle Aged;
Retinal Necrosis Syndrome, Acute
- From:Journal of the Korean Ophthalmological Society
2010;51(11):1528-1531
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report a case of acyclovir-induced acute renal failure (ARF) suspected as acute retinal necrosis syndrome. CASE SUMMARY: The authors report a 55-year-old male patient who presented with left eye visual disturbance due to suspected acute retinal necrosis syndrome. Non-oliguric ARF developed after the infusion of intravenous acyclovir (850 mg every 8 hours). The patient did not show any uremic symptoms or signs. The crystal was not discovered in the urine. After stopping the acyclovir infusion and hydration, acyclovir-induced ARF was reversed. CONCLUSIONS: Although possessing critical nephrotoxicity, acyclovir is a useful antiviral drug. Therefore, when using acyclovir, the importance of hydration and preventing acyclovir-induced ARF should be considered.
