Intrathecal injection of magnesium sulfate: shivering prevention during cesarean section: a randomized, double-blinded, controlled study.
10.4097/kjae.2013.65.4.293
- Author:
Seyed Hamid Reza FAIZ
1
;
Poupak RAHIMZADEH
;
Farnad IMANI
;
Ali BAKHTIARI
Author Information
1. Department of Anesthesiology and Pain Medicine, Rasoul-Akram Medical Center, Tehran University of Medical Sciences, Tehran, Iran. p-rahimzadeh@tums.ac.ir
- Publication Type:Randomized Controlled Trial ; Original Article
- Keywords:
Bupivacaine;
Cesarean section;
Magnesium sulfate;
Shivering
- MeSH:
Anesthesia, Conduction;
Anesthesia, Spinal;
Body Temperature Regulation;
Bupivacaine;
Cesarean Section*;
Female;
Humans;
Hypothermia;
Injections, Spinal*;
Magnesium Sulfate*;
Pregnancy;
Shivering*
- From:Korean Journal of Anesthesiology
2013;65(4):293-298
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Regional anesthesia is known to significantly impair thermoregulation and predispose patients to hypothermia. We hypothesized that the addition of an intrathecal injection of magnesium sulfate (MgSO4) to bupivacaine would improve perioperative shivering in female patients undergoing elective caesarean section. METHODS: In a block-randomized, double-blinded, controlled trial 72 patients scheduled for elective caesarean section with spinal anesthesia were separated into two groups. In the treatment group, 2 ml of 0.5% bupivacaine plus 25 mg MgSO4 (0.5 ml) were injected intrathecally, and in the control group 2 ml of 0.5% bupivacaine plus 0.5 ml normal saline were injected intrathecally. Core temperature was measured before and after drug injection at predetermined intervals. Sedation was graded using the Ramsay sedation scale. RESULTS: No significant intergroup differences in appearance of shivering were seen immediately or at 5, 30, 40, 50, 60, and 90 min after block administration. However, at 10, 15, and 20 min post block, there was a significant difference in shivering. The group administered MgSO4 showed lower shivering grades compared with the control group. Core temperature was significantly reduced in the MgSO4 group compared to the normal saline group 30 min after blocking. CONCLUSIONS: Intrathecal injection of MgSO4 improved perioperative shivering in female patients undergoing elective caesarean section.
