Synthesis of carbutamine, an antidiabetic drug
- Author:
Chau Dinh Phan
- Publication Type:Journal Article
- Keywords:
carbutamine
- MeSH:
Pharmaceutical Preparations;
Hypoglycemic Agents
- From:Pharmaceutical Journal
1998;262(2):13-14
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Purpose: find out synthesis of carbutamine. Experiment: from acetanilid through 5 steps: (1) Preparing acetamidobenzen sulfoclorua; (2) Preparing p-acetamindobenzensulfonamid; (3) Preparing p-acetamidobenzen sulfonylure; (4) Preparing N1-nbutyl, N2-su;lanilylure. (5) Product completely resemble carbutamid, which extracted refinement from bucarban tablet of Hungary, as infra-red spectrum and sensitivity.
