Associations of Polyp Characteristics in Children and Adolescents Presenting with Less Than Five Colorectal Polyps: A Full Colonoscopy Is Still Required
- Author:
Ju Young KIM
1
;
Yu Bin KIM
;
Sujin CHOI
;
Yoo Min LEE
;
Hyun Jin KIM
;
Soon Chul KIM
;
Hyo-Jeong JANG
;
So Yoon CHOI
;
Dae Yong YI
;
Yoon LEE
;
You Jin CHOI
;
Yunkoo KANG
;
Kyung Jae LEE
;
Suk Jin HONG
;
Jun Hyun HWANG
;
Sanggyu KWAK
;
Byung-Ho CHOE
;
Ben KANG
Author Information
- Publication Type:Original Article
- From:Gut and Liver 2023;17(3):441-448
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background/Aims:A full colonoscopy is currently required in children and adolescents with colorectal polyps, because of their potential of neoplastic transformation and complications such as intussusception. We aimed to analyze the associations of polyp characteristics in children and adolescents with colorectal polyps. Based on these findings, we also aimed to reevaluate the necessity of conducting a full colonoscopy.
Methods:Pediatric patients <18 years of age who had undergone a colonoscopic polypectomy and those with <5 colorectal polyps were included in this multicenter, retrospective study. Baseline clinicodemographics, colonoscopic and histologic findings were investigated.
Results:A total of 91 patients were included. Multivariate logistic regression analysis showed that polyp size was the only factor associated with the presence of any polyps located proximal to the splenic flexure (odds ratio [OR], 2.25; 95% confidence interval [CI], 1.28 to 4.28; p=0.007). Furthermore, polyp location proximal to the splenic flexure and sessile morphology were associated with the presence of any adenomatous polyp (OR, 8.51; 95% CI, 1.43 to 68.65; p=0.023; OR, 18.41; 95% CI, 3.45 to 173.81; p=0.002, respectively).
Conclusions:In children and adolescents presenting with <5 colorectal polyps, polyp size and the presence of any adenomatous polyp were positively associated with polyp location proximal to the splenic flexure. This finding supports the necessity of a full colonoscopic exam in pediatric patients with colorectal polyps for the detection of polyps before the occurrence of complications such as intussusception or neoplastic transformation.
