Trends in Antibiotic Use in a Single University Hospital.
10.14192/kjnic.2013.18.2.44
- Author:
Kang Il JUN
;
Hei Lim KOO
;
Min Kyung KIM
;
Chang Kyung KANG
;
Min Jae KIM
;
Shin Hye CHUN
;
Jung Sook SONG
;
Hyang Sook KIM
;
Nam Joong KIM
;
Eui Chong KIM
;
Myoung Don OH
- Publication Type:Original Article
- Keywords:
Anti-bacterial agents;
University hospitals;
Utilization
- MeSH:
Adult;
Aminoglycosides;
Anti-Bacterial Agents;
Cephalosporins;
Classification;
Colistin;
Hospitals, University;
Humans;
Korea;
World Health Organization;
Linezolid
- From:Korean Journal of Nosocomial Infection Control
2013;18(2):44-50
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The aim of this study was to evaluate antibiotic consumption by adult patients at a single university hospital in Korea between 2001 and 2012. METHODS: We used the 2004 World Health Organization Anatomical Therapeutic Chemical Classification System definition of defined daily doses (DDD) per 1,000 patient-days to calculate the annual antibiotic consumption for 18 antibiotic groups. Chi-square linear-by-linear analysis was performed to evaluate antibiotic consumption trends for each group. RESULTS: Average annual antibiotic consumption during 2001-2012 was 644.6 DDD/1,000 patient-days (standard deviation, 33.3 DDD/1,000 patient-days). Although no statistically significant change was observed during the study period, consumption of first- and second-generation cephalosporins, and aminoglycosides was significantly decreased, while that of beta-lactam/beta-lactamase inhibitors, fourth-generation cephalosporins, carbapenem, glycopeptide, linezolid, colistin, and quinolone increased significantly. CONCLUSION: The total amount of prescribed antibiotics did not change, but the use of broad-spectrum antibiotics increased during the study period.
