1.Molecular and Cellular Mechanisms of Spermatogenesis.
Journal of Korean Society of Endocrinology 2001;16(6):562-571
No abstract available.
Spermatogenesis*
2.Effect of Homologous Human Semen Mixtures on Viability of Sperm.
Korean Journal of Urology 1974;15(4):251-258
The causes of male infertility have been well delineated in numerous textbooks and articles. These are divided into six major categories such as failure of spermatogenesis, failure of sperm maturation, failure of sperm transportation, failure of semen composition, failure of hormonal system and failure of ejaculation. Besides these, the motile activity of sperm has been regarded as an important factor for the impregnation This clinical study has been undertaken to examine the effects of hemologous human semen mixtures upon the motile time of the spermatozoa, and the result are presented as follows; Group 1, Mixture of Normospermia and Normospermia: 10 mixtures Normospermia-A: 471. 9 minutes of aver age sperm motile time Normospermia-B: 369. 4 minutes of average sperm motile time Normo-A+Normo-B mixture: 452. 5 minutes of average sperm motile time Group 2, Mixture of Normospermia and Oligospermia: 10 mixtures Normospermia: 445.3 minutes of average sperm motile time Oligospermia: 376.2 minutes of average sperm motile time Normo+Oligo mixture: 456. 1 minutes of average sperm motile time Group 3, Mixture of Normospermia and Azoospermia; 8 mixtures Normospermia: 433. 3 minutes of average sperm motile time Azoospermia: Normo.+Azoo. mixture: 455. 1 minutes of average sperm motile time Group 4, Mixture of Oligospermia and Azoospermia; 6 mixtures Oligospermia: 343. 6 minutes of average sperm motile time Azoospermia: Oligo.+Azoo. mixture: 348. 1 minutes of average serum motile time In In conclusion, 1. no mutual spermicidal effect but tendency toward enhancement of sperm motile time 2. no sperm agglutinating phenomenon nor sperm immobilizing effect were noted in various semen mixtures 3. posibilities of clinical application such as AID arc considerable and 4. further studies are needed in conjunction with the serum autoimmune mechanism.
Azoospermia
;
Ejaculation
;
Humans*
;
Infertility, Male
;
Male
;
Oligospermia
;
Semen*
;
Sperm Immobilizing Agents
;
Sperm Maturation
;
Sperm Transport
;
Spermatogenesis
;
Spermatozoa*
3.Effect of lead chloride on spermatogenesis and sperm parameters in mice.
Antonio GRAÇA ; João RAMALHO-SANTOS ;
Asian Journal of Andrology 2004;6(3):237-241
AIMTo evaluate the effect of acute lead chloride exposure on testis and sperm parameters in mice.
METHODSPbCl2, 74 mg/kg, was daily administered to sexually mature male mice for 3 days and the effects on the testicular histology and ultrastructure as well as the motility and density of spermatozoa in cauda epididymis were observed. An additional group of mice were treated for 1-3 days and were allowed to recover for 32 days to determine the reversibility of lead-induced changes.
RESULTSThe testicular weight, seminiferous tubular diameter and sperm counts were significantly decreased following 3 days of PbCl2 treatment, but were unaffected by shorter-term exposures. The changes caused by lead are mostly reversible.
CONCLUSIONAcute lead chloride exposure injures the fertility parameters of male mice and the effects are partially reversible.
Animals ; Epididymis ; drug effects ; physiology ; Lead ; pharmacology ; Male ; Mice ; Microscopy, Electron ; Sexual Maturation ; Sperm Motility ; drug effects ; Spermatogenesis ; drug effects ; physiology ; Spermatozoa ; cytology ; drug effects ; ultrastructure
4.Cortisol and catecholamine in internal spermatic vein: are they toxic materials responsible for impairment of the spermatogenesis in varicocele?.
Myong Kwan CHO ; Hyun Woo KIM ; Se Chul KIM
Korean Journal of Fertility and Sterility 1991;18(2):237-240
No abstract available.
Hydrocortisone*
;
Spermatogenesis*
;
Varicocele*
;
Veins*
5.The Effect of Finasteride on Spermatogenesis in Rat.
Kyung Dae MIN ; Soo Bang RYU ; Kyu Yun AHN
Korean Journal of Urology 2000;41(7):878-884
No abstract available.
Animals
;
Finasteride*
;
Rats*
;
Spermatogenesis*
6.Hormonal Change and Spermatogenesis in Aging Male.
Korean Journal of Andrology 2000;18(1):7-13
No abstract available.
Aging*
;
Humans
;
Male*
;
Spermatogenesis*
7.FMRP: a new chapter with chromatin.
Protein & Cell 2014;5(12):885-888
Animals
;
Humans
;
Male
;
Spermatogenesis
8.Impact of glycosylation on the unimpaired functions of the sperm.
Yong Pil CHEON ; Chung Hoon KIM
Clinical and Experimental Reproductive Medicine 2015;42(3):77-85
One of the key factors of early development is the specification of competence between the oocyte and the sperm, which occurs during gametogenesis. However, the starting point, growth, and maturation for acquiring competence during spermatogenesis and oogenesis in mammals are very different. Spermatogenesis includes spermiogenesis, but such a metamorphosis is not observed during oogenesis. Glycosylation, a ubiquitous modification, is a preliminary requisite for distribution of the structural and functional components of spermatids for metamorphosis. In addition, glycosylation using epididymal or female genital secretory glycans is an important process for the sperm maturation, the acquisition of the potential for fertilization, and the acceleration of early embryo development. However, nonemzymatic unexpected covalent bonding of a carbohydrate and malglycosylation can result in falling fertility rates as shown in the diabetic male. So far, glycosylation during spermatogenesis and the dynamics of the plasma membrane in the process of capacitation and fertilization have been evaluated, and a powerful role of glycosylation in spermatogenesis and early development is also suggested by structural bioinformatics, functional genomics, and functional proteomics. Further understanding of glycosylation is needed to provide a better understanding of fertilization and embryo development and for the development of new diagnostic and therapeutic tools for infertility.
Acceleration
;
Birth Rate
;
Cell Membrane
;
Computational Biology
;
Embryonic Development
;
Female
;
Fertilization
;
Gametogenesis
;
Genomics
;
Glycosylation*
;
Humans
;
Infertility
;
Male
;
Mammals
;
Mental Competency
;
Oocytes
;
Oogenesis
;
Polysaccharides
;
Pregnancy
;
Proteomics
;
Sperm Maturation
;
Spermatids
;
Spermatogenesis
;
Spermatozoa*
9.The first Vietnamese baby born from intracytoplasmic sperm injection using testicular sperm from impaired spermatogenesis testes
Ho Chi Minh city Medical Association 2004;9(2):106-109
The first Viet Nam baby born from intracytoplasmic sperm injection using testicular sperm from impaired spermatogenesis testes in 1/3/2004. There was approximately 50000 sperm after preparation, among them 20% was motile. From 12 retrieved oocytes, 11 were mature and therefore injected. Five oocytes fertilized and developed into 4 embryos. Embryo transfer was carried out for all 4 embryos. One embryo implanted and kept growing till the 37th week of pregnancy. Patient underwent ceasarian section
Spermatogenesis
;
Sperm Retrieval
;
Sperm Injections, Intracytoplasmic
10.Effect of vasectomy via inguinal canal on spermatogenesis in rabbits.
Bin PENG ; Ya-Ping WANG ; Yi SHANG ; Yang GUO ; Zheng-Wei YANG
Asian Journal of Andrology 2008;10(3):486-493
AIMTo determine whether vasectomy away from the epididymal tail (via the inguinal canal) in rabbits can reduce the early postoperative effects on spermatogenesis.
METHODSTwenty-nine normal male Japanese white rabbits (aged 4-6 months) were subjected to unilateral close-ended (conventional) or open-ended (the cut end of the juxta-epididymal vas deferens not ligated) vasectomy via the inguinal canal. Ten days and 3 months after operation, testes, epididymides and vasa deferentia were removed and methacrylate resin-embedded sections prepared. The histology of the testis, epididymis and vas deferens was examined under light microscope, and the volume and diameter of the seminiferous tubules were quantitatively studied using stereological methods.
RESULTSNeither of the methods of vasectomy led to apparent damage to spermatogenesis on the vasectomized side in comparison with the contralateral sham-operated side, but the juxta-epididymal vas deferens on the vasectomized side was highly distended and contained numerous sperm 3 months after operation.
CONCLUSIONVasectomy away from the cauda epididymis has no significant early postoperative effects on spermatogenesis in rabbits.
Animals ; Male ; Rabbits ; Spermatogenesis ; Vasectomy ; methods