1.Oxidative Stress and Metabolic Syndrome.
Korean Journal of Family Medicine 2014;35(1):44-44
No abstract available.
Oxidative Stress*
2.The Effect of Estrogen on Antioxidant Enzymes in Bone of Oophorectomized Rats.
Young Do KOH ; Se In OH ; Mee Sook LEE ; Chang Mo KANG ; Chung Shil KWAK ; Sang Cheol SEONG ; Sang Chul PARK
The Journal of the Korean Orthopaedic Association 1998;33(1):148-157
The purpose of this study is to evaluate an antioxidative effect of estrogen on the bone in oophorectomized rats. Thirty Sprague-Daley rats were equally divided into 3 groups; group 1 as control group with sham operation, group 2 as experimental group with oophorectomy, and group 3 as oophorectomized group treated with estrogen. Estradiol (5mg/kg BW) was administered three times per week from first to sixth week after oophorectomy. Left tibia was obtained to measure the amount of protein carbonyls as an index of oxidative stress and the activity of antioxidant enzymes. The results were as follows: trahecular bone area in proximal tihia decreased after oophorectomy, which increased in response to estrogen administration. The level of protein carbonylation in hone was not significantly different among all groups. Activity of antioxidant enzymes such ais glutathione reductase(GR), glutathione peroxidase(GP) and glutathione transferase(GST) in bone was not significantly different among all groups. However, the activity of catalase in bone markedly increased in group 3 compared with that in group 1 and group 2. In summary, bone trabecular area increased after admin- istration of estrogen. And estrogen induced the activitv of catalase, which might contrihute to prevent the oxidative damage. However, the glutathione utilizing enzymes such as GR, GP and GST were not significantly affected by estrogen status.
Animals
;
Catalase
;
Estradiol
;
Estrogens*
;
Female
;
Glutathione
;
Ovariectomy
;
Oxidative Stress
;
Protein Carbonylation
;
Rats*
;
Tibia
4.Metabolic Syndrome and Oxidative Stress, Antioxidants.
Journal of the Korean Academy of Family Medicine 2006;27(10):773-781
No abstract available.
Antioxidants*
;
Oxidative Stress*
5.Oxidative Stress and Atherosclerosis.
Ha Young KIM ; Joong Yeol PARK
Journal of Korean Society of Endocrinology 2000;15(1):1-14
No abstract available.
Atherosclerosis*
;
Oxidative Stress*
6.Electroconvulsive Therapy and Oxidative Stress: Comment on the Article of Şenyurt et al. (Clin Psychophacol Neurosci 2017;15:40–46).
Tevfik KALELIOGLU ; Abdullah GENC ; Nesrin KARAMUSTAFALIOGLU
Clinical Psychopharmacology and Neuroscience 2017;15(3):298-299
No abstract available.
Electroconvulsive Therapy*
;
Oxidative Stress*
7.Exercise attenuates oxidative stress in patients with stroke
Nagatoshi Kihoin ; Kazunari Tanaka ; Masaaki Okuno ; Tadashi Okamoto ; Ryuichi Saura
Neurology Asia 2016;21(1):7-16
In stroke patients, excessive oxidative stress impairs brain nerve cells and leads to arteriosclerosis. On
the other hand, rehabilitative exercise is necessary for the functional improvement and maintenance
after stroke, and exercises themselves increase reactive oxygen species production simultaneously.
Therefore, it is essential to elucidate how exercises influence oxidative stress in stroke patients. We
assessed the effects of exercises on 29 Japanese subacute-phase stroke patients (exercise group, 20;
control group, 9), in terms of oxidative stress by examining changes in reactive oxygen metabolite
(ROM) level (i.e., oxidative stress) and biological antioxidant potential (BAP) level (i.e., antioxidant
capacity) in blood plasma. The exercise group performed two sets of 1-hour exercises 6 days/week for
56 days. The control group performed the same 1-hour exercises, but only on days 1 and 56. ROM and
BAP levels in blood plasma in both groups were measured immediately before and after the exercises
and at rest on days 1 and 56. ROM level significantly decreased and BAP level significantly increased
at rest from days 1 to 56 in the exercise group. However, no significant change was observed in these
levels in the control group.
Conclusion: Regular rehabilitative exercise can improve antioxidant capacity and attenuate oxidative
stress even in stroke patients.
Oxidative Stress
;
Stroke
;
Arteriosclerosis
8.Oxidative stress: link between hypertension and diabetes.
The Korean Journal of Internal Medicine 2017;32(3):439-441
No abstract available.
Hypertension*
;
Oxidative Stress*
9.Increased protein carbonyls as markers for oxidative stress in amniotic fluid of preeclamptic women at term.
Byoung Jae KIM ; Joong Shin PARK
Korean Journal of Obstetrics and Gynecology 2007;50(10):1354-1362
OBJECTIVE: To determine if the content of protein carbonyls in amniotic fluid is elevated in preeclamptic women at term. METHODS: A case-control study was conducted to compare contents of protein carbonyls in term amniotic fluid (gestational age at amniocentesis > or = 37 wks) among women who were healthy pregnant, preeclamptic and chronic hypertensive. Protein carbonyls were measured by specific immunoassay. Nonparametric techniques were used for statistical analysis. RESULTS: 1) The median amniotic fluid protein carbonyl of preeclamptic women was significantly higher than that of normal pregnant women (median 0.663 nmol/mg, range 0.013-1.726 nmol/mg vs. median 0.395 nmol/mg, range 0.069-1.503 nmol/mg, p<.05). 2) There was no significant difference in the amniotic fluid protein carbonyl level between women with chronic hypertension and normal pregnant women (median 0.823 nmol/mg, range 0.064-1.575 nmol/mg vs. median 0.395 nmol/mg, range 0.069-1.503 nmol/mg, p=.14). 3) The median amniotic fluid protein carbonyl showed tendency to increase with severity of preeclampsia without reaching statistical significance (normal pregnancy, median 0.395 nmol/mg, range 0.069-1.503 nmol/mg; mild preeclampsia, median 0.663 nmol/mg, range 0.013-1.054 nmol/mg; severe preeclampsia, median 0.842 nmol/mg, 0.391-1.726 nmol/mg; p=.07). The median protein carbonyl in amniotic fluid of women with severe preeclampsia was significantly higher than that of normal pregnant women (median 0.842 nmol/mg, range 0.391-1.726 nmol/mg vs. median 0.395 nmol/mg, range 0.069-1.503 nmol/mg, p<.05). CONCLUSIONS: The protein carbonyls increased in amniotic fluid of women with preeclampsia, but not chronic hypertension at term.
Amniocentesis
;
Amniotic Fluid*
;
Case-Control Studies
;
Female
;
Humans
;
Hypertension
;
Immunoassay
;
Oxidative Stress*
;
Pre-Eclampsia
;
Pregnancy
;
Pregnant Women
;
Protein Carbonylation
10.Paraoxonase Activity and Oxidative Status in Patients with Tinnitus.
Sema KOÇ ; Servet AKYÜZ ; Battal Tahsin SOMUK ; Harun SOYALIC ; Beyhan YILMAZ ; Abdullah TASKIN ; Hasan BILINC ; Nurten AKSOY
Journal of Audiology & Otology 2016;20(1):17-21
BACKGROUND AND OBJECTIVES: The aim of this study was to investigate serum paraoxanase-1 (PON) activity, total oxidant status (TOS), total antioxidant status (TAS), and the oxidative stress index (OSI) in tinnitus; and to compare the results with data from healthy subjects. SUBJECTS AND METHODS: A total of 114 subjects-54 patients with tinnitus and 60 healthy controls were enrolled in this study. Serum PON activity, TOS, TAS, and OSI levels were measured. RESULTS: In the tinnitus group, TAS, and PON were significantly lower than in the control group (p<0.001). However, the TOS, and OSI levels were significantly higher in the tinnitus group than in the control group (p<0.001). CONCLUSIONS: According to the data obtained from the present study, patients with tinnitus were exposed to potent oxidative stress. Oxidative stress may be the key contributing factor to the pathogenesis of tinnitus.
Aryldialkylphosphatase*
;
Humans
;
Oxidative Stress
;
Tinnitus*