The mechanical stiffness of Unilateral-Ring Hybrid External Fixation(URHEF) was analyzed and compared with conventional Ilizarov circular external fixation system and unilateral fixation with DynaExtor(R). Our URHEF is basically a unilateral external fixation system which affords easier incorporation and removal of the Ilizarov rings(200mm in diameter) coupled with connecting clamps at anytime, if needed. It allows controlled axial micromotion in due time. For mechanical test, URHEF system was constructed using a DynaExtor(R) fixed with two or three half pins(6 mm in diameter) attached with two proximal and distal Ilizarov rings fixed with an olive pin and a half pin on each ring. Unilateral fixation system was constructed with a DynaExtor(R) fixed with 2 or 3 half pins. Ring fixation system was constructed with four Ilizarov rings(140mm in diameter). Ilizarov system were assembled into 90degrees-90degrees and 45degrees-13 5degrees configurations with 2 olive pins, respectively. The distance between the center of pylon and the pin-clamp interface was equalized, being 70mm, in all the systems. Stiffness in axial compression, anteroposterior and lateral bending was measured. On axial compression and lateral bending tests, URHEF was stiffer than DynaExtor(R) and Ilizarov systems. On anteroposterior bending test, URHEF was less stiff than 90degrees-50degrees configuration of the Ilizarov system but stiffer than 45degrees-135degrees configuration. Considering the fact that instead of 90degrees-90degrees transfixing pin fixatin system, 45degrees-135degrees configuration system is generally used in clinical practice, URHEF appears to be significantly stiffer than unilateral(DynaExtor(R)) and circular (Ilizarov)fixation systems. This mechanical study implicates that URHEF can be beneficially applied in the clinical use with assurance of mechanical stability.
External Fixators ; Olea

The purpose of this study is to evaluate biomechanical stability of Korean Ilizarov fixator before clinical application. We measured the ultimate tensile load and stiffness of Ilizarov smooth wire and olive wire, bending stiffness of half-pin, ultimate compressive load and stiffness of Ilizarov ring using Instron 1331. Four types of Ilizarov assembly were tested for measuring stiffness of axial compression, anteroposterior bending, and lateral bending. There were group I fixed with only smooth wires; group II with only olive wires; group III with wires and half-pins; and group IV with only half-pins. The results of Korean Ilizarov apparatus were compared to those of American Ilizarov apparatus using unpaired t-test. The ultimate tensile strength of Korean smooth wire was greater than that of American wire. The ultimate tensile strength of Korean olive wire was lower than that of American wire. There was no significant difference of stiffness of axial compression, anteroposterior bending, and lateral bending between American and Korean apparatus. There was no significant difference of axial compression stiffness and bending stiffness between group III and group IV. In conclusion, Korean Ilizarov apparatus can be used with good stability for treatment of fracture, internal bone transport, and limb lengthening according to this biomechanical study.
Extremities ; Olea ; Tensile Strength

If the intramedullary nail fails for any reason, the broken nail must be removed by a closed or open manner to perform the next procedure for osteosynthesis. Numerous techniques have been introduced but the removal was difficult to do without special equipment. We have successfully removed the distal segment only with the olive tipped and straight guide rod which are ordinary equipment for intramedullary nailing. We found that this is a very simple, safe and economic method for retrieval of the distal fragment of broken femoral and tibial nails.
Femur* ; Fracture Fixation, Intramedullary ; Olea

The current study describes seven species that are new to the lichen mycota of South Korea. A taxonomic description of Arthonia excipienda, A. radiata, Arthothelium ruanum, Enterographa leucolyta, Fissurina elaiocarpa, Rinodina oleae, and Thelotrema porinaceum was given and supported by distribution, ecology, and illustrations. Each species was compared with a species showing close resemblance.
Classification ; Ecology ; Lichens* ; Olea ; Republic of Korea*

This study was undertaken to investigate the optimal conditions for challenge testing with DNCB in 3 vehicles applied to guinea pigs in standardized amount/ area (pg/cm2) The results are sumrnarized as follows: 1) All test reactions were negative when tested in 10 unsensitized animals. 2) There were significant difference in positive rate between 0. 05%, DNCB in alcohol and 0.1% DNCB in alcohol, but there were no significant difference between 0. l%, DNCB in alcohol and 0, 2% DNCB in alcohol. Same results were obtaincd when DNCR was dissolved in acetone. 3) Acetone gives the significantly higher degree of positive reactions, indicating that alcohol may be the safer vehicle in eliciting a response than acetone. 4) With DNCB in olive oil, relatively few animals reacted compared to the results obtained with alcohol and acetone. Furthermore, olive oil is slippery and difficult to utilize when attempting to delineate surface area. 5) With alcohol, we obtained a good correlation between the amount applied and the resulting response, showing that this vehicle might be a superior vehicle in eliciting contact allergy.
Acetone ; Animals ; Dinitrochlorobenzene* ; Guinea Pigs* ; Guinea* ; Hypersensitivity* ; Olea ; Olive Oil

A typical case of collodion baby was reported. On admission, the entire skin surface of this infant was covered with collodion-like membrane with fissures and exfoliations. Flexion contracture of all four extrimities and ectropion of both eyes were also appeared on admission. The family history and laboratory findings were unremarkable. The skin lesions were almost completely healed after application of copious amount of Vit. A cream; Prednisolone ointment and Olive oil for one month. A brief review of literatures were presented.
Collodion* ; Contracture ; Ectropion ; Humans ; Infant ; Membranes ; Olea ; Prednisolone ; Skin

PURPOSE: Wingspan is the only FDA approved self-expanding stent for intracranial artery and known to have better delivery compared to balloon expandable stent. However, some delivery failure has been reported but incidence and mechanism of the failure have not been completely elucidated. We present the cause and mechanism of Wingspan deployment failure experienced in our Institute. MATERIALS AND METHODS: We experienced deployment failure in seven patients (8.8%) out of 80 patients who underwent Wingspan stenting since 2007. Mean age of the patients was 62 (range 47~78) and male to female ratio was 6:1. We evaluated the cause and mechanism why the deployment was not successful and how we could manage it subsequently. RESULTS: We categorized failures occurred in seven patients into three categories: delivery failure (n = 3), deployment failure of stent (n = 3), retrieval failure of dual tapered (olive) tip of the inner body through the deployed the stent (n = 1). The technical failure in using Wingspan stent (delivery, deployment and retrieval failures) are related to tortuousness of the proximal (n =4) as well as distal (n =1) cerebral vessels to the stenotic lesion and bulky profile of the olive tip (n =2). CONCLUSION: The technical failure in using Wingspan stent (delivery, deployment and retrieval failures) are related to tortuousness of the proximal as well as distal cerebral vessels to the stenotic lesion and bulky profile of the olive tip. To avoid device-related complication, complete understanding of the stent design is mandatory before using the stent.
Arteries ; Atherosclerosis ; Female ; Humans ; Incidence ; Male ; Olea ; Stents

Hypertrophic olivary degeneration is usually caused by a lesion in the triangle of Guillain and Mollaret. The inciting pathology includes ischemic, inflammatory, degenerative or, less frequently, traumatic lesions. Clinically, it is usually accompanied by palatal myoclonus or other forms of segmental myoclonus. We present four patients with hypertrophic olivary degeneration studied with MRI after severe head trauma. MRI was performed between 5 and 18 months respectively after trauma. Although post-traumatic tremor was observed in three patients, none of patients showed palatal myoclonus. MRI showed multiple post-traumatic lesions within the dentato-rubro-olivary pathway associated with enlargement and increased signal intensity of the inferior olives.
Craniocerebral Trauma ; Humans ; Magnetic Resonance Imaging ; Myoclonus ; Olea ; Pathology ; Tremor

BACKGROUND: Although numerous culture conditions for Malassezia species were suggested, there were not so many objective evaluation articles in the literature. OBJECTIVES: We examined the various culture conditions for Malassezia globosa. METHODS: Malassezia globosa culture conditions were assessed by Dixon's agar, modified Leeming-Notman medium in diverse oil content and temperature conditions. RESULTS: Maximum growth rate of Malassezia globosa was achieved at 3% olive oil. The optimal temperatures for the maximal growth of M. globosa were observed at 32~34degrees C. CONCLUSION: In this study, we established the optimal culture condition for M. globosa, and confirmed its excellent utility for the antifungal susceptibility tests for M. globosa and M. restricta. Our results can help the investigators plan to do the prospective researches involving Malassezia species, such as the susceptibility test for newly developed antifungal agents.
Agar ; Antifungal Agents ; Humans ; Malassezia ; Olea ; Olive Oil ; Plant Oils ; Research Personnel

BACKGROUND/AIMS: This study was designed to determine the effect of hepatic fibrotic severity on pharmacokinetics of propranolol in CCl4-treated rats. METHODS: 1 mL/kg of 10% CCl4 in olive oil was injected intramuscularly to rats twice weekly for 4, 6, 8 and 10 weeks, respectively (n=6). Control (n=6) was a sham-injected equal dose of olive oil for 10 weeks. After intravenous bolus injection of 2 mg/kg propranolol to rats, the serum propranolol concentrations were analyzed for 4 hours at various time points by a HPLC-fluorimetric system, and pharmacokinetic parameters such as C0, MRT, AUC, Vdss, t1/2( ) and CLp were determined. Then, a small amount of hepatic tissue was obtained and subjected to determination of the hepatic 4-hydroxyproline content, which confirmed the hepatic fibrotic severity. RESULTS: The serum concentrations of propranolol at 0.5, 1, 2 and 4 hours were significantly increased in CCl4-treated rats (p<0.01). In proportion to the duration of CCl4 treatment, C0 and AUC were significantly increased, and Vdss and CLp were significantly decreased (p<0.001). But MRT and t1/2( ) were not significantly changed. The hepatic 4-hydroxyproline content was gradually increased in CCl4-treated rats (p<0.001). CONCLUSION: Gradual changes in pharmacokinetic parameters of propranolol were seen to be dependent on the hepatic fibrotic severity. We suggest that gradual dosage modification, according to their hepatic fibrotic severity, is necessary for many drugs administered to patients with chronic liver disease.
Animals ; Area Under Curve ; Humans ; Hydroxyproline ; Liver Diseases ; Olea ; Pharmacokinetics ; Propranolol* ; Rats* ; Olive Oil