Halo nevus is a pigmented nevus surrounded by acquired round depigmentation. Depigmentation appears mostly around several types of pigmented lesions, such as acquired nevus, congenital nevus, blue nevus and Spitz nevus. In contrast, it is rare that depigmentation develops around a congenital nevus. While the precise etiology of halo nevus and vitiligo remains uncertain, several theories suggest that both phenomena result from an immunologic reaction to melanocytes by CD8 + T cell. We report a case of halo congenital nevus in the arm, which is followed by periocular vitiligo. This is the third case in Korean dermatological literature.
Arm ; Melanocytes ; Nevus ; Nevus, Blue ; Nevus, Epithelioid and Spindle Cell ; Nevus, Halo ; Nevus, Pigmented ; Vitiligo

Blue nevus is a benign pigmented lesion of dermal melanocytes with a number of histologic and clinical variants. We report a variant of cellular blue nevus that is minimally pigmented. Immunohistochemistry showed the case to be strongly positive with S-100 protein, but negative with Ki-67 and HMB-45 antibody. There is a potential for hypopigmented cellular blue nevus to be confused with other benign nevus, such as intradermal nevus, Spitz nevus, and deep penetrating nevus and malignant melanoma.
Immunohistochemistry ; Melanocytes ; Melanoma ; Nevus ; Nevus, Blue* ; Nevus, Epithelioid and Spindle Cell ; Nevus, Intradermal ; S100 Proteins

Benign pigmented lesions derived from dermal melanocytes include the Mongolian spot, the nevi of Ota and Ito, and the blue nevus. The nevus of Ito differs from the nevus of Ota by its location in the supraclavicular, scapular and deltoid regions. It occurs rarely in association with bilateral nevus of Ota. We present a 70 years old male, showing extensive involvement of dermal melanocytic nevi, so called bilateral nevus of Ota associated with bilateral nevus of Ito.
Aged ; Humans ; Male ; Melanocytes ; Mongolian Spot ; Nevus of Ota* ; Nevus* ; Nevus, Blue ; Nevus, Pigmented

A nevus with cyst is defined as a single lesion of a melanocytic nevus, and this is commonly associated with an epidermal cyst. For the previously reported cases of a nevus with cyst, most of the melanocytic nevi were of the intradermal or compound type. There have been rare reported cases of dysplastic nevus, blue nevus, Spitz nevus, congenital melanocytic nevus and so forth. We report here on a rare case of congenital melanocytic nevus combined with an epidermal cyst in a 21-year-old woman.
Dysplastic Nevus Syndrome ; Epidermal Cyst ; Female ; Humans ; Nevus ; Nevus, Blue ; Nevus, Epithelioid and Spindle Cell ; Nevus, Pigmented ; Young Adult

Congenital giant melanocytic nevi (CGMN) are lesions of more than 20 cm in diameter, often in the distribution of a garment. Depigmented zones may appear around several types of acquired lesions such as dermal, junctional, and compound nevi, Spitz nevus, blue nevus, and malignant melanoma. The depigmentation may occur within the lesion, around it, or at a distant site. In contrast, congenital nevi rarely develop depigmentation. Vitiligo-like leukoderma distant from the nevus has developed in only three cases with a CGMN. We report two cases of CGMN with vitiligo which is located away from primary CGMN lesion.
Melanoma ; Nevus ; Nevus, Blue ; Nevus, Epithelioid and Spindle Cell ; Nevus, Pigmented* ; Vitiligo*

Deep penetrating nevus is a recently described variant of melanocytic nevi. It's clinical and histopathological features can be confused with malignant melanoma, blue nevus, Spitz nevus, pigmented spindle cell nevus, or congenital melanocytic nevus. Histopathologically, the lesions are characterized by loosely-organized nests of slightly to distinctively pleomorphic pigmented cells which deeply penetrate the reticular dermis and often extend into the subcutis. We report a case of deep penetrating nevus on the right arm of a 21-year-old female.
Arm ; Dermis ; Female ; Humans ; Melanoma ; Nevus* ; Nevus, Blue ; Nevus, Epithelioid and Spindle Cell ; Nevus, Pigmented ; Nevus, Spindle Cell ; Young Adult

Deep penetrating nevus (DPN) is a distinctive melanocytic nevus firstly reported by Seab et al. in 1989. It is characterized by its dark pigmentation, occurring mostly on the face, neck, or shoulder, and usually measures less than 1 cm in diameter. Since it has histologic similarities with other cutaneous pigmented lesions such as combined nevus, blue nevus, Spitz nevus, and pigmented spindle cell nevus, it is often difficult to diagnose and it may be clinically and histologically mistaken for a malignant melanoma. There have been 2 reported cases of DPN in the Korean dermatologic literatures; therefore, we report a case of DPN mimicking malignant melanoma.
Melanoma ; NAD ; Neck ; Nevus ; Nevus, Blue ; Nevus, Epithelioid and Spindle Cell ; Nevus, Pigmented ; Nevus, Spindle Cell ; Pigmentation ; Shoulder

A halo nevus is a pigmented nevus surrounded by a depigmented zone. It usually occurs in childhood or adolescence. Depigmented zone may form around a variety of acquired melanocytic lesions of neuroectodermal origin, including nevocellular nevi, blue nevi, spindle and epithelioid nevi, primary and metastatic melanomas, and neurofibromas. The occurrence of a halo around congenital melanocytic nevi has rarely been reported. We report a case of halo congenital nevus in a 11-year-old girl.
Adolescent ; Child ; Female ; Humans ; Melanoma ; Neural Plate ; Neurofibroma ; Nevus* ; Nevus, Blue ; Nevus, Halo ; Nevus, Pigmented

No abstract available.
Mongolian Spot* ; Nevus, Blue*

Dermal melanocytosis is characterized by the presence of ectopic melanocytes in the dermis. The most common forms include the Mongolian spot, blue nevus, nevus of Ota, and nevus of Ito. Some types of dermal melanocytosis do not fit into any of these morphologic categories, however. Our case demonstrated an extensive amount of uniform deep blue patches of nevi with unilateral distribution on the left face, neck, chest, shoulder, and back. On histopathologic examination, a number of elongated melanocytes scattered throughout the dermis were found. We herein report a case of congenital unilateral dermal melanocytosis.
Dermis ; Melanocytes ; Mongolian Spot ; Neck ; Nevus ; Nevus of Ota ; Nevus, Blue ; Shoulder ; Thorax