1.Hansen's fingerprints in bone marrow histiocytes.
Blood Research 2016;51(2):76-76
No abstract available.
Bone Marrow*
;
Dermatoglyphics*
;
Histiocytes*
2.Recent Updates in Langerhans Cell Histiocytosis
Kyung Nam KOH ; Ho Joon IM ; Jong Jin SEO
Clinical Pediatric Hematology-Oncology 2015;22(1):15-21
Langerhans cell histiocytosis (LCH) encompasses a wide range of clinical presentation and its clinical course varies widely from spontaneous regression to severe disseminated disease with the risk of permanent consequences. Although pathogenesis of LCH has been a conundrum, recent advances have led to a better understanding of the molecular pathogenesis of the disease. Especially, advanced genomic analyses have suggested that LCH is a disorder of MAPK pathway mutations. Optimal treatment for LCH has not been established yet. Histiocyte Society has launched a new international multi-center clinical trial, LCH-IV to solve remaining major issues in the treatment of LCH. The aim of this review is to provide an overview of recent understandings on the pathogenesis and treatment of LCH.
Histiocytes
;
Histiocytosis, Langerhans-Cell
3.Retroperitoneal Malignant Fibrous Histiocytoma: Report of a Case.
Sang Hoon KIM ; Woong Yong JIN ; Mee Kyung HUH ; Dae Haeng CHO ; Moon Soo YOON
Korean Journal of Urology 1986;27(2):305-308
Malignant fibrous histiocytoma is an uncommon pleomorphic tumor of the soft tissues possibly arising from the histiocyte. A case of huge malignant fibrous histiocytoma weighing 10.2kg in the retroperitoneal space is reported with brief review of literatures.
Histiocytes
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Histiocytoma
;
Histiocytoma, Malignant Fibrous*
;
Retroperitoneal Space
4.A Case of Xanthogranuloma on the Concha of the Ear in an Adolescent.
Eun LEE ; Jung Eun KIM ; Hyun Jeong PARK ; Jun Young LEE ; Baik Kee CHO
Korean Journal of Dermatology 2009;47(8):976-978
A xanthogranuloma is a self-limiting, benign disorder that is caused by the proliferation of histiocytes. It usually develops on the face, scalp, and upper extremities, but rarely develops in the ear. Only two cases of xanthogranuloma of the ear have been reported in the literature. We present a xanthogranuloma on the concha of the Lt. ear in a 14-year-old boy.
Adolescent
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Ear
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Histiocytes
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Humans
;
Scalp
;
Upper Extremity
5.A Case of Multiple Xanthogranuloma in an Adult.
Sang Soon KIM ; Young Ran YOON ; Woo Young SIM ; Mu Hyoung LEE ; Choong Rim HAW
Korean Journal of Dermatology 1990;28(5):656-659
We report a case of multiple xanthogranuloma occurring ori the scalp in a 33 years old wornan. Multiple yellowish papules were developed on her scalp 3 months ago. Histopathologic findings showed massive granulomatous infiltrations of foamy histiocytes Touton giant cells in the dermis, and these cells were positive for lipid stain. This case was considered to be multiple xanthogranuloma in an adult, and treated by sur- gical excision.
Adult*
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Dermis
;
Giant Cells
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Histiocytes
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Humans
;
Scalp
6.A Case of Niemann-Pick Disease with Sea-Blue histiocytes in the Bone Marrow.
Young Sun KIM ; Soo Heum LIM ; Jeong Kee SEO ; Hyo Seop AHN ; Hyung Ro MOON
Journal of the Korean Pediatric Society 1985;28(12):1238-1244
No abstract available.
Bone Marrow*
;
Histiocytes*
;
Niemann-Pick Diseases*
7.A Case of Multiple Adult Xanthogranulomas.
Yong Kwan RHO ; Yeon Jin KIM ; Ji Young AHN ; Seong Jun SEO ; Chang Kwun HONG ; Kye Yong SONG
Korean Journal of Dermatology 2007;45(11):1176-1179
Adult xanthogranuloma is nearly indistinguishable from juvenile xanthogranuloma characterized by yellow-red nodules on the skin, normal lipid findings and the proliferation of xanthomatizied histiocytes with foamy Touton cells, histologically. But unlike juvenile xanthogranuloma, there is no visceral involvement, spontaneous regression and more solitary lesions. Multiple adult xanthogranulomas are rare entities that present more spontaneous involution. Here we report a case of a 39-year-old patient with multiple xanthogranulomas which developed on the face, trunk and extremities. Diagnostic workup revealed normal lipid profile and no extracutaneous manifestations.
Adult*
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Extremities
;
Histiocytes
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Humans
;
Skin
;
Xanthogranuloma, Juvenile
8.A Case of the retroperitoneal Malignant Fibrous Histiocytoma.
Bog Ho SHIN ; In CHOI ; Hyun Jae NA ; Hak Young LEE ; Young Nam WOO ; Dong Han KIM
Korean Journal of Urology 1982;23(4):569-572
Malignant fibrous histiocytoma is uncommon pleomorphic tumor of the soft tissues possibly arising from the histiocyte. A case of malignant fibrous histiocytoma of the retroperitoneum stimulated our interest in this uncommon and pathologically intriguing lesion. So we report a case of malignant fibrous histiocytoma in the retroperitoneal space.
Histiocytes
;
Histiocytoma
;
Histiocytoma, Malignant Fibrous*
;
Retroperitoneal Space
9.Cutaneous Rosai-Dorfman disease.
Joon Joon Khoo ; Bin Othman Rahmat
The Malaysian journal of pathology 2007;29(1):49-52
Rosai-Dorfman disease (RDD) is a rare benign proliferative disorder of histiocytes in the lymph nodes with or without extranodal involvement. RDD limited to the skin without nodal involvement, known as cutaneous Rosai-Dorfman disease, is very rare. We describe a 34-year-old female with RDD of the skin over the chest. A large nodule with satellite lesions was excised for histopathological examination. Microscopically, there were many large histiocytes (Rosai-Dorfman cells) exhibiting emperipolesis, among many plasma cells, lymphocytes and neutrophils throughout the dermis and the subcutaneous tissue. The histiocytes were immunohistochemically positive for S-100 protein but negative for CD 1a. Physical examination showed no lymphadenopathy or any extra-cutaneous lesions. Serological tests indicated a past infection with Epstein-Barr virus and cytomegalovirus. The diagnosis of cutaneous RDD may be difficult in the absence of associated lymphadenopathy or any specific features of the skin lesion. Hence, not only is histopathological examination required for definitive diagnosis but a high index of suspicion by the clinicians and pathologists is essential to help diagnose this very rare disease.
seconds
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Cutaneous
;
Histiocytes
;
Enlargement of lymph nodes
;
Diagnostic
10.A case of cutaneous tuberculosis presenting with generalized xanthogranulomas.
Leah Antoinette M. CARO-CHANG ; Eileen Liesl A. CUBILLAN
Acta Medica Philippina 2019;53(2):181-185
A 33-year-old male had a 22-year history of generalized xanthogranulomas but had a normal lipid profile. He also developed ulcerating plaques on his arm and back that were consistent with cutaneous tuberculosis on histopathologic and polymerase chain reaction PCR studies. In a normolipemic patient with generalized xanthogranulomas, a reactive granulomatous response of histiocytes to infection is explored since these share a common CD 14+ precursor with the macrophages that are vital in tuberculosis.
Human ; Tuberculosis ; Histiocytes ; Tuberculosis, Cutaneous ; Xanthomatosis