1.Protein Transplantation : Its Significance in Biology and Medicine.
Journal of the Korean Medical Association 2000;43(1):45-49
No abstract available.
Biology*
2.Integration of Craniofacial Biology to Find Creative Solutions in Clinical Cases: Is the ‘Biology’ Ready for Translation?
Journal of Korean Dental Science 2019;12(1):1-4
No abstract available.
Biology
3.Biology of Eosinophile.
Tuberculosis and Respiratory Diseases 1998;45(2):259-270
No abstract available.
Biology*
;
Eosinophils*
4.Molecular Genetic Assessment of Benign and Borderline Tumors as Precursor Lesions of Epithelial Ovarian Carcinoma.
Joo Hyun NAM ; Jong Hyuk KIM ; Joo Ryung HUR ; Gun Goo PARK ; Yong Man KIM ; Young Tak KIM ; Jung Eun MOK ; Soon Bum KANG
Korean Journal of Obstetrics and Gynecology 2000;43(12):2220-2230
No abstract available.
Molecular Biology*
5.A Heuristic Algorithm to Find All Normalized Local Alignments Above Threshold.
Sangtae KIM ; Jeong Seop SIM ; Heejin PARK ; Kunsoo PARK ; Hyunseok PARK ; Jeong Sun SEO
Genomics & Informatics 2003;1(1):25-31
Local alignment is an important task in molecular biology to see if two sequences contain regions that are similar. The most popular approach to local alignment is the use of dynamic programming due to Smith and Waterman, but the alignment reported by the Smith-Waterman algorithm has some undesirable properties. The recent approach to fix these problems is to use the notion of normalized scores for local alignments by Arslan, Egecioglu and Pevzner. In this paper we consider the problem of finding all local alignments whose normalized scores are above a given threshold, and present a fast heuristic algorithm. Our algorithm is 180-330 times faster than Arslan et al.''s for sequences of length about 120 kbp and about 40-50 times faster for sequences of length about 30 kbp.
Molecular Biology
6.Molecular analysis of childhood acute lekemia.
Hack Ki KIM ; Kyong Su LEE ; Sung Hoon CHO ; Du Bong LEE
Journal of the Korean Pediatric Society 1991;34(2):164-171
No abstract available.
Molecular Biology
7.Proteomics
Journal of Preventive Medicine 2001;11(4):55-60
In the 21st century, proteomics, a new science, appears in the biology. Proteomics studies the human protein, opens a new era of molecular pathology. The scientists suggest that the human being is determined by 2 factors: the genetic system or human genome and various influences of surrounding environment. From which, proteomics have been become the turning point of the biology at the beginning of 21st century.
Proteomics
;
Biology
8.Java DOM Parsers to Convert KGML into SBML and BioPAX Common Exchange Formats.
Kyung Eun LEE ; Myung Ha JANG ; Arang RHIE ; Chin Ting THONG ; Sanduk YANG ; Hyun Seok PARK
Genomics & Informatics 2010;8(2):94-96
Integrating various pathway data collections to create new biological knowledge is a challenge, for which novel computational tools play a key role. For this purpose, we developed the Java-based conversion modules KGML2SBML and KGML2BioPAX to translate KGML (KEGG Markup Language) into a couple of common data exchange formats: SBML (Systems Biology Markup Language) and BioPAX (Biological Pathway Exchange). We hope that our work will be beneficial for other Java developers when they extend their bioinformatics system into SBML- or BioPAX-aware analysis tools. This is part of our ongoing effort to develop an ultimate KEGG-based pathway enrichment analysis system.
2,5-Dimethoxy-4-Methylamphetamine
;
Biology
;
Computational Biology
;
Indonesia
;
Systems Biology
9.Parsing KEGG XML Files to Find Shared and Duplicate Compounds Contained in Metabolic Pathway Maps: A Graph-Theoretical Perspective.
Sung Hui KANG ; Myung Ha JANG ; Jiyoung WHANG ; Hyun Seok PARK
Genomics & Informatics 2008;6(3):147-152
The basic graph layout technique, one of many visualization techniques, deals with the problem of positioning vertices in a way to maximize some measure of desirability in a graph. The technique is becoming critically important for further development of the field of systems biology. However, applying the appropriate automatic graph layout techniques to the genomic scale flow of metabolism requires an understanding of the characteristics and patterns of duplicate and shared vertices, which is crucial for bioinformatics software developers. In this paper, we provide the results of parsing KEGG XML files from a graph-theoretical perspective, for future research in the area of automatic layout techniques in biological pathway domains.
Computational Biology
;
Metabolic Networks and Pathways
;
Systems Biology
10.Molecular Targets for Treatment of Breast Cancer.
Woo Chan PARK ; Lee Su KIM ; Tae Hyun KIM ; Byeong Woo PARK ; Ho Yong PARK ; Byung Joo SONG ; Jae Bok LEE ; Chang Wan JEON ; Un Jong CHOI
Journal of Breast Cancer 2009;12(4):229-234
Advances in molecular biology have made it possible to understand the tumor biology of breast cancer at the molecular level and have revealed molecular targets for the therapy of breast cancer. Nowadays, targeting agents are used as mono-therapy or as combined therapy with other anti-cancer drugs for the treatment of breast cancer. Much more efforts is also being made in the development of better therapeutic agents targeting molecules having an important role in tumor biology. In this article, promising molecules for targeted therapy are reviewed for their roles in the pathophysiology and the treatment of breast cancer. We also introduce and summarize new preclinical agents, developed or on developing, with preliminary results from clinical trials. Given the progress currently being made, targeted therapy could become a main strategy for the treatment of breast cancer in the near future.
Biology
;
Breast
;
Breast Neoplasms
;
Molecular Biology