1.A Heuristic Algorithm to Find All Normalized Local Alignments Above Threshold.
Sangtae KIM ; Jeong Seop SIM ; Heejin PARK ; Kunsoo PARK ; Hyunseok PARK ; Jeong Sun SEO
Genomics & Informatics 2003;1(1):25-31
Local alignment is an important task in molecular biology to see if two sequences contain regions that are similar. The most popular approach to local alignment is the use of dynamic programming due to Smith and Waterman, but the alignment reported by the Smith-Waterman algorithm has some undesirable properties. The recent approach to fix these problems is to use the notion of normalized scores for local alignments by Arslan, Egecioglu and Pevzner. In this paper we consider the problem of finding all local alignments whose normalized scores are above a given threshold, and present a fast heuristic algorithm. Our algorithm is 180-330 times faster than Arslan et al.''s for sequences of length about 120 kbp and about 40-50 times faster for sequences of length about 30 kbp.
Molecular Biology
2.Molecular analysis of childhood acute lekemia.
Hack Ki KIM ; Kyong Su LEE ; Sung Hoon CHO ; Du Bong LEE
Journal of the Korean Pediatric Society 1991;34(2):164-171
No abstract available.
Molecular Biology
3.Molecular Genetic Assessment of Benign and Borderline Tumors as Precursor Lesions of Epithelial Ovarian Carcinoma.
Joo Hyun NAM ; Jong Hyuk KIM ; Joo Ryung HUR ; Gun Goo PARK ; Yong Man KIM ; Young Tak KIM ; Jung Eun MOK ; Soon Bum KANG
Korean Journal of Obstetrics and Gynecology 2000;43(12):2220-2230
No abstract available.
Molecular Biology*
4.Molecular genetic analysis of non-transferable antimicrobial resistance of shigella isolates.
Sung Yong SEOL ; Young Chul KWON ; Je Chul LEE ; Yoo Chul LEE ; Dong Taek CHO
Journal of the Korean Society for Microbiology 1992;27(2):125-141
No abstract available.
Molecular Biology*
;
Shigella*
5.Molecular Genetics of Diabetes Mellitus.
Journal of Korean Society of Pediatric Endocrinology 2001;6(2):114-117
No abstract available.
Diabetes Mellitus*
;
Molecular Biology*
6.Molecular Genetics on the Hereditary Neurodegenerative Disorders caused by Trinucleotide Expansion.
Journal of the Korean Pediatric Society 1996;39(7):894-900
No abstract available.
Molecular Biology*
;
Neurodegenerative Diseases*
7.Recent advances in molecular genetics of pediatric leukemias.
Journal of the Korean Pediatric Society 1993;36(5):605-614
No abstract available.
Leukemia*
;
Molecular Biology*
8.Molecular Biology of Atherosclerosis.
Endocrinology and Metabolism 2010;25(3):166-170
No abstract available.
Atherosclerosis
;
Molecular Biology
9.Cell and Molecular Biology of Medicine and Cardiovascular System in Normal and Diseases.
Korean Circulation Journal 1992;22(2):207-218
No abstract available.
Cardiovascular System*
;
Molecular Biology*
10.Future Development of Interbody Fusion Cages.
Ki Tack KIM ; Kyung Soo SUK ; Jin Moon KIM
Journal of Korean Society of Spine Surgery 2001;8(3):386-491
Interbody fusion using cages are becoming the popular procedure for the spinal fusion. To see the future of cages for interbody fusion, the current authors described history of interbody fusion and cages, biomechanics of cages, and kinds and problems of currently available cages. Based on the review of cages in the past and the present, current authors described requirements of future cages and future of the cages. Spinal fusion including interbody fusion using cages will exist as a major part of spinal surgery in the future. Development of surgical technique, medical engineering, and molecular biology will bring better outcome of interbody fusion.
Molecular Biology
;
Spinal Fusion