1.Successful delayed-interval delivery in the presence of clinical chorioamnionitis in the leading twin: A report of two cases
Shobini Sukumaran ; Devendra Kanagalingam
The Medical Journal of Malaysia 2019;74(1):85-86
We present two cases of diamniotic, dichorionic twin
pregnancies in which after the loss of the first foetus in the
setting of clinical chorioamnionitis, both pregnancies were
successfully managed by delayed-interval delivery. A fourstage protocol including aspects of management in this
specific setting is proposed. We consider the importance of
a selection process when managing conservatively,
measures to promote latency and decisions regarding
delivery of the foetuses. Whilst we report successful case
studies of conservative management with delayed-interval
delivery, we support a cautious approach and understand
that in the setting of clinical chorioamnionitis of the
remaining foetus, delivery is necessary.
2.Large falcine meningioma presented as treatmentresistant depression: A case report
Sim Sze Kiat ; Khairul Aizad Bin Adzman ; Lim Swee San ; Albert Hieng Sii Wong
The Medical Journal of Malaysia 2019;74(1):87-89
Large intracranial tumour may present only with psychiatric
symptoms without any neurological deficits. Delay in
surgical treatment may significantly affect the quality of life
in these patients. We report a case of a young engineering
student who was diagnosed as treatment-resistant
depression without initial neuroimaging study. Further
neuroimaging studies revealed he has a large falcine
meningioma. His psychiatric symptoms resolved following
surgical resection of the tumour. We emphasized the
importance of initial neuroimaging study in young patients
presenting with psychiatric symptoms.
3.Paediatric burkitt lymphoma presenting as a mandible swelling and intussusception
Senthilraj Retinasekharan ; Periyathamby Sinnathamby ; Irfan Mohamad
The Medical Journal of Malaysia 2019;74(1):90-
Burkitt lymphoma is a rare entity especially in this part of the
world. We had an 11-year-old patient presented with swelling
of the mandible for a short one-month duration. He was
planned for excision biopsy. However developed severe
abdominal pain while in the hospital and was diagnosed as
intussusception after ultrasound was done. We proceeded
with right hemicolectomy and excision of buccal mass. Early
recognition and close monitoring of insidious jaw lesions is
recommended even in young adults not within the modal
age category of endemic Burkitt.
4.Case series of testicular adrenal rest tumours in boys with congenital adrenal hyperplasia: A single centre experience
Karen Sue Wan Leong ; Loo Ling Wu
The Medical Journal of Malaysia 2019;74(1):92-93
Testicular adrenal rest tumours (TART) are aberrant adrenal
tissue within the testes (1). Although benign, they can lead
to obstruction of the seminiferous tubules and infertility in
patients with congenital adrenal hyperplasia (CAH). We
report six boys who developed TART, a complication of CAH.
Diagnosis was confirmed by ultrasound and testicular vein
sampling of elevated 17-hydroxyprogesterone (17-OHP)
levels. Glucocorticoids dosages were increased 1½-2 folds
to suppress size of the aberrant adrenal tissues. Despite
reductions in 17-OHP, the lesions remained unchanged.
Three patients had testis-sparing surgery to excise the TART
and to preserve normal testicular tissues.
5.Single stage treatment of complex aortic pathology (megaaortic syndrome) using frozen elephant trunk technique
Paneer Selvam Krishna Moorthy ; Sharul Akmal Saat ; Abd Samad Sakijan,
The Medical Journal of Malaysia 2019;74(1):94-96
This is a case report of single-stage total thoracic aortic
repair by the frozen elephant trunk technique for a 75-yearold female with a complex aortic pathology of mega-aorta
extending from the ascending aorta to the descending aorta.
We used a Thora flex™ Hybrid device, a frozen elephant
trunk device with four branched grafts and the distal stent
graft. The distal stent graft was inserted into the
downstream descending aorta via an aortic arch and
positioned 15 cm beyond the left subclavian artery after total
arch replacement had been performed using a four-branch
graft. The postoperative course was unremarkable with no
complications. A post procedural computed tomography
scan demonstrated complete exclusion of the descending
thoracic aneurysm without endoleak. Therefore, fixing the
whole mega-aorta in a single stage using the frozen elephant
trunk was effective and safe.
6.Paraneoplastic relapsing minimal change disease associated with type A thymoma in an elderly patient: A case report and literature review
Clara Lee Ying Ngoh ; Giap Hean Shaun Goh ; Weng Kin Wong
The Medical Journal of Malaysia 2019;74(1):97-98
Thymoma is a rare mediastinal tumour that can be
accompanied by different paraneoplastic syndromes. Here
we report a case of Type A thymoma associated with
relapsing minimal change disease (MCD). This case
highlights: (1) The need to balance rapid prednisolone
weaning against risk for relapse in an elderly patient at risk
for steroid-induced complications. (2) The addition of
calcineurin inhibitor in relapsed thymoma-related MCD, to
achieve steroid sparing effects. Resection of the offending
tumour and prompt immunosuppressive therapy are critical
in getting best renal and overall outcomes in this rare entity
7.Spontaneous massive haemothorax in the peri-partum period of an undiagnosed neurofibromatosis type 1 patient - A surgical perspective
Narasimman Sathiamurthy ; Hari Dass Govindasamy ; Kanesh Kumaran Kumaran Seevalingam ; Umasangar Ramasamy ; Ganendra Paramasvaran
The Medical Journal of Malaysia 2019;74(1):99-
Acute massive haemothorax is a life-threatening situation,
which is often associated with a preceding trauma. However,
spontaneous haemothorax is a rare occurrence, especially in
pregnancy. Spontaneous haemothorax in the immediate
post-partum period secondary to a ruptured intercostal AVM
is extremely rare more so in the background of an
undiagnosed neurofibromatosis. This is a report of a young
lady presenting with pleuritis and breathlessness after the
delivery of her 1st child. Her management is discussed.
8.Depression and potential risk factors among the elderly with Type 2 Diabetes Mellitus in Kedah, Malaysia
Azniza Muhamad Radzi ; Nani Draman ; Siti Suhaila Mohd Yusoff ; Rosediani Muhamad,
The Medical Journal of Malaysia 2019;74(2):103-108
Objective: Elderly with diabetes has been found to have a
higher chance of depression. Therefore, the aim of this
study is to determine the prevalence of depression and its
associated factors among elderly with Type 2 Diabetes
Mellitus in Kedah.
Methods: A cross-sectional study was conducted at the
Klinik Kesihatan Bandar, Sungai Petani, Kedah. The
inclusion criteria were patients aged ≥60 years with Type 2
Diabetes Mellitus. Those with cognitive impairment,
presence of organic brain syndrome, presence of severe
mental disorder and patients who are either deaf or mute
were excluded. The Malay version of Geriatric Depression
Scale (M-GDS-14) was used to assess the depressive
symptoms. The data was analysed using descriptive
statistic and multiple logistic regression.
Results: A total of 511 patients participated in the study. The
mean age of the respondents is 64.5 (Standard Deviation 7.0)
years old. There were slightly more males (53.8%). Majority
were Malay (63.0%), married (76.9%) and has a household
income of less than RM1000 (67.5%). The prevalence of
depression was 32.1%. The number of elderly people living
with their children (Adjusted Odds Ratio, aOR0.20, 95%CI:
0.07, 0.55), elderly living with spouse, children, in law and
grandchildren (aOR2.95, 95%CI: 1.18, 7.37), diabetic
complication (aOR4.68, 95%CI: 2.63, 8.35) and HbA1c
(aOR1.23, 95%CI: 1.09, 1.39) are significantly associated with
depression.
Conclusion: The level of depression was found to be high.
Factors contributing to the significantly high level of
depression are found to be associated with living
arrangements, diabetic complication and HbA1c were
significantly associated with depression.
9.Demographics of healthcare professionals’ knowledge and attitude toward deceased organ donation: Survey of critical care areas in a tertiary hospital
James William Foong ; Ong Jea Sheng ; Oo Wei Loon ; Mohammad Moshaddeque Hossain ; Nirmala Devi Baskaran ; Hasdy Haron ; Manoj Valappil ; Raghu Varadarajan
The Medical Journal of Malaysia 2019;74(2):109-115
Introduction: Organ donation rate in Malaysia is amongst
the lowest in the World. Healthcare professionals (HCPs)
working in critical care areas play an important role in the
deceased organ donation (DOD) process. This study seeks
to identify the demographics of HCPs working in the critical
care areas and their knowledge and attitudes toward the
DOD process.
Method: A cross-sectional survey on the demographics,
knowledge and attitudes of the doctors and nurses working
in critical care areas was undertaken by the random
sampling method, using a validated, structured
questionnaire. HCP’s knowledge and attitudes towards brain
death (BD), DOD, organ transplantation (OT), and
possession of organ donor card were compared against
their demographics.
Results: Four hundred and twelve (72.9%) out of the total
565 HCPs in critical care areas responded of whom 163
(39.6%) were doctors and 249 (60.4%) were nurses. After
adjusting for other factors, department of work and
profession were highly correlated with the overall
knowledge score (p<0.001 and p=0.003 respectively) and
knowledge about BD (p<0.001 and p=0.013 respectively).
HCPs from the neurosurgical intensive care unit (p<0.001)
and doctors (p<0.001) had higher mean knowledge scores
compared to their counterparts. Profession was most
significantly correlated with having a positive attitude
towards BD (p<0.001) and OT (p<0.001).
Conclusion: Department, profession and ethnicity were the
demographic characteristics that correlated with knowledge
and attitudes of HCPs on organ donation. Efforts to improve
DOD rates in Malaysia should include targeted interventions
to address the knowledge and attitudes of HCPs working in
critical care areas.
10.Evaluation of door to operation theatre time following activation of trauma team
Nik Azlan Nik Muhamad ; Ong Sheue Fen
The Medical Journal of Malaysia 2019;74(2):116-120
Introduction: This study evaluates factors that influence
door to operation theatre (OT) time in a tertiary referral
centre following activation of trauma team. Specific factors
observed in this study were association of the injury
severity score (ISS), activation of trauma team and the
number of referred specialty to door to operation theatre
time.
Methods: Retrospective chart review that evaluates all
trauma patients which required immediate operative
intervention from January 2011 to December 2015. Trauma
patients were selected from the resuscitation log book and
data were collected by chart review of selected patients.
Results: Only 5 out of 279 patients (1.8%) achieved optimal
door to OT time. (<60 minutes) Mean door to OT time was
299.27 minutes (95% CI: 280.52, 318.52). Trauma team
activation has shown significant improvement in door to OT
time (p=0.047). Time of multiple team referrals (p=0.023) and
time of operative decision (p<0.001) both had significant
impact on door to OT time. Other factors included were
demographics, ISS score, Glasgow Coma Scale (GCS),
mechanism of injury and systolic blood pressure on arrival
all which showed no significance.