1.Erratum: Patients with Acute Respiratory Distress Syndrome Caused by Scrub Typhus: Clinical Experiences of Eight Patients.
Sun Young KIM ; Hang Jea JANG ; Hyunkuk KIM ; Kyunghwa SHIN ; Mi Hyun KIM ; Kwangha LEE ; Ki Uk KIM ; Hye Kyung PARK ; Min Ki LEE
Korean Journal of Critical Care Medicine 2014;29(4):348-348
The title of page 189 should be corrected.
2.Lobar Bronchial Rupture with Persistent Atelectasis after Blunt Trauma.
Jun Hyun KIM ; Kyung Woo KIM ; Chu Sung CHO ; Sang Il LEE ; Ji Yeon KIM ; Kyung Tae KIM ; Won Joo CHOE ; Jang Su PARK ; Jung Won KIM
Korean Journal of Critical Care Medicine 2014;29(4):344-347
Rupture limited to the lobar bronchus from blunt trauma is especially rare, and the symptoms are light so diagnosis is difficult. In a patient who visited the hospital complaining of shortness of breath after falling down, atelectasis continued in the chest x-ray. Four days after visiting the hospital, a left upper lobar bronchial rupture was diagnosed through a bronchoscopy and 3 dimensional chest computerized tomography. When diagnosis is delayed in the case of a rupture limited to the lobar bronchus, bronchial obstruction can occur from the formation of granulation tissue, so regular monitoring is important. Therefore, when atelectasis continues after blunt trauma, it is important to differentially diagnose a lobar bronchial rupture through tests such as bronchoscopy.
Bronchi
;
Bronchoscopy
;
Diagnosis
;
Dyspnea
;
Granulation Tissue
;
Humans
;
Lung Injury
;
Pulmonary Atelectasis*
;
Rupture*
;
Thorax
3.Methemoglobinemia Caused by an Inert Ingredient after Intentional Ingestion of Pesticide.
Ru Bi JEONG ; Chang Hwan SOHN ; Dong Woo SEO ; Won Young KIM ; Seung Mok RYOO ; Bum Jin OH ; Kyoung Soo LIM
Korean Journal of Critical Care Medicine 2014;29(4):341-343
We report two cases of toxic methemoglobinemia caused by an inert ingredient in pesticide product after intentional ingestion of pesticide. First, 51-year-old male visited to the emergency department (ED) after the ingestion of pesticide in a suicide attempt. Initial methemoglobin (MetHb) level was 25.6%. We did not know the cause of methemoglobinemia at that time. Second, 56-year-old female visited to the ED after the ingestion of the same pesticide in a suicide attempt. MetHb level after 30 minutes was 16.1%. The patients were treated with methylene blue. We contacted to the Korean Rural Development Administration and estimated that magnesium nitrate was more likely to cause methemoglobinemia. This report highlights the importance of considering the possibility of methemoglobinemia caused by inert ingredient in pesticide and early antidotal therapy.
Eating*
;
Emergency Service, Hospital
;
Female
;
Humans
;
Magnesium
;
Male
;
Methemoglobin
;
Methemoglobinemia*
;
Methylene Blue
;
Middle Aged
;
Pesticides
;
Social Planning
;
Suicide
4.Kawasaki Disease with Acute Respiratory Distress Syndrome after Intravenous Immunoglobulin Infusion.
Yu Hyeon CHOI ; Bong Jin LEE ; June Dong PARK ; Seung Hyo KIM
Korean Journal of Critical Care Medicine 2014;29(4):336-340
Kawasaki disease (KD) is an acute systemic vasculitis of unknown etiology. We report a case of KD with acute respiratory distress syndrome (ARDS) after intravenous immunoglobulin (IVIG) infusion. Lung manifestations associated with KD have previously been reported in the literature. Although IVIG infusion is an effective therapy for acute KD, there are some reported complications related to IVIG infusion: hypotension, aseptic meningitis, acute renal failure, hemolytic anemia, etc. The case of KD reported here was treated with IVIG and aspirin. A few days after recovery from KD, the patient developed fever and maculopapular rash. A diagnosis of relapse KD was made and retreated with IVIG infusion. However, the patient developed ARDS four days after the second IVIG infusion. The patient recovered from ARDS after nine days of ICU care, which included high frequency oscillation ventilation with inhaled nitric oxide, steroid treatment and other supportive care.
Acute Kidney Injury
;
Anemia, Hemolytic
;
Aspirin
;
Diagnosis
;
Exanthema
;
Fever
;
High-Frequency Ventilation
;
Humans
;
Hypotension
;
Immunoglobulins*
;
Immunoglobulins, Intravenous
;
Lung
;
Meningitis, Aseptic
;
Mucocutaneous Lymph Node Syndrome*
;
Nitric Oxide
;
Recurrence
;
Respiratory Distress Syndrome, Adult*
;
Systemic Vasculitis
5.Cardiac Arrest due to Recurrent Ventricular Fibrillation Triggered by Unifocal Ventricular Premature Complexes in a Silent Myocardial Infarction.
Dong Hyun LEE ; Seul LEE ; Hyo Jin JUNG ; Soo Jin KIM ; Jeong Min SEO ; Jae Hyuk CHOI ; Jong Sung PARK
Korean Journal of Critical Care Medicine 2014;29(4):331-335
A 51-year-old male patient was referred for a sudden out-of-hospital cardiac arrest. Upon arrival, he was conscious and had no chest pain complaints. There was no abnormality in initial electrocardiographic and echocardiographic examinations. However, episodes of recurrent ventricular fibrillation (VF) were documented on rhythm monitoring. Each VF episode was triggered by an isolated monomorphic ventricular premature complex (VPC). Suspecting idiopathic VF, emergency radiofrequency catheter ablation was planned for the VPCs. However, when coronary angiography was performed to exclude silent ischemia, the results showed a total occlusion of the right coronary artery posterolateral branch, which is thought to supply the left ventricular inferior and septal wall. After successful reperfusion, VF episodes and the triggering VPCs disappeared. We are documenting this case to emphasize the potential for silent myocardial infarction to cause out-of-hospital sudden cardiac arrest even in a patient without any symptom or sign of acute coronary syndrome.
Acute Coronary Syndrome
;
Catheter Ablation
;
Chest Pain
;
Coronary Angiography
;
Coronary Vessels
;
Death, Sudden, Cardiac
;
Echocardiography
;
Electrocardiography
;
Emergencies
;
Heart Arrest*
;
Humans
;
Ischemia
;
Male
;
Middle Aged
;
Myocardial Infarction*
;
Out-of-Hospital Cardiac Arrest
;
Reperfusion
;
Ventricular Fibrillation*
;
Ventricular Premature Complexes*
6.Green Urine after Propofol Infusion in the Intensive Care Unit.
Min Jeong LEE ; Hyun Jeong LEE ; Jeong Min KIM ; Shin Ok KOH ; Eun Ho KIM ; Sungwon NA
Korean Journal of Critical Care Medicine 2014;29(4):328-330
Urine discoloration occurs in the intensive care unit (ICU) due to many causes such as medications, metabolic disorders, and infections. Propofol is advocated as one of the first line sedatives in the ICU, but it is not well known to the intensivists that propofol can induce urine color change. We experienced two cases of green urine after propofol infusion. Propofol should be warranted as the cause of urine discoloration during ICU stay.
Hypnotics and Sedatives
;
Intensive Care Units*
;
Propofol*
7.Traumatic Liver Injury: Factors Associated with Mortality.
Youn Suk CHAI ; Jae Kwang LEE ; Seok Jin HEO ; Yeong Ki LEE ; Yong Woo LEE ; Young Hwa JO ; Seong Soo PARK ; Hyun Jin KIM ; In Gu KANG
Korean Journal of Critical Care Medicine 2014;29(4):320-327
BACKGROUND: We postulate that a delay in the implementation of hepatic arterial embolization for traumatic liver injury patients will negatively affect patient prognosis. Our work also seeks to identify factors related to the mortality rate among traumatic liver injury patients. METHODS: From January 2008 to April 2014, patients who had been admitted to the emergency room, were subsequently diagnosed with traumatic liver injury, and later underwent hepatic arterial embolization were included in this retrospective study. RESULTS: Of the 149 patients that underwent hepatic arterial embolization, 86 had the procedure due to traumatic liver injury. Excluding the 3 patients that were admitted to the hospital before procedure, the remaining 83 patients were used as subjects for the study. The average time between emergency room arrival and incidence of procedure was 164 min for the survival group and 132 min for the non-survival group; this was not statistically significant (p = 0.170). The average time to intervention was 182 min for the hemodynamically stable group, and 149 min for the hemodynamically unstable group, the latter having a significantly shorter wait time (p = 0.047). Of the factors related to the mortality rate, the odds ratio of the Glasgow Coma Score (GCS) was 18.48 (p < 0.001), and that of albumin level was 0.368 (p = 0.006). CONCLUSIONS: In analyzing the correlation between mortality rate and the time from patient admission to arrival for hepatic arterial embolization, there was no statistical significance observed. Of the factors related to the mortality rate, GCS and albumin level may be used as prognostic factors in traumatic liver injury.
Coma
;
Embolization, Therapeutic
;
Emergency Service, Hospital
;
Humans
;
Incidence
;
Liver*
;
Mortality*
;
Odds Ratio
;
Patient Admission
;
Prognosis
;
Retrospective Studies
;
Time Factors
8.Change in Red Cell Distribution Width as Predictor of Death and Neurologic Outcome in Patients Treated with Therapeutic Hypothermia after Out-of-Hospital Cardiac Arrest.
Seongtak KIM ; Jinseong CHO ; Yongsu LIM ; Jinjoo KIM ; Hyukjun YANG ; Gun LEE
Korean Journal of Critical Care Medicine 2014;29(4):313-319
BACKGROUND: The prognostic significance of change in red cell distribution width (RDW) during hospital stays in patients treated with therapeutic hypothermia (TH) after out-of-hospital cardiac arrest (OHCA) was investigated. METHODS: Patients treated with TH after OHCA between January 2009 and August 2013 were reviewed. Patients with return of spontaneous circulation (ROSC) were assessed according to Utstein Style. Hematologic variables including RDW, hematocrit, white blood cell count, and platelets were also obtained. RDW changes during the 72 hours after ROSC were categorized into five groups as follows: Group 1 (-0.8-0.1%), Group 2 (0.2-0.3%), Group 3 (0.4-0.5%), Group 4 (0.6-0.8%), and Group 5 (>0.8%). RESULTS: A total of 218 patients were enrolled in the study. RDW changes during the 72 hours after ROSC in Group 4 (HR 3.56, 95% CI 1.25-10.20) and Group 5 (HR 5.07, 95% CI 1.73-14.89) were associated with a statistically significant difference in one-month mortality. RDW changes were associated with statistically significant differences in neurologic outcome at 6 months after ROSC (Group 3 [HR 2.45, 95% CI 1.17-5.14], Group 4 [HR 2.79, 95% CI 1.33-5.84], Group 5 [HR 3.50, 95% CI 1.35-7.41]). Other significant variables were location of arrest, cause of arrest, serum albumin, and advanced cardiac life support time. CONCLUSIONS: RDW change during the 72 hours after ROSC is a predictor of mortality and neurologic outcome in patients treated with TH after OHCA.
Advanced Cardiac Life Support
;
Erythrocyte Indices*
;
Hematocrit
;
Humans
;
Hypothermia*
;
Length of Stay
;
Leukocyte Count
;
Mortality
;
Out-of-Hospital Cardiac Arrest*
;
Prognosis
;
Serum Albumin
9.Prognostic Value and Optimal Sampling Time of S-100B Protein for Outcome Prediction in Cardiac Arrest Patients Treated with Therapeutic Hypothermia.
Hyung Seok KIM ; Ho Sung JUNG ; Yong Su LIM ; Jae Hyug WOO ; Jae Ho JANG ; Jee Yong JANG ; Hyuk Jun YANG
Korean Journal of Critical Care Medicine 2014;29(4):304-312
BACKGROUND: The aim of this study was to determine the prognostic value and optimal sampling time of serum S-100B protein for the prediction of poor neurological outcomes in post-cardiac arrest (CA) patients treated with therapeutic hypothermia (TH). METHODS: We prospectively measured serum S100 calcium binding protein beta subunit (S-100B protein) levels 12 times (0-96 hours) after the return of spontaneous circulation (ROSC). The patients were classified into two groups based on cerebral performance category (CPC): the good neurological outcome group (CPC 1-2 at 6 months) and the poor neurological outcome group (CPC 3-5). We compared serial changes and serum S-100B protein levels at each time point between the two groups and performed receiver operating characteristic curve analysis for the prediction of poor neurological outcomes. RESULTS: A total of 40 patients were enrolled in the study. S-100B protein levels peaked at ROSC (0 hour), decreased rapidly to 6 hours and maintained a similar level thereafter. Serum S-100B protein levels in the poor CPC group (n = 22) were significantly higher than in the good CPC group (n = 18) at all time points after ROSC except at 4 hours. The time points with highest area under curve were 24 (0.829) and 36 (0.837) hours. The cut-off value, the sensitivity (24/36 hours) and specificity (24/36 hours) for the prediction of poor CPC at 24 and 48 hours were 0.221/0.249 ug/L, 75/65% and 82.4/94.1%, respectively. CONCLUSIONS: Serum S-100B protein was an early and useful marker for the prediction of poor neurological outcomes in post-CA patients treated with TH and the optimal sampling times were 24 and 36 hours after ROSC.
Area Under Curve
;
Heart Arrest*
;
Humans
;
Hypothermia*
;
Prospective Studies
;
ROC Curve
;
S100 Calcium Binding Protein beta Subunit*
;
Sensitivity and Specificity
10.Effectiveness of Bradycardia as a Single Parameter in the Pediatric Acute Response System.
Yu Hyeon CHOI ; Hyeon Seung LEE ; Bong Jin LEE ; Dong In SUH ; June Dong PARK
Korean Journal of Critical Care Medicine 2014;29(4):297-303
BACKGROUND: Various tools for the acute response system (ARS) predict and prevent acute deterioration in pediatric patients. However, detailed criteria have not been clarified. Thus we evaluated the effectiveness of bradycardia as a single parameter in pediatric ARS. METHODS: This retrospective study included patients who had visited a tertiary care children's hospital from January 2012 to June 2013, in whom ARS was activated because of bradycardia. Patient's medical records were reviewed for clinical characteristics, cardiologic evaluations, and reversible causes that affect heart rate. RESULTS: Of 271 cases, 261 (96%) had ARS activation by bradycardia alone with favorable outcomes. Evaluations and interventions were performed in 165 (64.5%) and 13 cases (6.6%) respectively. All patients in whom ARS was activated owing to bradycardia and another criteria underwent evaluation, unlike those with bradycardia alone (100.0% vs. 63.2%, p = 0.016). Electrocardiograms were evaluated in 233 (86%) cases: arrhythmias were due to borderline QT prolongation and atrioventricular block (1st and 2nd-degree) in 25 cases (9.2%). Bradycardia-related causes were reversible in 202 patients (74.5%). Specific causes were different in departments at admission. Patients admitted to the hemato-oncology department required ARS activation during the night (69.3%, p = 0.03), those to the endocrinology department required ARS activation because of medication (72.4%, p < 0.001), and those to the gastroenterology department had low body mass indexes (32%, p = 0.01). CONCLUSIONS: Using bradycardia alone in pediatric ARS is not useful, because of its low specificity and poor predictive ability for deterioration. However, bradycardia can be applied to ARS concurrently with other parameters.
Arrhythmias, Cardiac
;
Atrioventricular Block
;
Body Mass Index
;
Bradycardia*
;
Electrocardiography
;
Endocrinology
;
Gastroenterology
;
Heart Arrest
;
Heart Rate
;
Hospital Rapid Response Team
;
Humans
;
Medical Records
;
Pediatrics
;
Retrospective Studies
;
Sensitivity and Specificity
;
Tertiary Healthcare