1.The hormonal threshold area of menstruation
Journal of Medical Research 2000;12(2):44-49
Through studies on the hormonal threshold area of menstruation had shown that the hormonal threshold area of menstruation is not a right line but an area consisted of two limits, superior and inferior ones. Menstrual bleeding occurred only when the curve of hormonal effect on development of the endometrium is situated in this area of two limits. Above or under that threshold area the curve of hormonal effect on development does not cause endometrial hemorrhage. The author also showed that the superior limit has a mean value 57.65±43.36 pmol/L and the inferior one is at 29.27±19.43 pmol/L of estradiol. Basing on the above statement the author suggested that the menstruation may be defined as occurred when the curve of hormonal effect on endometrial development situates in a threshold area of menstrual bleeding and not when the sexual steroids go down under a certain threshold as earlier
Hormones
;
Menstruation
2.Nutritional therapy in chronic renal failure
Journal of Medical Research 1998;7(3):47-49
The selective low protein dietary in treatment of chronic renal failure aims at objectives in cluding reduction of symptom of hyperuremia and protection of function of rest normal kidney. However, the limitation of daily protein need will lead to lack of essential aminoacide. Use of ketoacid corresponding with aminoacid reduces the nitrogen supply, prevents the bad progress of chronic renal failure and limits the excessive filtration of glomerular, hyperphosphatemia and secondary increased para- thyroid function.
Kidney Failure, Chronic
;
diet therapy
3.The fourth bronchial pouch fistula and analysis of 20 cases
Journal of Medical Research 2000;13(3):3-8
The fourth bronchial pouch fistulae is the lesion of the fourth bronchial-pharyngeal duct in development of the embryo. 20 cases of this disease were diagnosed, operated and followed-up in the institute of ENT, from 1995 to 1997. 11 females and 9 males were affected; It manifested itself by recurrent episodes neck abscess, especially on the left side (95%). 13 fistulous tracts were found on operation with 86% of retrocartilaginous course.
Bronchial Fistula
;
Pouchitis
4.The role of transbronchial fine needle aspiration in the diagnosis of submucosal bronchogenic carcinoma
Journal of Medical Research 2002;18(2):7-12
Transbronchial needle aspiration in the diagnosis of submucosal bronchogenic carcinoma. Although exophytic endobronchial lesions can readily be diagnosed by forceps biopsy through the rigid bronchoscope. The lesion of submucosal or peribronchial by forceps biopsy difficult to diagnose by biopsy. The utility of transbronchial fine needle aspiration through rigid bronchoscope was made in 98 patients presenting with endoscopic abnormalities suggestive of submucosal bronchigenic carcinoma of respiratory department of Bachmai hospital from 3/1991 to 7/1996. Forceps biopsy was positive in 48 patients (58.77%). Transbronchial needle aspiration was positive in 88 patients (88.79%) and detected 6 cases additional carcinomas (who were treated by anti-tuberculosis of the lung). We concluded that TBNA significantly increases the yield, more effective than forceps biopsy alone in the detection of the infiltration of submucosal bronchogenic carcinoma.
suction
;
neoplasms
5.Immunohistochemical study of primary extranodal malignant non-Hodgkin's lymphoma
Journal of Medical Research 2000;13(3):20-23
Between 1996 and 1998, 31 cases of primary extranodal malignant non-Hodgkin's lymphoma were studied immunohistochemically. Immunohistochemical study showed that the majority of the cases were of B-cell type: 19 cases (73.07%) and only 3 cases (11.53%) were of the T-cell type. According to the Working Formulation system, the most common histologic type was diffuse, large cell type (61.29%). The histologic grade was moderate grade: 23 cases (74.19%), high grades: 5 cases (16.13%).
Immunohistochemistry
;
Lymphoma, Non-Hodgkin
6.Mobilization with granulocyte \ufffd?colony stimulating factor (G-CSF) and collection peripheral blood CD34 cells from healthy volunteer for allograft
Tung Quang Nguyen ; Tri Anh Nguyen ; Phan Trung Do
Journal of Medical Research 2007;47(1):13-19
Background: Peripheral blood stem cells are today the mains source of cells for transplantation. The number of CD34 in peripheral blood of adult healthy volunteers is very low, so we have to mobilize. Objectives: To apply a protocol to collect CD4 cells in peripheral blood of normal donors mobilized by using G-CSF. Subjects and method: G-CSF (Leukokin) at a dose 10 mcg/kg/day was injected subcutaneously in 5 consecutive days for mobilization CD34 from 5 healthy donors. Count the number of CD34 everyday and collect CD34 cells in 5th \ufffd?6th day by automated blood cell separator (COBE-Spectra), observed clinical and hematilogy, biochemistry symtoms spontaneously. Results: The number of CD34 harvested is 215,5 \ufffd?570,2 x 106 CD34/donor. Almost other of parameters of hematology and biochemistry of donors were normal after one week from the last separation. Conclusion: Mobilization with G-CSF and aphaeresis of periphral blood stem cell from normal donors is feasibility and safety. The number of CD34 can be to allograft for an adult patient.
Hematopoietic Stem Cells
;
Granulocyte Colony-Stimulating Factor
;
7.The preliminary report of occult HBV infection in Vietnamese
Truong Xuan Bui ; Bang Van Nguyen ; Phuong Minh Tran ; Trach Khanh Nguyen ; Quy Tran ; Yoshihiko Yano ; Yasushi Seo ; Yoshitake Hayashi
Journal of Medical Research 2007;47(1):28-32
Background: Vietnam is located in the endemic region of hepatitis B virus (HBV) infection, but no data of occult HBV infection was reported at present. Objectives: To investigate the prevalence of occult HBV infection in different ethnics of people and generations. Subjects and method: 80 voluteers with HbsAg negative from five different ethnics: Kinh, Tay, Mong, Giay and Dao in a Chino \ufffd?Vietnamses border province (Lao Cai) were enrolled in the study. After HBV-DNA was extracted, nested PCR of S gene and of Core-promoter/Pre-core region were used to detect HBV-DNA. Specifying nucleotide sequence was confirmed by direct sequencing. Results:The prevalence of occult HBV infection in population study was very high 73/80 (91,3%) by nested PCR of Core-promoter/Pre-core, significantly more sensitive than nested PCR of S gene (26,3%) (p<0,0001). The prevalence of occult HBV infection was notdifferent between ethnics of people or between children, adults. Conclusion: Occult HBV infection in Vietnamese is very common; however, nationwide further studies should be carried out to confirm this preliminary results and evaluate the impact of occult HBV infection in Vietnam.
Hepatitis B virus
;
Hepatitis B Surface Antigens
;
8.Intubation condition and side effects of different doses of succinylcholine
Thu Thi Minh Nguyen ; Tu Huu Nguyen
Journal of Medical Research 2007;47(1):44-49
Background: Succinylcholine is drug muscle relaxant the only depolarizing current can also be used in clinical. Objectives: The current study assessed the intubation condition and side effects of different doses of succinylcholine. Subjects and method: In a randomized, double blind trial, 90 patients were divided into 3 groups. 1, 1.5 or 2 mg/kg succinylcholine was added with Fentanyl and Thiopental for induction in group I, II and III, respectively. A rapid induction and postoperative myalgia were evaluated. Results: Fasciculation time as well as myalgia increased significantly by the doses. Intubation conditions were better in group II and III. Increase of kalemia was seen in all groups, but most significantly in group III (3,7 \xb1 0,3 vs 3,3 \xb1 0,2, p<0,05). Conclusion: 1, 1.5 or 2 mg/kg succinylcholine equally provided acceptable intubation condition. Succinylcholine 2 mg/kg induced more fasciculation, myalgia and increase of kalemia.
Succinylcholine/ adverse effects
;
Intubation
;
9.Treatment of Hodgkin\u2019s disease with ABVD followed by low-dose involved field of radiotherapy: analysis of efficacy
Mai Tuyet Nguyen ; Duc Ba Nguyen
Journal of Medical Research 2007;47(1):60-64
Background: Treatment of Hodgkin\u2019s disease with ABVD followed by low-dose involved field of radiotherapy is currently considered the standard of care. Objectives: This study was evaluated the efficacy and some pronogstic factors. Subjects and method: 103 consecutive patients with newly diagnosed HD\ufffd?disease treated with combination CT and RT at K-hospital between 10/2001 \ufffd?3/2005 were eligible. The end points of the study were complete response (CR), relapse-free survival (RFS), overall survival (OS). Tests were used for analysis: chi-square test, Kaplan-Meier method... Results: 103 patients (100%) achieved a CR. The RFS and OS rate at 5 years were 64,6% and 91,7%. Pronogstic factors are sex, anemia, B symtom, liver lesion. Conclusion: Treatment plan has brought the most effective so far. Liver damage is a bad influence markedly the survival time.
Hodgkin Disease/ radiotherapy
;
10.Evaluation of vitrectomy for severe penetrating eye injury in children
Journal of Medical Research 2007;47(1):73-77
Background: Severe penetrating eye injury is a common emergency in ophthalmology. Objectives: The evaluation results and complications following vitrectomy in severe penetrating injury in children. Subjects and method: This study included 136 eyes with penetrating eye injury, who were treated at the Trauma department of National Institute of Ophthalmology, Hanoi \ufffd?Vietnam from 1999-2000. Vitrectomy was performed through the limbal and pars plana in 135 patients, 105 boys and 30 girls. Results: Remove intraocular foreign body: 11%, procedure for retinal detachments: 14%. The common functional success (visual acuity of 5/2000 or better) rate was 55,1%. Functional success: absent retinal detachment: 60,7%; present: 21,1%. Anatomic success rate was 66,2%. 4 eyes (2,9%) were eviscerated. Complications of the surgery were: iridocyclite, edema of the cornea, hemorrhage, hyphema. Conclusion:Vitrectomy techniques showed its good effect in treating penetrating eye injury in children. Presence retinal damage and endophthalmitis have significant effect on the final visual outcomes.
Eye Injuries
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Penetrating/ surgery
;
Vitrectomy
;
Child
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