1.Response: Characterization of Patients with Type 2 Diabetes according to Body Mass Index: Korea National Health and Nutrition Examination Survey from 2007 to 2011 (Endocrinol Metab 2015;30:514-21, Dong-Hwa Lee et al.).
Endocrinology and Metabolism 2016;31(2):347-348
No abstract available.
Body Mass Index*
;
Humans
;
Korea*
;
Nutrition Surveys*
2.Letter: Characterization of Patients with Type 2 Diabetes according to Body Mass Index: Korea National Health and Nutrition Examination Survey from 2007 to 2011 (Endocrinol Metab 2015;30:514-21, Dong-Hwa Lee et al.).
Endocrinology and Metabolism 2016;31(2):345-346
No abstract available.
Body Mass Index*
;
Humans
;
Korea*
;
Nutrition Surveys*
3.18F-FDG PET/CT-Guided Clinical Management of the Rare Aggressive "Columnar-Cell" Variant of Papillary Thyroid Cancer.
Manuela VADRUCCI ; Giovanni SERIO ; Alberto BAROLI
Endocrinology and Metabolism 2016;31(2):343-344
No abstract available.
Fluorodeoxyglucose F18*
;
Thyroid Gland*
;
Thyroid Neoplasms*
4.Response: The Association between Serum Endogenous Secretory Receptor for Advanced Glycation End Products and Vertebral Fractures in Type 2 Diabetes (Endocrinol Metab 2012;27:289-94, Cheol Ho Lee et al.).
Cheol Ho LEE ; Min Kyung LEE ; Hyun Jeong HAN ; Tae Ho KIM ; Jae Hyuk LEE ; Se Hwa KIM
Endocrinology and Metabolism 2013;28(1):78-79
No abstract available.
Glycosylation End Products, Advanced
5.Letter: The Association between Serum Endogenous Secretory Receptor for Advanced Glycation End Products and Vertebral Fractures in Type 2 Diabetes (Endocrinol Metab 2012;27:289-94, Cheol Ho Lee et al.).
Endocrinology and Metabolism 2013;28(1):76-77
No abstract available.
Glycosylation End Products, Advanced
6.Olanzapine-Induced Diabetic Ketoacidosis and Neuroleptic Malignant Syndrome with Rhabdomyolysis: A Case Report.
Young Kyoung SA ; Hyeon YANG ; Hee Kyoung JUNG ; Jang Won SON ; Seong Su LEE ; Seong Rae KIM ; Bong Yeon CHA ; Ho Young SON ; Chi Un PAE ; Soon Jib YOO
Endocrinology and Metabolism 2013;28(1):70-75
Atypical antipsychotics have replaced conventional antipsychotics in the treatment of schizophrenia because they have less of a propensity to cause undesirable neurologic adverse events including extrapyramidal symptoms, tardive dyskinesia, and neuroleptic malignant syndrome (NMS). However, atypical antipsychotics have been known to result in various metabolic complications such as impaired glucose tolerance, diabetes and even diabetic ketoacidosis (DKA). In addition, a number of NMS cases have been reported in patients treated with atypical antipsychotics, although the absolute incidence of neurologic side effects is currently significantly low. Here, we report a patient who simultaneously developed DKA, acute renal failure and NMS with rhabdomyolysis after olanzapine treatment. Olanzapine-induced metabolic complications and NMS were dramatically improved with cessation of the olanzapine treatment and initiation of supportive management including fluid therapy, hemodialysis, and intensive glycemic control using insulin. At short-term follow-up, insulin secretion was markedly recovered as evidenced by a restoration of serum C-peptide level, and the patient no longer required any hypoglycemic medications. Despite the dramatic increase in the use of atypical antipsychotics treatment, individualized treatments along with careful monitoring may be prudent for high risk or vulnerable patients in order to avoid the development of metabolic side effects.
Acute Kidney Injury
;
Antipsychotic Agents
;
Benzodiazepines
;
C-Peptide
;
Diabetic Ketoacidosis
;
Fluid Therapy
;
Follow-Up Studies
;
Glucose
;
Humans
;
Incidence
;
Insulin
;
Movement Disorders
;
Neuroleptic Malignant Syndrome
;
Renal Dialysis
;
Rhabdomyolysis
;
Schizophrenia
7.Steroid Responsive Xanthomatous Hypophysitis Associated with Autoimmune Thyroiditis: A Case Report.
Ji Young JOUNG ; Hyemin JEONG ; Yoon Young CHO ; Kyoungmin HUH ; Yeon Lim SUH ; Kwang Won KIM ; Ji Cheol BAE
Endocrinology and Metabolism 2013;28(1):65-69
We report the case of a 36-year-old woman who presented with headache, fever, and amenorrhea. Laboratory analysis revealed hypopituitarism and autoimmune thyroiditis, while a cerebrospinal fluid study suggested concurrent aseptic meningitis. A magnetic resonance image (MRI) scan revealed a 1.0x0.9 cm cystic mass enlarging the sella turcica. Surgical resection via an endoscopic transsphenoidal route was performed. The histological finding of the excised tissue revealed foamy histiocytes with vacuolated cytoplasm, supporting the diagnosis of xanthomatous hypophysitis. Although a residual soft lesion was observed on the MRI image postoperatively, the patient's headache and fever improved. Ten months after surgery, the patient complained of visual impairment and headache, and the residual mass had enlarged into the suprasellar area. High dose (500 mg intravenous) methylprednisolone was administered for 3 days. During the methylprednisolone pulse therapy, the patient's visual acuity and headache improved. A follow-up MRI taken after methylprednisolone therapy showed a marked mass reduction. Our case supports an autoimmune pathophysiology for xanthomatous hypophysitis and suggests that high dose glucocorticoid therapy as a treatment option.
Amenorrhea
;
Cytoplasm
;
Female
;
Fever
;
Follow-Up Studies
;
Glucocorticoids
;
Headache
;
Histiocytes
;
Humans
;
Hypopituitarism
;
Magnetic Resonance Spectroscopy
;
Meningitis, Aseptic
;
Methylprednisolone
;
Sella Turcica
;
Thyroiditis, Autoimmune
;
Vision Disorders
;
Visual Acuity
8.Anaplastic Thyroid Carcinoma Following Radioactive Iodine Therapy for Graves' Disease.
Sun Hwa KIM ; Hee Young KIM ; Kwang Yoon JUNG ; Dong Seop CHOI ; Sin Gon KIM
Endocrinology and Metabolism 2013;28(1):61-64
Radioactive iodine (RAI) therapy has been used as a treatment option for Graves' disease, and it has been widely accepted to be safe. On the other hand, some evidence suggests that RAI therapy is possibly associated with a small increased risk of thyroid cancer. Herein, we report a rare case of anaplastic thyroid carcinoma (ATC) associated with Graves' disease, following RAI treatment. A 42-year-old woman had been diagnosed with Graves' disease and although she was treated with an antithyroid drug, she remained in a hyperthyroid state, which led to two RAI treatments. More than 10 years later, the patient revisited our clinic due to hoarseness, dysphagia, and dyspnea, which had lasted for 2 months. Neck computed tomography suggested thyroid carcinoma and a lymph node biopsy showed metastatic papillary carcinoma. The patient underwent total thyroidectomy and was finally diagnosed as having an ATC. It is not clear if the occurrence of ATC reported here was influenced by the RAI therapy or alternatively, it may only represent the delayed recognition of a rare change in the natural history of Graves' disease. Nevertheless, this report is worthwhile since it presents a very rare case of ATC that occurred eleven years after the RAI therapy for Graves' disease.
Biopsy
;
Carcinoma, Papillary
;
Deglutition Disorders
;
Dyspnea
;
Female
;
Graves Disease
;
Hand
;
Hoarseness
;
Humans
;
Iodine
;
Lymph Nodes
;
Natural History
;
Neck
;
Thyroid Gland
;
Thyroid Neoplasms
;
Thyroidectomy
9.Two Cases of Methimazole-Induced Insulin Autoimmune Syndrome in Graves' Disease.
Eun ROH ; Ye An KIM ; Eu Jeong KU ; Jae Hyun BAE ; Hye Mi KIM ; Young Min CHO ; Young Joo PARK ; Kyong Soo PARK ; Seong Yeon KIM ; Soo Heon KWAK
Endocrinology and Metabolism 2013;28(1):55-60
We report here the cases of two females with Graves' disease who developed insulin autoimmune syndrome after treatment with methimazole. The patients exhibited a sudden altered mental state after treatment with methimazole for approximately 4 weeks. Patients had hypoglycemia with serum glucose below 70 mg/dL, and laboratory findings showed both high levels of serum insulin and high titers of insulin autoantibodies. The two women had never been exposed to insulin or oral antidiabetic agents, and there was no evidence of insulinoma in imaging studies. After glucose loading, serum glucose, and total insulin levels increased abnormally. One of the patient was found to have HLA-DRB1*0406, which is known to be strongly associated with methimazole-induced insulin autoimmune syndrome. After discontinuation of methimazole, hypoglycemic events disappeared within 1 month. Insulin autoantibody titer and insulin levels decreased within 5 months and there was no further development of hypoglycemic events. We present these cases with a review of the relevant literature.
Autoantibodies
;
Female
;
Glucose
;
Graves Disease
;
HLA-DRB1 Chains
;
Humans
;
Hypoglycemia
;
Hypoglycemic Agents
;
Insulin
;
Insulinoma
;
Methimazole
10.A Case of Acute Suppurative Thyroiditis with Thyrotoxicosis in an Elderly Patient.
Bo Sang KIM ; Kil Woo NAM ; Jeong Eun KIM ; Ji Hoon PARK ; Jun Sik YOON ; Jung Hwan PARK ; Sang Mo HONG ; Chang Bum LEE ; Yong Soo PARK ; Woong Hwan CHOI ; You Hern AHN ; Dong Sun KIM
Endocrinology and Metabolism 2013;28(1):50-54
Acute suppurative thyroiditis (AST) is a rare condition, as the thyroid gland is relatively resistant to infection. Thyroid function tests are usually normal in AST. A few cases of AST associated with thyrotoxicosis have been reported in adults. We report a case of AST that was associated with thyrotoxicosis in a 70-year-old woman. We diagnosed AST with thyroid ultrasonography and fine needle aspiration of pus. The patient improved after surgical intervention and had no anatomical abnormality. Fine needle aspiration is the best method for the difficult task of differentiating malignancy and subacute thyroiditis from AST with thyrotoxicosis. Earlier diagnosis and proper treatment for AST might improve the outcome.
Adult
;
Aged
;
Biopsy, Fine-Needle
;
Female
;
Humans
;
Suppuration
;
Thyroid Function Tests
;
Thyroid Gland
;
Thyroiditis, Subacute
;
Thyroiditis, Suppurative
;
Thyrotoxicosis