The corresponding season of the ve zang-viscera is the important content of the correspondence between man and universe theory in the Inner Canon of Huangdi,and the corresponding season of the ve zang-viscera related to several modes of calendar.With the exception of the way that combine the ve zang-viscera with calendar which make use of criss and cross or divide into ve parts on 12 months of a year,the authors believe that the newly discovered ancient ten months' calendar had been showed clearly in the Inner Canon of Huangdi.The text of the Inner Canon of Huangdi that cannot be explained well in accordance with twelve months' calendar can be explained by ancient ten months' calendar,and the ancient ten months' calendar is the basis that the ve phases theory is derived from the concept of the ve seasons.

This article elucidates the deficient pathogenesis of the essence-qi-yin-yang of five zang viscera and its related questions.It is pointed that essence deficiency,qi deficiency,yin deficiency and yang deficiency of five zang viscera can explain their different diseases and syndromes,and belong to series-syndrome(类证) pathogenesis.Yin deficiency and yang deficiency of five zang viscera can not happen together with qi deficiency.However they can happen at the same time with the essence deficiency,blood deficiency and body fluid deficiency.The essence deficiency,qi deficiency,yin deficiency and yang deficiency of Kidney are very important to the deficient pathogenesis of the essence-qiyin-yang of five zang viscera.

The ancient methods of pulse-reading represented by Bian Que and Nei Jing are the initiation and formation stages of pulse examination in TCM.Allround,rich and colorful methods of meridian examination are foundation and condition of pulse examination.The development of pulse examination is a distinct course,from complicated to simple,mixed to exclusive.The purpose of this article is,from the point of view in the origin of pulse examination,to explore the relationship between meridian and the formation of pulse examination.

Symptom in TCM is named "sign" for short,including subjective symptom and objective sign,which is the objective reflection of pathological changes occurred in human body and is the basis of the formation of pattern of syndrome and treatment based on syndrome differentiation in TCM.The study of the normalization of symptom in TCM is one of the most important contents of the TCM basic theory research.This article from linguistics visual angle,through the objective analysis on symptom describing language of 21 ancient medical books before the Tang Dynasty,found that symptom language in TCM implicated logical rule under numerous and unordered appearance,that was presenting multiple grammar forms,basically fixed presentation mode and important effect of double words and metaphor in the symptom presentation etc.Among the total,three grammar forms are easy to normalize,and they constitute the most foundational nomenclatures of symptom in TCM.Meanwhile,the normalization of symptom in TCM is a complicated project,only with omnibearing and multiple visual angles,can it gain plentiful and substantial achievement.

Objective: To optimize the preparation procedure of coptis in Shutangluo Capsule.Methods: The orthogonal design(L9(34)) was carried out for the optimum extraction conditions of coptis in Shutangluo Capsule.By determining berberine hydrochloride with HPLC method,the mobile phase of HPLC was CH3CN-0.1%H3PO4-CH3(CH2)10CH2OSO2Na(40:60:0.12g).Results: The best extraction process was as follows: reflux with 6 times of 70% alcohol for two times,every time for 1.5hr.Conclusion: The optimum extraction technology is rational and feasible with high extraction rate of berberine hydrochloride.

Objective: To investigate the intervention of Shiquan Dabu Decoction (SQDBD) in the protein expression of VEGF. Methods: 50 C57BL/6 mice inoculated with lewis lung cancer were randomly divided into five groups and treated by different drugs. The ratio of antitumorand and antimetastatic of each group were calculated after 15 days’ treatment. The expression of VEGF was detected by SABC immunohistochemical method. Results: Low, medium and high dosages of SQDBD had the function of antitumor and antimetastusi at different extent. SQDBD could inhibit the positive expression of VEGF protein. Conclusion: Inhibition of the expression of VEGF protein is possibly one of the mechanisms of SQDBD in antitumor.

Chinese medicine has certain advantages in treating the disease of children ADHD which caused by brain dysfunction. According to the physiological characteristics of "kidney is often insufficient" in children, and the close relations among kidney, marrow, essence and brain, we put forward the pathomechanism hypothesis that growth retardation of spinal marrow caused ADHD, and thought that the def iciency of kidney essence, growth retardation of spinal marrow, and imbalance of yin and yang (yang superabundant and yin insufficient), are the keys of pathomechanism of ADHD. Accordingly, the tonifying kidney and replenishing essence treatment principle was established, and YiZhiNingShen granule was made which had been conf irmed effectively by clinical and experimental research.

Objective: To study the chemical constituents of volatile oil from flower of Dendrobium candidum Wall. ex Lind1. Methods: The chemical compositions of volatile oil of the plant which were obtained by steam distillation with hexane were analyzed by GC-MS equipped with a elastic quartz capillary column-HP-5MS5% Phenyl Methyl Siloxane (30 m? 0.25 mm ?0.25 ?m). The constituents were identifi ed by their mass spectra. The relative percentage of the oil constituents was calculated from the GC peak areas. Results: Eighty-nine kinds of chemical constituents in Dendrobium candidum Wall.ex Lind1.flower were separated; of which fifty-nine compounds representing 76.51% of the oil were characterized. Relative contents that were more than 2.0% were determined as Nonanal 9.21%, Eudesma-5,11-dien-8,12-olide 5.55%, (E)-2-Decenal 4.63%, 2,3-Dehydro- 1,8-cineole 4.39%, Pentacosane 4.03%,?-Cedrol 3.69%, Isoalantolactone 3.65%, (E)-2-Heptenal 3.60%, E,E-2,4-Decadienal 2.14%,?-Phorone 2.03%.Conclusion: This paper reports, for the first time, the composition of volatile oils of Dendrobium candidum Wall.ex Lind1.flower by GC/MS.

Objective: To provide foundation for clinical application through studying the drug action and mechanism of action of Lingdantongfengkang Capsule on anti-gout effects. Methods: Lingdantongfengkang Capsule was taken orally. The experimental methods were as follow: mouse ear swell induced by dimethylbenzene, mouse pain induced by injecting acidum aceticum in abdominal cavity, mouse hyperuricemia model induced by yeast. Results: Lingdantongfengkang Capsule could lessen mouse ear swell induced by dimethylbenzene, decreae mouse stretching frequencies induced by injecting acidum aceticum in abdominal cavity and antagonize animal serum uric acid,liveness of xanthinoxidase and urea nitrogen induced by yeast to mice.Conclusion: Lingdantongfengkang Capsule possesses the anti-gout effects.

To raise clinical curative effect through quantitative and synthesize analysis of Traditional Chinese Medicine (TCM). According to Zhongjing’s medicine usage regulation and the author’s clinical fulfillment, a generalization, contrast and synthesize analysis among the same kind medicines is carried on in the text. It put forward the conception of "First-line medicine" for the first time and carried on detailed treatise of its nature, effect, classification, application and regulation. Meanwhile, the important role and function of "First-line medicine" is conf irmed in the text, and hope it is wished to helpful to the usage of TCM in clinical practice.