2.A Study on the Distribution of NADPH-Diaphorase and Neuropeptide Y Positive Neurons in the Cerebral Cortex of Apodemus Agrarius.
Young Bum HUH ; Seung Joon HWANG ; Jung Sik JO
Korean Journal of Anatomy 1997;30(1):57-64
Apodemus agrarius has been using for experimental purpose to identifying the route of infection and pathogenesis of korean hemorrhagic fever. However, despite the increasing amount of information being published at present about the physiologic and ecologic characteristics of Apodemus, few data are availalle about the morphologic findings in the brain. The NADPH-diaphorase[NADPH-d] positive neurons, uniquely resistant to toxic insults and neurodegenerative diseases, have been colocalized with neurons in the brain and peripheral tissue containing nitric oxide synthase, which generates nitric oxide, a recently identified neuronal messenger molecule. In this study we used NADPH-d histochemistry to evaluate the distribution of neuropeptide Y-immunoreactive[NPY-IR] cells within neurons which contain nitric oxide synthase. In the cerebral cortex of Apodemus agrarius, NADPH-d positive and NPY-IR neurons were observed in all cortical layers, but they were concentrated in two bands layer II/III and V/VI extending into the subcortical white matter. Double labeling for NADPH-d and NPY showed colocalization of NPY with NADPH-d in numerous neurons of the cerebral cortex. The data obtained showed that about 74-79% of NPY-IR neurons contained NADPH-d in the neocortex and that 77-89% in the allocortex. The number of NPY-IR/NADPH-d positive neurons was about 10-13 per unit area [2,500,000 micrometer] in the neocortex and about 11-25 in the allocortex except retrosplenial cortex. In the retrosplenial cortex, the number of double labeled neurons was about 5 per unit area. NPY-IR and NADPH-d positive neurons were predominantly medium-sized with extended, multipolar or bipolar dendritic branches which belong to fusiform or stellate cell types. A moderately dense network of fine, varicose NADPH-d positive fibers was present throughout all cortical layers.
Animals
;
Brain
;
Cerebral Cortex*
;
Hemorrhagic Fever with Renal Syndrome
;
Murinae*
;
Neocortex
;
Neurodegenerative Diseases
;
Neurons*
;
Neuropeptide Y*
;
Neuropeptides*
;
Nitric Oxide
;
Nitric Oxide Synthase
3.A Study of Interleukin -8 in the Peritoneal Fluid of Patients with Endometriosis.
Han Bum LEE ; Tae Bum JUNG ; Joong Suk KIM ; Jung Bae KANG ; Hong Bae KIM ; Geun Young LEE ; Sung Won KANG
Korean Journal of Obstetrics and Gynecology 2000;43(8):1331-1335
No abstract available.
Ascitic Fluid*
;
Endometriosis*
;
Female
;
Humans
;
Interleukins*
4.Erythema Multiforme Induced by Topical Application of Viru-Merz® Ointment.
Sook Jung YUN ; Jee Bum LEE ; Seung Chul LEE ; Young Ho WON
Annals of Dermatology 2001;13(1):66-69
Viru-Merz® ointment,1% tromantadine hydrochloride, is a topical antiviral agent used for recurrent herpes simplex. There are many reported cases of contact dermatitis by tromantadine.But erythema multiforme-like eruptions in association with Viru-Merz® Ointment has not been reported. A 31-year-old woman, who applied Viru-Merz® ointment for a recurrent herpes simplex labialis, developed an allergic contact dermatitis. Erythema multiforme like eruptions with typical target feature followed around the eczematous lesions on the face, and spread progressively on the neck and trunk. A patch test revealed positive reaction to Viru-Merz® ointment.
Adult
;
Dermatitis, Allergic Contact
;
Dermatitis, Contact
;
Erythema Multiforme*
;
Erythema*
;
Female
;
Herpes Simplex
;
Humans
;
Neck
;
Patch Tests
5.Mycobacterium chelonae Skin Infection after Autologous Fat Transplantation.
Joon Bum LEE ; Jin Woong JUNG ; Young Wook RYOO ; Sung Ae KIM
Korean Journal of Dermatology 2017;55(10):710-711
No abstract available.
Mycobacterium chelonae*
;
Mycobacterium*
;
Skin*
6.A Case of Transient Acrodermatitis Enteropathica in a Full-Term Breast-Fed Infant.
Jee Youn WON ; Gi Bong JUNG ; Young Min JEON ; Jee Bum LEE ; Eun Sup SONG
Korean Journal of Dermatology 1999;37(6):790-793
We herein report a case of transient acrodermatitis enteropathica in a 3-month-old, breast-fed, full-term infant. The patient was presented with a 2-month history of diarrhea and crusted erythema- tous patches on the periorificial area. Similar lesions were seen in his siblings. His serum zinc level and the zinc level in his mother's breast milk were markedly reduced. Diarrhea and skin lesions disappeared promptly with oral zinc supplementation and did not recur when zinc was discontinued after three weeks. Our case indicates that even full-term infants, who feed excl-usively on mothers milk, run a risk of developing zinc deficiency, if the concentration of zinc in the breast milk is very low.
Acrodermatitis*
;
Diarrhea
;
Humans
;
Infant*
;
Milk
;
Milk, Human
;
Mothers
;
Siblings
;
Skin
;
Zinc
7.A study on the delayed-type hypersensitivity skin reaction using multi-test kit in abdominal operation patients.
Woo Song HA ; young Hyun CHO ; Sang Bum KIM ; Jung In JE ; Ok Jae LEE
Journal of the Korean Surgical Society 1993;44(6):788-796
No abstract available.
Humans
;
Hypersensitivity*
;
Skin*
8.Cavitary lung abscess mistaken for pneumothorax after drainage of pus.
Bum Kee HONG ; Jung Hyun CHANG ; Se Kyu KIM ; Sung Kyu KIM ; Won Young LEE
Tuberculosis and Respiratory Diseases 1993;40(4):449-453
No abstract available.
Drainage*
;
Lung Abscess*
;
Lung*
;
Pneumothorax*
;
Suppuration*
9.Comparative Genetic Characterization of Plasmids of Agrobacterium Species Isolated in Korea.
Jung Hye KIM ; Yong Bum KOO ; Ki Young LEE ; Jae Kyu CHUNG
Yeungnam University Journal of Medicine 1984;1(1):41-48
The soil bacterium Agrobacterium tumefaciens is a plant pathogen that causes crown gall tumors by infecting the wounded dicotyledonous plants and subsequent integration of bacterial DNA into plant nuclear DNA. Virulent A. tumefaciens strains harbor a large Ti (tumor–inducing) plasmid that carries genes essential for tumorigenesis. In the present study, 13 strains (Malus pumila Mill; A₁₋₃, Populus monilifera; W₁₋₆, Populus tomentiglandlosa; P₁₋₃ and Rosa species; R₁) of Agrobacterium isolated in korean crown gall tumors and plasmids were observed in 6 strains (W₂, W₃, W₆, P₁, P₃ and A₂). The test for crown gall tumor formation was resulted only in ATCC15955 and KW2 strains inoculated into the stem of sun flower and the development was observed for 4 and 6 weeks after inoculation. Above two Ti plasmids (pTi) were purified by cesium chloride-ethidium bromide density gradient centrifugation and digested with restriction enzyme and fragments of pTiATCC15955 and pTiKW₂ observed by EcoR I ; 25&27, Hind III ; 23&21, BamH I ; each 20 and Hpa I ; 12&27. And sizes of pTiATCC15955 and and pTiKW₂ calculated as 200 and 87 kbases. Octopine was isolated from tumor tissue (W₁₋₆ and P₁₋₃) and these strains confirmed as octopine type.
Agrobacterium tumefaciens
;
Agrobacterium*
;
Carcinogenesis
;
Centrifugation, Density Gradient
;
Cesium
;
DNA
;
DNA, Bacterial
;
Flowers
;
Korea*
;
Plant Tumor-Inducing Plasmids
;
Plant Tumors
;
Plants
;
Plasmids*
;
Populus
;
Rosa
;
Soil
;
Solar System
;
Wounds and Injuries
10.Eruptive Vellus Hair Cysts in Association with Hypomelanosis of Ito with Turner's Syndrome.
Sook Jung YUN ; Jee Bum LEE ; Young Ho WON ; Seung Chul LEE
Annals of Dermatology 2000;12(4):283-285
A 24-year Korean woman presented with bizarre pigmentary skin changes. Eruptive vellus hair cysts (EVHC) were observed in conjunction with Hypomelanosis of Ito (HI). Also, the karyotype of 45XO with typical clinical symptoms of Turner's syndrome was detected in this patient, which has been rarely reported in HI as a chromosomal defect. EVHC may manifest as a rare skin manifestation of Hl.
Female
;
Hair*
;
Humans
;
Hypopigmentation*
;
Karyotype
;
Skin
;
Skin Manifestations
;
Turner Syndrome*