1.Comparison of Radiation Adaptive Responses in Peripheral Lymphocytes of Patients Undergoing Tc-99m MDP and Tc-99m DTPA Scintigraphies.
Hee Seung ROM ; Ming Hao LI ; Jung Jun MIN ; An Sung KWON ; Ji Yeul KIM
Korean Journal of Nuclear Medicine 2000;34(3):252-259
PURPOSE: The purpose of this study was to compare the radiation adaptive response (RAR) in peripheral lymphocytes (PL) of patients induced by Tc.-99m MDP and Tc-99m DTPA scintigraphies. MATERIALS AND METHODS: Lymphocytes from 45 patients (25 males, 20 females, mean age 44+/-18 years) were collected before and after scintigraphies using 740 MBq Tc-99m MDP (n=22) or Tc-99m L)TPA (n=23). Lympho-cytes from 20 controls (12 males, 8 females, mean age 43+/-7 years) were also callected. They were exposed to challenge dose of 2 Gy gamma-rays using a Cs-137 cell irradiator, Number of ring-form (R) and dicentric (D) chromosomes was counted under the light microscope. From them a representative score, Ydr, was calculated as Ydr=(D+R)/cells. Adaptation index (AI) was defined as difference of Ydr between unconditioned and conditioned lymphocytes. Ydr was also measured after an administration of cyclohexi-mide (CHM), a protein synthesis inhibitor, before challenge dose. RESULTS: RAR was induced in both groups of patients. CHM abolished the adaptive response in both groups. AI of Tc-99m MDP group was significantly higher than that of Tc-99m DTPA group. CONCLUSION: Tc-99m MDP induced RAR was more prominent than those induced by Tc-99m DTPA.
Chromosome Aberrations
;
Female
;
Humans
;
Lymphocytes*
;
Male
;
Pentetic Acid*
;
Technetium Tc 99m Medronate*
2.Fracture of the Capitellum Humeri: A report of two cases.
Young Bok JUNG ; Jae Kwang YUM ; Young Jae BAE ; Ho Sung RYU ; Tae Yeul YOO
The Journal of the Korean Orthopaedic Association 1998;33(6):1607-1610
Fractures of the capitellum humeri are rare and the recommendations for treatment vary. It can involve a significant portion of the articular surface, rendering the elbow joint unstable. In this situation, it is desirable to reduce and internally fix the capitellar fragment, because this restores the articular surface and augments joint stability. We experienced two cases of capitellar fractures which one case was spontaneously anatomical reduced and the other case was treated by open reduction. In one case the capitellar fragment was spontaneous reduced to a stable position although it was noticed radiographically as an unstable displaced fracture preoperatively. The other case was treated by open reduction and internal fixation with 3.5mm, small, AO, cannulated screw and K-wire. Both cases are reported here with references.
Elbow Joint
;
Joints
3.Central Retinal Artery Obstruction in Protein S Deficiency.
Sung Bok LEE ; Yong Jun YUN ; Jung Yeul KIM
Journal of the Korean Ophthalmological Society 2008;49(12):2017-2020
PURPOSE: To report a case of central retinal artery obstruction (CRAO) caused by protein S deficiency. CASE SUMMARY: A 36-year-old man presented with acutely reduced visual acuity in the right eye. The patient had no other diseases such as diabetes mellitus or hypertension. The visual acuity was 20/20 in the right eye and light perception in the left eye. Afferent pupillary defect was observed in theleft eye. Fundus examination showed diffuse retinal opacification and a cherry-red spot at the macula. Thus the patient was diagnosed with CRAO in the left eye. There were no abnormal findings on routine hematologic tests including blood coagulation test. Protein C activity, antithrombin III activation, anticardiolipin antibody were within normal limits but protein S activity was decreased. Thus, the patient was diagnosed with CRAO with protein S deficiency. CONCLUSIONS: Coagulation factors such as protein S need to be measuredin cases of CRAO in young patients without medical problems.
Adult
;
Antibodies, Anticardiolipin
;
Antithrombin III
;
Blood Coagulation Factors
;
Blood Coagulation Tests
;
Diabetes Mellitus
;
Eye
;
Hematologic Tests
;
Humans
;
Hypertension
;
Light
;
Protein C
;
Protein S
;
Protein S Deficiency
;
Pupil Disorders
;
Retinal Artery
;
Retinaldehyde
;
Visual Acuity
4.Central Retinal Artery Obstruction in Protein S Deficiency.
Sung Bok LEE ; Yong Jun YUN ; Jung Yeul KIM
Journal of the Korean Ophthalmological Society 2008;49(12):2017-2020
PURPOSE: To report a case of central retinal artery obstruction (CRAO) caused by protein S deficiency. CASE SUMMARY: A 36-year-old man presented with acutely reduced visual acuity in the right eye. The patient had no other diseases such as diabetes mellitus or hypertension. The visual acuity was 20/20 in the right eye and light perception in the left eye. Afferent pupillary defect was observed in theleft eye. Fundus examination showed diffuse retinal opacification and a cherry-red spot at the macula. Thus the patient was diagnosed with CRAO in the left eye. There were no abnormal findings on routine hematologic tests including blood coagulation test. Protein C activity, antithrombin III activation, anticardiolipin antibody were within normal limits but protein S activity was decreased. Thus, the patient was diagnosed with CRAO with protein S deficiency. CONCLUSIONS: Coagulation factors such as protein S need to be measuredin cases of CRAO in young patients without medical problems.
Adult
;
Antibodies, Anticardiolipin
;
Antithrombin III
;
Blood Coagulation Factors
;
Blood Coagulation Tests
;
Diabetes Mellitus
;
Eye
;
Hematologic Tests
;
Humans
;
Hypertension
;
Light
;
Protein C
;
Protein S
;
Protein S Deficiency
;
Pupil Disorders
;
Retinal Artery
;
Retinaldehyde
;
Visual Acuity
5.Full Thickness Macular Holes Associated with Terson Syndrome.
Sung Bok LEE ; Sang Hyuk KIM ; Jung Yeul KIM
Journal of the Korean Ophthalmological Society 2008;49(7):1194-1197
PURPOSE: To report a case of a full-thickness macular hole caused by Terson syndrome. CASE SUMMARY: A 49-year-old man presented to our clinic with decreased visual acuity in the right eye after a subarachnoid hemorrhage due to spontaneous rupture a middle cerebral artery aneurysm. On the first examination, the corrected visual acuity was hand movement in the right eye and 1.0 in the left eye. There was massive vitreous hemorrhage in the right eye. In the left eye, there was no abnormal ocular finding. He was diagnosed with vitreous hemorrhage due to Terson syndrome and waited for the spontaneous absorption of the vitreous hemorrhage. Six months later, the vitreous hemorrhage was considerably absorbed, but a macular hole was observed. OCT scans showed a full-thickness macular hole with an epiretinal membrane.
Absorption
;
Epiretinal Membrane
;
Eye
;
Hand
;
Humans
;
Intracranial Aneurysm
;
Middle Aged
;
Retinal Perforations
;
Rupture, Spontaneous
;
Subarachnoid Hemorrhage
;
Visual Acuity
;
Vitreous Hemorrhage
6.The Effect of Pretreated Pancronium with Subpsralytic Dose on Neuromuscular Blocking Onset.
Jung Yeul RHA ; Soon Im KIM ; Sung Yell KIM
Korean Journal of Anesthesiology 1985;18(2):156-160
This study was undertaken to investigate the effect of subparalytic doses of pancuronium on the its onset time of action during induction before endotracheal intubation. The patients were composed of 20 healthy female and 20 male adults which were ASA class l and ll. At the time of intubation, the control group received a pancuronium 0.08mg/kg as a single bolus after a 2.5% thiopental sodium 5mg/kg injection, and the pretreatment group received subparalytic dose of pancuronium 0.015mg/kg before the thiopental sodium injection and then followed by pancuronium 0.08mg/kg 3 minutes later. The degree of neuromuscular transmission was measured using the train of four stimulation of the ulnar nerve repeated every 20 seconds, and the time was measured when the 1st twitch height(T1) was changed to 85%, 75%, 50% and 25%. The results were as follows; the onset time of neuromuscular blocking action was quicker in female patients than in male patients, and was significantly more rapid in both sexes in the pretreated group by 23.3 to 63.8% compared to the control group.
Adult
;
Female
;
Humans
;
Intubation
;
Intubation, Intratracheal
;
Male
;
Neuromuscular Blockade*
;
Pancuronium
;
Thiopental
;
Ulnar Nerve
7.A Case of Intravitreal Voriconazole for the Treatment of Drug-resistant Penicillium Endophthalmitis.
Sung Bok LEE ; Chang Jun PARK ; Jung Yeul KIM
Journal of the Korean Ophthalmological Society 2007;48(11):1583-1587
PURPOSE: To report a case of a drug-resistant Penicillium endophthalmitis that was treated with intravitreal voriconazole injection. CASE SUMMARY: A 73-year-old male who developed endophthalmitis after cataract surgery was treated with intravitreal vancomycin and ceftazidime injection after aqueous and vitreous cultures were done. The condition were not improve after intravitreal injection, and the culture showed Penicillium species. Fungal endophthalmitis was diagnosed and pars plana vitrectomy, intraocular lens removal, and intravitreal amphotericin B injection were performed. However, a progressive worsening of the ocular condition was observed, and the patient was transferred to our hospital. At initial visit, the best corrected visual activity was hand movement. The hypopyon and thick exudative membrane filled the anterior chamber. Pars plana vitrectomy and intravitreal voriconazole injection were performed under the diagnosis of drug-resistant Penicillium endophthalmitis. The condition improved after the operation, and there was no recurrence of endophthalmitis until four months after vitrectomy. CONCLUSIONS: Voriconazole is useful in the treatment of drug-resistant fungal endophthalmitis.
Aged
;
Amphotericin B
;
Anterior Chamber
;
Cataract
;
Ceftazidime
;
Diagnosis
;
Endophthalmitis*
;
Hand
;
Humans
;
Intravitreal Injections
;
Lenses, Intraocular
;
Male
;
Membranes
;
Penicillium*
;
Recurrence
;
Vancomycin
;
Vitrectomy
8.A Case of Multiple small cell carcinoma in Esophagus and Cardia.
Won Hyuk SONG ; Sai Hyun PAIK ; Sung Chae JUNG ; Jae Sun KIM ; Yeul Hong KIM ; Jin Hai HYUN
Korean Journal of Gastrointestinal Endoscopy 1990;10(1):37-40
Small cell carcinoma does originate from APUD cells of any parts of the body. Usually the cases discovered in the lung and have poor prognosis. In esophagus only about 100 cases are reported world widely after McKneown reports in 1952 and only 2 cases were reported in Korea. There was a cese of small cell carcinoma developed multiple lesions in esophagus but no reports said that small cell carcinoma developed syncronously in esophagus and other organs. We are to report a case that showed a multiple lesions in esophagus and cardia. The patient 60 yeata old man, has suffered from the substernal discomfort and significant weight loss for one month.
APUD Cells
;
Carcinoma, Small Cell*
;
Cardia*
;
Esophagus*
;
Humans
;
Korea
;
Lung
;
Prognosis
;
Stomach
;
Weight Loss
9.Preoperative Cisternoscintigraphy As a Guide to Therapeutic Decision Making for Cystic Subdural Hygroma.
Sung Min KIM ; Hee Seung BOM ; Ho Chun SONG ; Jung Jun MIN ; Hwan Jeong JEONG ; Ji Yeul KIM
Korean Journal of Nuclear Medicine 2000;34(4):366-369
We report a case of a patient with cystic subdural hygroma who underwent pre-operative Tc-99m DTPA cistrenoscintigraphy to determine the course of operation. A 68-year-old female was admitted to the department of neurosurgery because of acute subarachnoid hemorrhage. After emergency ventricular drainage, the hydrocephalus and cystic subdural hygroma in the right fronto-temporal area developed. She underwent Tc-99m DTPA cisternoscintigraphy to evaluate the type of hydrocephalus, which revealed obstructive communicating hydrocephalus and the communication between the subdural hygroma and the subarachnoid space. As a result of these findings, she underwent the ventriculo-peritoneal shunt operation without removal of the subdural hygroma. Post-operative brain CT showed nearly normalized shape and size of the right ventricle and disappearance of subdural hygroma. We recommend the pre-operative cisternoscintigraphy in patients with complex hygroma to evaluate the communication between subdural hygroma and the subarachnoid space.
Aged
;
Brain
;
Decision Making*
;
Drainage
;
Emergencies
;
Female
;
Heart Ventricles
;
Humans
;
Hydrocephalus
;
Lymphangioma, Cystic
;
Neurosurgery
;
Pentetic Acid
;
Subarachnoid Hemorrhage
;
Subarachnoid Space
;
Subdural Effusion*
;
Ventriculoperitoneal Shunt
10.Radiologic Findings in Hydrated Hydrogel Buckles.
Sung Bok LEE ; Nam Ho LEE ; Young Joon JO ; Jung Yeul KIM ; Yeon Hee LEE ; Song Soo KIM
Journal of the Korean Radiological Society 2008;59(5):299-302
Hydrogel buckles, which are used in scleral buckling surgery for retinal detachment, have been associated with late complications after successful retinal reattachment surgery, including strabismus, extraocular motility restriction, extrusion through the eyelid or conjunctiva, intraocular erosion, and scleral erosion. Hydrogel buckles sometimes appear as well-marginated, circumferential, lobulating, contoured cystic masses mimicking orbital cysts on orbital CT or MRI. We report the radiologic findings in 5 patients whose hydrogel buckles needed to be differentiated from orbital cysts.
Conjunctiva
;
Eyelids
;
Foreign Bodies
;
Humans
;
Hydrogel
;
Orbit
;
Retinal Detachment
;
Retinaldehyde
;
Scleral Buckling
;
Strabismus
;
Tomography, X-Ray Computed