1.Prevalence of Syphilis in Normal Population in Korea ( 1987 - 1991 ).
Yeon Sang CHOI ; Hee Joon YU ; Sook Ja SON
Korean Journal of Dermatology 1994;32(5):866-871
BACKGROUND: According to the areas and people that are examined, there are many differences in the prevalence of syphilis in Korea. However, the reactive rate of the serologi test for syphilis showed an increase in the 1960s, and it has deerea@sed from the beginning of the 1970s. OBJECTIVE: Comparing the results of tke serologic test for syphilis which lotad been performed for the 5 years(1987-1991) on the physical examines and pregnant women who were considered as healthy, with the results with normal people, who were considered as healthy, which had been already reported, we tried to observe the change of reactive rate of serologic test for syphili. METHODS: The serologic test for syphilis, including serum VDRL test and serum TPHA test, were carried out on 25,254 healthy adults(20,405 were physical examineea eamined at National Medical Center and 4,849 were pregnant women delivered at National Medical Cer ter). RESULTS: The reaetive rate of serum VDRL test was 0.8% in 25,25 the althy adults(physical examinees 0.8%, pregnant women 0.7%). There were no stistically differerces between the annual incidences. 85.5% of VDRL-reactive subjects showed low VDRL titers(below 1:4) by the quantitative serum VDRL test, The biologic false positive reaction of serum VDRL test was 29(19.5%) in 149 VDRL-reactive subjects, using serum TPHA test as a standard. CONCLUSION: This study suggested thai, there was a decrease in the prevslence of syphilis in Korea.
Asian Continental Ancestry Group
;
False Positive Reactions
;
Female
;
Humans
;
Incidence
;
Korea*
;
Pregnant Women
;
Prevalence*
;
Serologic Tests
;
Syphilis*
2.Symptomatic epidural lipoma.
Chang Uk CHOI ; Joon Min SONG ; Dong Yeon KIM
The Journal of the Korean Orthopaedic Association 1992;27(4):1132-1136
No abstract available.
Lipoma*
3.Therapeutic Effect of Topical Ciclopiroxolamine on Onychomycosis.
Seung Yeon LEE ; Yeon Sang CHOI ; Hee Joon YU ; Sook Ja SON
Korean Journal of Dermatology 1995;33(3):504-509
BACKGROUND: Ciclopiroxole.minsolution or cream is the topical in imycotic agent which has been known to have the ability to penetrate the horny skin and nail keratin. OBJECTIVES: The purpose of this study was to evaluate the pierapeutic effect of 1% ciclopiroxolamine solution on onychomycosis. METHODS: 1% ciclopiroxolamie solution was applied topically to hentire surface of t,he diseased nail at least twice a day for 12 to 36 weeks according to the verity of nail involvement and degree of improvement in 21 cases of onychomycoses. RESULTS: 1. With only topical application of 1% ciclopiroxolamine solutior, 4 out of 21 cases(67%) showed 25% or more reduction of the affected nail area, and 8 out of 21 cases(38%) showed 50% or more reduction of the affected nail area. 2. There was no significant difference in the degree of improvem of according to the duration of disease. 3. Therapeutic effect was relat.ively high on Candida albicans, while it was relatively low on Aspergillus species. 4. 3 out of 7 cases of mild(up to 30%) involvement showed a 7% or more reduction of the affected nail, while 4 out of 6 cases of severe(60-100%) involvement showed a 25% or less reduction of the affected nail. 5. As side effects during the topical application of 1% ciclopiroxol nr ne solution, periungualer ythema appeared in 3 cases, and a burning sensation in 4 of 21 cases. CONCLUSION: 1% ciclopiroir olaniine solution could be tried as an effctive therapeutic agent on onychomycosis for the patient who would not be tolerable to oral an ifiigal medication for associated systemic diseases or who does not want oral medication.
Aspergillus
;
Burns
;
Candida albicans
;
Humans
;
Onychomycosis*
;
Sensation
;
Skin
4.A Case of Bilateral Herprs Zoster.
Seung Yeon LEE ; Yeon Sang CHOI ; Hee Joon YU ; Sook Ja SON
Korean Journal of Dermatology 1994;32(6):1119-1122
Herpes zoster is characterized by several groups of vesicles situateu unilaterally within the distribution of the cranial or spinal nerve coming from one posterior ganglion Biateral involvement and recurrence are rare, and zoster involves two widely separated regions at on time are even rarer. We report a case of bilateral eupes zoster. A 5-years-old female patient was presented with painful bilateral grouped vesicles on an erythematous base along the dermatome of Lt T2 and Rt T5. Tzanck smear revealed multinucleated giant cells, and histopathologic findings were consistent with herpetic infection. She was successfully treated by administration of acyclovir without any significant cornplications.
Acyclovir
;
Female
;
Ganglion Cysts
;
Giant Cells
;
Herpes Zoster*
;
Humans
;
Recurrence
;
Spinal Nerves
5.Platelet Serotonin Level and Psychological Features of the Suicidal Attempters.
Hee Yeon JEONG ; Young Joon KWON ; In Joon PARK ; Eui Jung CHOI ; Se Yong HONG ; Hyuk Hee JIN
Journal of the Korean Society of Biological Psychiatry 1999;6(1):81-88
OBJECTIVES: Significant progress has been made in understanding psychosocial, psychological, and environmental factors associated with suicide. However it is only recently that attention has been paid to the understanding of the neurobiology of suicide. The aim of this study was to examine the relationship between platelet serotonin level and suicidal behavior and psychological features of the suicidal attempters. METHODS: After a suicidal attempt platelet serotonin level was measured from 21 patients and compared it with those from depression patients and normal controls. Also MMPI, HAM-D, Barratt impulsiveness scale(BIS) were done to evaluate their psychological features. RESULTS: 1) There was no significant difference in sex ratio of the suicidal attempters. 2) There was no significant difference in platelet serotonin levels among three groups. 3) The analysis of MMPI revealed that the scores of D, Hs, Pt in clinical scales were significantly higher in suicide patients and scores of D, Pa, Si were in depression patients. 4)The HAM-D score was significantly higher in depression and suicide patients, especially in depression patients. 5) The analysis of Barratt impulsiveness scale revealed that the scores of nonplanning, motor and cognitive impulsiveness scale were significantly higher in suicide patients. CONCLUSIONS: There was no significant difference in platelet serotonin levels among three groups. However the analysis of psychological features revealed significant differences. Therefore we concluded that psychological examinations are benefit to evaluate the suicidal tendency.
Blood Platelets*
;
Depression
;
Humans
;
MMPI
;
Neurobiology
;
Serotonin*
;
Sex Ratio
;
Suicide
;
Weights and Measures
6.5 Cases of Pressure Alopecia after Tympanomastoidectomy.
Yeon Sang CHOI ; Young Gon BAIK ; Hee Joon YU ; Sook Ja SON ; Yong Jae KIM
Korean Journal of Dermatology 1994;32(2):352-357
Pressure alopecia can occur after prolonged pressure on the scalp with the head fixed in one position. We have repor ted 5 cases of pressure alopecia, occurring over the contralateral temporoparietal 1 area after tympanomastoidectomy due to chronic ot.itis media. Total times of operations were from 4 hours to 7 hours. Four of the 5 patients experienced scalp pain during the early postoperative period and one of them showed large bulla formation. Loss of hairs followed between the 14th and 36th postoperative day, and new hairs began to grow 2 or 3 months after the operation.
Alopecia*
;
Hair
;
Head
;
Humans
;
Postoperative Period
;
Scalp
7.A Case of Trichophyton rubrum Infection showing Unusual Clinical Manifestation.
Yeon Sang CHOI ; Soo Keun LEE ; Hee Joon YU ; Sook Ja SON
Korean Journal of Dermatology 1995;33(3):585-589
Trichophyton rnbrum is a.nthropophilic, and the most common and widely distributed dermato phyte of man. Characterisic lions are circular, usually sharplyn ginated, slightly erythematous, dry, scaly patches with a raised edge. Progressive central clearin produces annular outlines. Other variants are reported, such as granulomatous, bullous or verucius. We reported a case of Trichophyton rubrum infection showing an unusual clinical manifest tin. The skin leison showed multiple discrete brownishouni macules with a fine scale on both hi lower legs, dorsum of feet and buttocks. Central clearing and inflammed border were not not. On KOH mount, fungal hyphae were noted and Techophyton rubrum was isolated on the funu culture.
Buttocks
;
Foot
;
Hyphae
;
Leg
;
Lions
;
Skin
;
Tin
;
Trichophyton*
8.Ultrasound Guided Biopsy of Malignant Focal Liver Lesions: Comparison of Automated Gun Biopsy with Fine Needle Aspiration Biopsy.
Byung Ihn CHOI ; Joon Koo HAN ; Man Chung HAN ; Jeong Yeon CHO
Journal of the Korean Radiological Society 1995;33(3):389-394
PURPOSE: To compare the efficacy and safety of ultrasound guided automated gun biopsy with fine needle aspiration biopsy of focal liver lesions. MATERIALS AND METHODS: We performed 32 automated gun(19.5G Autovac Biopsy Needle) biopsies and 27 fine needle aspiration(22G Westcott Style Biopsy Needle) biopsies in 48 patients with malignant focal liver lesion under the guidance of ultrasound. We compared the "positive for malignancy rate" and "pathologic diagnosis rate" of both methods with final diagnosis, and the rate of complications. RESULTS: The "positive for maiignancy rate" of automated gun biopsy and needle aspiration are 84.4%(27/32) and 66.7%(18/27) respectively(p=0.11). The "pathologic diagnosis rate" are 84.4%(27/32) and 55.6%(15/27) with significant statistical difference(p<0.05). And there is no difference of the rates of significant complications. CONCLUSION: When compared with the fine needle aspiration biopsy, ultrasound-guided automated gun biopsy is safe and more effective method for malignant focal liver lesion.
Biopsy*
;
Biopsy, Fine-Needle*
;
Diagnosis
;
Humans
;
Liver*
;
Needles
;
Ultrasonography*
9.A Mycological Study on Dermatophytoses in Seoul During the Peroid 1985 - 1991.
Hee Joon YU ; Yeon Sang CHOI ; Young Gon BAIK ; Sook Ja SON
Korean Journal of Dermatology 1994;32(1):24-33
BACKGROUND: Dermatophytoses show marked differences in their incidences, distributions, and causative organisms by age, sex, occupations, environmental conditions and geographic distributions. OBJECTIVE: We evaluated the recent distributions of dermatophytes and compared them with the previous reports in Seoul. METHODS: We evaluated the incidences of dermatophytes according to the patient's age and sex, isolated month, and the infection sites with 387 strains of dermatophytes isolated from the various forms of dermatophytoses during the period from August 1985 to July 1991 in Seoul. RESULTS: T. rubrum was the most prevalent dermatophyte in all age groups except the first decade. The incidence of M. canis was high in age groups below 20 years old relatively high incidences of T. mentagrophytes and T. interdigitale in age groups over 30 years old. Dermatophytes were frequently isolated in summer season, but the incidence of M. canis was relatively high in October and December. T. rubrum was the most prevalent dermatophyte from all forms of dermatophytoses except tinea capitis, but the incidence of T. rubrum was relatively low in tinea corporis. The incidence of T. mentagrophytes was relatively high in tinea unguium and tinea manus, and M. canis was isolated only in tinea corporis and tinea capitis. From the cases showing more than two forms of dermatophytoses. T. rubrum was isolated for the most part. CONCLUSION: This study suggested that there was a rise in the cases of t. rubrum infections in Seoul and in recent years the prevalence of M. canis infections has markedly increased but those of E. floccosum and t. mentagrophytes have decreased.
Adult
;
Arthrodermataceae
;
Humans
;
Incidence
;
Occupations
;
Onychomycosis
;
Prevalence
;
Seasons
;
Seoul*
;
Tinea Capitis
;
Tinea*
;
Young Adult
10.Dexmedetomidine Use in Patients with 33degrees C Targeted Temperature Management: Focus on Bradycardia as an Adverse Effect.
Hyo Yeon SEO ; Byoung Joon OH ; Eun Jung PARK ; Young Gi MIN ; Sang Cheon CHOI
Korean Journal of Critical Care Medicine 2015;30(4):272-279
BACKGROUND: This study aimed to investigate bradycardia as an adverse effect after administration of dexmedetomidine during 33degrees C target temperature management. METHODS: A retrospective study was conducted on patients who underwent 33degrees C target temperature management in the emergency department during a 49-month study period. We collected data including age, sex, weight, diagnosis, bradycardia occurrence, target temperature management duration, sedative drug, and several clinical and laboratory results. We conducted logistic regression for an analysis of factors associated with bradycardia. RESULTS: A total of 68 patients were selected. Among them, 39 (57.4%) showed bradycardia, and 56 (82.4%) were treated with dexmedetomidine. The odds ratio for bradycardia in the carbon monoxide poisoning group compared to the cardiac arrest group and in patients with higher body weight were 7.448 (95% confidence interval [CI] 1.834-30.244, p = 0.005) and 1.058 (95% CI 1.002-1.123, p = 0.044), respectively. In the bradycardia with dexmedetomidine group, the infusion rate of dexmedetomidine was 0.41 +/- 0.15 microg/kg/h. Decisions of charged doctor's were 1) slowing infusion rate and 2) stopping infusion or administering atropine for bradycardia. No cases required cardiac pacing or worsened to asystole. CONCLUSIONS: Despite the frequent occurrence of bradycardia after administration of dexmedetomidine during 33degrees C target temperature management, bradycardia was completely recovered after reducing infusion rate or stopping infusion. However, reducing the infusion rate of dexmedetomidine lower than the standard maintenance dose could be necessary to prevent bradycardia from developing in patients with higher body weight or carbon monoxide poisoning during 33degrees C targeted temperature management.
Atropine
;
Body Weight
;
Bradycardia*
;
Carbon Monoxide Poisoning
;
Dexmedetomidine*
;
Diagnosis
;
Emergency Service, Hospital
;
Heart Arrest
;
Humans
;
Hypothermia, Induced
;
Logistic Models
;
Odds Ratio
;
Retrospective Studies