1.Clinical Observation on the Effect of Psychological Intervention Combined with Fresh Motherwort Capsule in the Treatment of Postpartum Lochiorrhea and Waist Pain
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):80-82
Objective To investigate the clinical effect of psychological intervention combined with fresh motherwort capsule in the treatment of postpartum lochiorrhea and waist pain. Methods 86 cases of postpartum lochiorrhea and waist pain patients admitted to our hospital from January 2016 to December 2016 were selected. The patients were divided into observation group and control group according to the random number table method, 43 cases in each group. The control group was treated with routine nursing combined with the treatment of uterine stopping granule, while the observation group was treated with psychological intervention combined with the fresh motherwort capsule. After 1 month of intervention, the postoperative morbidities (the amount of lochia, the duration of lochia, the blood, and the bloody) and the abdominal pain and the condition of anxiety and depression before and after treatment were statistically compared between the two groups. Results Two groups of lochia status and waist pain were compared before treatment, and there was no statistically significant difference; After 1 month of intervention, the postoperative morbidities (the amount of lochia, the duration of lochia, the blood, the bloody) and the scores of abdominal pain in the observation were lower than those in the control group. And there was statistically significant difference; After 1 month's intervention, the anxiety and depression scores of the observation group were lower than that of the control group; the difference was statistically significant (P<0.05). Conclusion The treatment of psychological intervention combined with fresh motherwort capsules can reduce postpartum lochia amount of bleeding, shorten the duration of lochia, reduce abdominal pain, improve patient's psychological state, and promote postpartum recovery.
2.Prevalence and risk factors of diabetic retinopathy in type 2 diabetic inpatients
International Eye Science 2015;(2):337-339
AlM: To investigate the risk factors of diabetic retinopathy ( DR) in type 2 diabetes patients.METHODS:A total of 380 cases of type 2 diabetes were selected from January 2014 to June 2014, divided into DR group (126 cases) and non-diabetic retinopathy ( NDR) as control group (254 cases), all patients were underwent medical history, physical examinations, laboratory and assistance examinations. The prevalence and single factor and multiple factors of DR were analysed by the logistic regression model.RESULTS: The univariate logistic regression analysis showed that DR was associated with diabetes duration, systolic blood pressure, triglyceride, total cholesterol, low - density lipoprotein, urine protein, intraocular pressure, carotid intima - media thickness, peripheral neuropathy disease was the related risk factors for DR. ln multiple logistic regression analysis, only duration was the related risk factors for DR.CONCLUSlON:The occurrence of DR is the outcome of combined action of multiple factors, duration is an independent risk factor for occurrence of DR.
3.The effect evaluation of bronchodilation agents in the treatment of childrens with airway hyperresponsive dis-ease
Chinese Journal of Primary Medicine and Pharmacy 2013;20(z1):1-3
Objective To objectively evaluated of the efficacy of bronchodilation agent by using pulmonary function .Methods 104 childrens with airway hyperresponsive diseases who saw doctor at the Guangdong Women and Children′s Hospital,aged 0~6 years.They were classified into three groups:salbutamol group(n=36);ipratropium bromide group(n=32) and two drugs group(n =36).Each group received salbutamol or ipratropium bromide or both.Then tidal breathing flow-volume loop and parameters were obtained before and after aerosol inhalation to evalu-ate the effects of drugs .Results There were significant improvement in each group after the inhalation of bronchodi -lators.Conclusion The two drugs of Salbutamol and ipratropium bromide can be used as the selective drugs of bron -chodilation .
4.Analysis of the relationship between serum HBV-DNA And hepatic fibrosis
International Journal of Laboratory Medicine 2015;(3):326-327,330
Objective To analyze the relationship between serum HBV-DNA and hepatic fibrosis in patients with hepatitis B. Methods Serum HBV-DNA load and hepatic fibrosis hyaluronic acid (HA),Ⅲ procollagen N terminal peptide(PⅢNP),laminin (LN),Ⅳ collagen(Ⅳ-C)of 154 cases were detected by real-time fluorescence quantitative PCR and chemiluminescence method. Statistical analysis of the correlation between HBV-DNA load and hepatic fibrosis indicator was performed.Results The data of HBV-DNA load after taking lg value was 5.49±1.39;The serum concentration of hepatic fibrosis HA was (166.95±148.20)ng/mL,PⅢNP was (12.14±7.37)ng/mL,Ⅳ-C was (65.29±45.48)ng/mL,LN was (59.52±35.67)ng/mL.The difference between experimental group and control group in hepatic fibrosis was significant(P <0.05).Serum HBV-DNA only correlated with LN(r=0.284,P =0.015).Conclusion There is no significant correlation between serum HBV-DNA and hepatic fibrosis in hepatitis B pa-tients.Anti-fibrosis treatment should also be strengthened for hepatitis B patients in the course of antiviral treatment.
5.Applications of 18F-Fluorodexyglucose Positron Emission Tomography on the Diagnosis and Treatment of Carcinoma of Large Intestine
Chinese Journal of Bases and Clinics in General Surgery 2003;0(02):-
Objective To introduce the current study on 18F-fluorodexyglucose positron emission tomography (18F-FDG PET) scanning in diagnosis and treatment of carcinoma of large intestine.Methods The literatures about 18F-FDG PET scanning in diagnosis and treatment of carcinoma of large intestine in recent years were reviewed.Results 18F-FDG PET scanning is superior to CT and MRI in identificating carcinoma of large intestine recurrence, metastasis in the early stage after operation and staging carcinoma of large intestine.Conclusion 18F-FDG PET scanning may be one of the accessory examinations in carcinoma of large intestine and may be helpful for the choice of treatment.
6.THE PRELIMINARY STUDIES ON ANTI-TUMOR ACTIVITY OF GINKGO ALBUMIN AND ITS MECHANISM
Qianchun DENG ; Wen HUANG ; Bijun XIE
Acta Nutrimenta Sinica 1956;0(03):-
Objective:To study the anti-tumor activity of ginkgo albumin (GA) and its mechanism. Method: Molecular weight of GAⅡa was detected by MS (mass spectrum). The antioxidative effect of GA was studied by deoxyribonucleic acid method and nitroblue tetrazolium (NBT) photo-reduction, and the anti-tumor activity of GA on S180 sarcoma was studied both in vivo and in vitro. Results: Molecular weight of GAⅡa was 29 248u. GA had strong scavenging effect on superoxide radical and hydroxyl radical. The growth of S180 both in vitro and in vivo was inhibited significantly by GA. Conclusion: The anti-tumor activity of GA was probably related with its antioxidative effect.
7.Exploration and Reform of Infectious Disease Teaching
Cunliang DENG ; Yunjian SHENG ; Wen CHEN
Chinese Journal of Medical Education Research 2006;0(10):-
Problems and insufficiency in Infectious Disease teaching were analyzed and several improvement measures were proposed to emend the teaching outline,to strengthen the construction of teaching material,to improve teaching staff quality and to improve class and experiment teaching quality.
8.Teaching Experience of Anatomy,Histology and Embryology for Foreign Students
Jinbo DENG ; Dongming YU ; Shuguang WEN
Chinese Journal of Medical Education Research 2006;0(11):-
The methods and experiences of anatomy,histology and embryology teaching in English for foreign students are discussed in this article to exchange experiences with each other and progress together.
9.Diagnostic Value of Thirteen Types of Serum Tumor Markers for Lung Cancer in China:A Meta-Analysis
Ying PENG ; Zhenghua DENG ; Xianyong WEN
Journal of Modern Laboratory Medicine 2016;(1):96-100
Objective To evaluate diagnostic values of thirteen single and combined serum tumor markers in the diagnosis of lung cancer in Chinese people.Methods Chinese databases were searched systematically for prospective studies of serum tumor markers in Chinese patients with lung cancer and standard statistical methods for meta-analysis were applied.Results Thirty articles were selected containing thirteen types of molecular tumor markers and 4 393 people.The optimal serum marker was CEA+CA125+CYFRA21-1 with the combined sensitivity,specificity,positive likelihood ratio,negative likeli-hood ratio,the diagnostic odds ratio and the area under the summary receiver operating characteristic curve (AUC)was 87%[95% confidence interval (CI)0.81~0.91],93%(95% CI 0.89~0.95),11.8 (95% CI 7.84~17.7),0.15 (95% CI 0.10~0.21),81.3(95% CI 44.4~149.0)and 0.910,respectively.Conclusion There was improved diagnostic performance in combined markers than other individuals.Serum tumor marker CEA+CA125+CYFRA21-1 is the optimal biomarker for the diagnosis of lung cancer.
10.Establishment and Application of a Real-Time Quantitative PCR Assay for Detection of Campylobacter Jejuni in Human Feces
Yunpeng CHEN ; Wen LIN ; Jianping DENG
Journal of Modern Laboratory Medicine 2014;(5):85-88
Objective To establish a real-time quantitative PCR assay for the identification of Campylobacter jejuni in fecal samples.Methods Specific primers of the PCR were designed according to the conserved sequences of Campylobacterjeju-ni,and the real-time quantitative PCR assay was established.150 cases of fecal samples were tested by both culture and PCR methods.With the culture testing results as the reference standard,the sensitivity,specificity,accuracy and repetition of the real-time quantitative PCR were validated.Kappa test was used to estimate the difference between the two detection meth-ods.Results The standard carve of the real-time quantitative PCR assay fitted the equationY=-3.51Log(X)+37.09 (R2=0.996)well.The sensitivity,specificity,and accuracy of the established method were 92.4%,95.8% and 94%,respective-ly.The theoretical detection limit of the PCR method was 102 CFU/ml,and its reproducibility was good (CV<5%).Statisti-cal analysis demonstrated that the results of the two methods were consistent,and the consistent strength was very strong (Kappa=0.88,P<0.05).Conclusion The established real-time PCR method can assay the Campylobacterjejuni in human fecal samples rapidly and accurately.