1.Genu Varum, Both.
Journal of the Korean Medical Association 1999;42(6):610-615
No abstract available.
Genu Varum*
2.The Effect of theophylline on eotaxin mRNA expression in pulmonary epithelial cell line A549.
Min Soo HAN ; Jee Hong YOO ; Hong Mo KANG
Tuberculosis and Respiratory Diseases 2000;48(6):898-908
BACKGROUND: Eotaxin, a CC chemokine specific for eosinophils, is implicated in the pathogenesis of asthma recruiting eosinophils into the airways. Theophylline has been used for the treatment of asthma and rece was proposed to have an anti-inflammatory action. The aim of this study is to examine whether theophylline may inhibit the eosinophilic airway inflammation by reducing the expression of eotaxin. METHODS: The expression of eotaxin mRNA was assessed by Northern analysis in A549 cells 4 h after stimulation with TNF-α or IL-1β And then, theophylline was added to A549 cells stimulated with 0.1 ng/ml IL-1β. RESULTS: Eotaxin mRNA expression rates induced by 0.1, 1, 10 ng/mL TNF-α as compared with β-action were 7%, 22%, 28%, respectively. Eotaxin mRNA expression rates induced by 0.01, 0.1, 1, 10 ng/ml IL-1β as compared with β-action, were 10%, 42%, 63%, 72%, respectively. Eotaxin mRNA expression rates after addition of 0, 0.001, 0.01, 0.1 µM dexamethasone induced by 10 ng/mL TNF-α, as compared with β-action were 27%, 18%, 8%, respectively. Eotaxin mRNA expression rates after the addition of 0.001, 0.01, 0.1 mM dexamethasone induced by 0.1 ng/mL IL-1β, as compared with β -action, were 43%, 47%, 12%, 8%, respectively. Eotaxin mRNA expression rates after the addition of 0, 0.001, 0.01, 0.1, 1, 10 mM theophylline induced by 0.1 ng/mL IL-1β, as compared with β-action, were 48%, 40%, 33%, 22%, 16%, 14%, respectively. CONCLUSION: These results suggest that theophylline may reduce eosinophil infiltration of the airway at least in part by reducing the expression of eotaxin under the conditions of these experiments.
Asthma
;
Dexamethasone
;
Eosinophils
;
Epithelial Cells*
;
Inflammation
;
RNA, Messenger*
;
Theophylline*
3.Ganglion in extensor tendon of the hand: case report
Duke Whan CHUNG ; Jung Soo HAN ; Yong Girl LEE ; Ok Kyun AHN ; Soo Hong HAN
The Journal of the Korean Orthopaedic Association 1995;30(1):170-172
Ganglion is a common clinical entity, usually superficial in location, therefore easily diagnosed and most common tumors of the hand which represent 50 to 70% of all soft tissue tumors of the hand. The soft mucin filled cyst is attached to the adjacent underlying joint capsule, tendon, or tendon sheath. The most common ganglion is the ganglion on the dorsal side of wrist, with its origin at the scapulolunate ligament and is usually located between the extensor digitorum communis of the index finger and the extensor pollicis longus tendons. Intratendinous ganglion is very rare lesion that originates within the tendon, which has been reported 10 cases in earliest articles and 1 case in Korean article. We report one case of ganglion that arose within the extensor digitorum communis of the middle finger.
Fingers
;
Ganglion Cysts
;
Hand
;
Joint Capsule
;
Ligaments
;
Mucins
;
Tendons
;
Wrist
4.Comparison of Techniques for Correcting the Prominent Ear in Rabbits.
Jin Soo KO ; Seung Han KIM ; Seung Hong KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(5):1035-1039
The relative merits of cartilage scoring versus suturing in techniques for correcting the prominent ear remains a subject of debate among leading plastic surgeons. We compared a variety of echniques for correcting the prominent ear in 72 rabbit ears using scoring, horizontal mattress sutures, and combination scoring and suturing. The ears were splinted with a right-angle fold for 3 postoperative weeks, and the animals were sacrificed after 8 weeks. Suturing techniques in combination with scoring maintained an angulation significantly closer to the desired 90 degrees than cartilage scoring or cartilage suturing only(p<0.05). Histological analysis demonstrated a significant increase in cartilage hyperplasia by suturing alone, whereas the other techniques achieved only mild to moderate increases. We recommend cartilage scoring and suturing through skin incision on severe degrees of prominent ear, and cartilage needle scoring and buried suturing through slit incision on mile-to-moderate degrees of prominent ear.
Animals
;
Cartilage
;
Ear*
;
Hyperplasia
;
Needles
;
Rabbits*
;
Skin
;
Splints
;
Sutures
5.Tricuspid Regurgitation in Heart Diseases in Infants and Children.
Hye Kyung HAN ; Yong Soo YUN ; Chang Yee HONG
Korean Circulation Journal 1988;18(1):127-134
Doppler echocardiography was performed to evaluate the tricuspid regurgitation in 786 infants and children with heart disease. 3 Doppler methods were used. : The duration of systolic turbulence of tricuspid regurgitation in thr right atrium was evaluated by continuous wave Doppler method, the distance of systolic turbulence within right atrium from the tricuspid plane, by pulsed Doppler method and the retrograde systolic hepatic vein regurgitation, by color Doppler method. The following results were obtained. 1) Incidence of pan systolic tricuspid regurgitation in each disease were as follows. 68% of ECD, 66% of Ebstein's anomaly, 54% of pulmonary atresia, 50% of arrhythmia, 45% of ASD, 38% of TAPVR, 15% of VSD, 26% of TOF, 12% of PDA, 13% of normal children. 2) In about 90% of children with tricuspid regurgitation, hepatic vein regurgitation was detected by color Doppler echocardiography.
Arrhythmias, Cardiac
;
Child*
;
Ebstein Anomaly
;
Echocardiography, Doppler
;
Echocardiography, Doppler, Color
;
Heart Atria
;
Heart Diseases*
;
Heart*
;
Hepatic Veins
;
Humans
;
Incidence
;
Infant*
;
Pulmonary Atresia
;
Scimitar Syndrome
;
Tricuspid Valve Insufficiency*
6.Problems after Interlocking Intramedullary Nailing for Long Bone Fracture
Hong Jun HAN ; Kyung Younl JHON ; Sang Soo KIM
The Journal of the Korean Orthopaedic Association 1990;25(2):377-388
Interlocking nailing technique has many advantages in the fracture treatment. Such as the prevention of infection and devitalization by closed technique, stable intramedullary osteosynthesis, bone grafting effect of reaming debris, and early restoration of loading and function, comparing to the conventional intramedullary nailing. However, we met many problems during the operative procedure due to deficient concept and technique. We have checked the possible problems during and after the procedure of interlocking nailing for the tibia or femur fractures in 69 cases. 1. Sixty nine cases were consisted by 26 cases of femur fractures and 43 cases of tibia fractures. 2. The inadequate implant length was the most common error in the implant selection (4 cases in femur, 6 cases in tibia). 3. A new fragment was made in 12 patients(17%) during surgery, more commonly in the femur (9 cases), especially medial side and distal to the fracture line. 4. Bone shortening, angulation deformity or rotational deformity, caused by incomplete reduction, were developed more commonly in the tibia than in the femur. 5. Post-operative deep infection were developed in 2 cases(3%). 6. Delayed or non-union were developed in 18 cases(28%), who were followed for more than 3 months. 7. Circumferential wiring or bone grafting using semiclosed technique is thought to be useful to prevent delayed or nonunion when there is a wide gap between fractured fragments pre-operatively.
Bone Transplantation
;
Congenital Abnormalities
;
Femur
;
Fracture Fixation, Intramedullary
;
Fractures, Bone
;
Surgical Procedures, Operative
;
Tibia
7.Arthroscopic Adhesiolysis of Partial Knee Ankylosis
Dae Kyung BAE ; Sang Yeol CHO ; Soo Hong HAN
The Journal of the Korean Orthopaedic Association 1995;30(6):1685-1693
Partial knee ankylosis is a recognized complication of following open operative procedure, trauma and disease processes about the knee. Intraarticular trauma or surgical procedures such as TKR, synovectomy or patellar fracture were main source of intraarticular or extraarticular soft tissue adhesion and contracture were resulted from distal femoral and proximal tibial fractures. The purpose of this study is to report the value of arthroscopic adhesiolysis of partial knee ankylosis and to evaluate the clinical results of its application in various conditions. From October 1982 to December 1992, 56 cases in 54 patients who had severe limitation of motion in the knee joint following open operative procedure or trauma about the knee were treated by fibroarthrolysis under the arthroscopic control. For release of thick fibrous tissue, we used our designed blunt metal bar. The following results were obtained. There were 30 males and 24 females and the age at the time of release ranged from 20 to 69 years old(average 38.7 years old). The interval between last open operative procedure or trauma and arthroscopic adhesiolysis ranged from 3 months to 6 years(average 16 months). The interval between arthroscopic adhesionlyssis and the last follow up evaluation ranged from 1 year to 9 years(average 49 months), The average preoperative range of knee motion was 42.2 and the postoperative range of motion under the anesthesia was 115.5 and the average final knee range of motion at follow up was 101.3. So the average loss of motion between postoperative and final motion was 14.2. Complications were one case of patellar and tibial condylar fracture respectively. In the author's experience, arthroscopic adhesiolysis seems to be applied to the various condition of the partial knee ankylosis and the results are better than the other surgical procedures when it was performed early enough16).
Anesthesia
;
Ankylosis
;
Contracture
;
Female
;
Follow-Up Studies
;
Humans
;
Knee Joint
;
Knee
;
Male
;
Range of Motion, Articular
;
Surgical Procedures, Operative
;
Tibial Fractures
;
Tissue Adhesions
8.The compliance of hyperlipidemic patients according to therapeutic methods.
Soon Hee JEONG ; Kum Yae HAN ; Young Mi HAN ; Yeon Joo LEE ; Hong Soo LEE
Journal of the Korean Academy of Family Medicine 1993;14(1):1-8
No abstract available.
Compliance*
;
Humans
9.The compliance of hyperlipidemic patients according to therapeutic methods.
Soon Hee JEONG ; Kum Yae HAN ; Young Mi HAN ; Yeon Joo LEE ; Hong Soo LEE
Journal of the Korean Academy of Family Medicine 1993;14(1):1-8
No abstract available.
Compliance*
;
Humans
10.Femoral Head and Neck Fractures developed in Avascular Necrosis of the Femoral Head.
Hyung Ku YOON ; Duck Yun CHO ; Soo Hong HAN ; Yong Sub HAN ; Ki Sik NAM
Journal of the Korean Hip Society 2006;18(1):79-83
Femoral head and neck fractures during the course of avascular necrosis are rare with only few reports in the English literature. Moreover, there are very few reports on an analysis of the patterns of these fractures. Four cases of femoral head fracture caused by minor trauma, which were quite different from the crescent fractures during the course of avascular necrosis were analyzed in regard to the underlying disease, causes, sites, types, directions, pattern of fractures and the injury mechanism of the fractures. The results are reported with special regard to the pattern of the stress fracture of the femoral head and neck during the course of avascular necrosis.
Fractures, Stress
;
Head*
;
Neck*
;
Necrosis*