BACKGROUND: It has been known that androgenetic alopecia in both male and female is due to the role of the androgen hormone in the hair follicle, but the level of the androgen hormone in the plasma is controversial in relation with the development of the alopecia. OBJECTIVE: We have tried the clarify if there is any or no difference in the plasma levels of the hormones between the normal female and the patient with alopecia, because the range of the plasma DHEA-S and total testosterone in the normal female is very wide. METHODS: Plasma levels if the hormones were examined in 22 patients with female androgenetic alopecia and 20 normal females. RESULTS: 1. In DHEA-S, 21(95.5%) aut of 22 female androgenetic alopecia patients were in the normal range while 20(100%) of the 20 normal females were all within the normal range. However the mean value of the hormone(88.89+101.41 g/dl) in the patient group was significantly higher than that(82.18+44.03 g/dl) of the normal group(p<0.05). 2. In total testosterone, 17(94.4%) out of the 18 patents were in the normal range while 20 (100%) of 20 normal females were all within the normal range. However the mean value of the hormone(0.22+0.20ng/ml) in the patient group was significantly higher than that(0.08+0.09ng/ml) of the normal group(p<0.05). 3. As for distribution of DIEA S according to the age, the value of the patient group was higher than that of the normal group in all age groups studied. In the distribution of total testosterone according to age, there was no difference between the normal and the patient in the twenties. After the twenties, the testosterone levels were higher in the patients than the normal females. CONCLUSION: There were significant differences in mean values of plasma DHEA-S and total testosterone between the patients and the normal females although individuals in both groups were largely wit,hin normal range of the hormones.
Alopecia* ; Dehydroepiandrosterone Sulfate* ; Dehydroepiandrosterone* ; Female* ; Hair Follicle ; Humans ; Male ; Plasma* ; Reference Values ; Testosterone*

Microsporum ferrugineum was the most common cause of tinea captis in Korea until the middle of the 1970s, but this organism has been only rarely isolated from the scalp ringworm during recent years. We report, three cases of tinea capitis occurring in a 2-year-old male, a 10 year-old female and a 5-year-old male. From all three patients, Microsporum ferrugineum was isolated.
Child ; Child, Preschool ; Epidemiology ; Female ; Humans ; Korea ; Male ; Microsporum* ; Scalp ; Tinea Capitis* ; Tinea*

No Abstract Available.
Adenoma*

Malassezia intertrigo is a very rare clinical entity in which the clinical lesions occur in intertroginous areas as erythematous scaling macules and direct microscopic examinatons of scales reveal only large numbers of yeast forms of Malassezia organism. A 59-year-old man, developed brown, finely scaling macular lesions on the inguinal areas. Direct microscopy and culture of the scalings taken from the lesional areas of the patient revealed only oval forms of Malassezia organism.
Humans ; Intertrigo* ; Malassezia* ; Microscopy ; Middle Aged ; Weights and Measures ; Yeasts

A 12-year-old boy showed a slatecolored scaly patch on h; ight face for 2 months. Histopathologic findings showed basal vacuolations and dermal me arphages with only scanty lymphoid cells in the fat tissue layer. Besides the facial lesion, lesions of edematous localized erythema were noted on his right if and left buttock with similar mi rocopical findings. 6 months later the facial lesion was aggravated like a cellulitis, of which thc bevpsy findings were consistent with mycosis fungoides. The patient received chemotherapy aftei the diagonsis for one month before his termination. Because of the rarity of mycosis fungoides in childhood age and its un common cutaneous lesions, the case is reported.
Buttocks ; Cellulitis ; Child ; Dronabinol ; Drug Therapy ; Erythema ; Humans ; Lymphocytes ; Male ; Mycosis Fungoides* ; United Nations

Deep palmoplantar warts (Myrmecia) are frequently tender papules or plaques caused by HPV-1. Myrmecia are usually misdiagnosed as paronychia or digital mucous cysts. They occur not only on the palms and soles but also on the lateral aspects and tips of the fingers and toes. We report a rare case of deep palmoplantar wart occurring on proximal nail fold, unusual site of right 5th finger in an 11-year-old girl.
Child ; Female ; Fingers ; Humans ; Paronychia ; Toes ; Warts*

No abstract available.
Epidermal Cyst

No abstract available.
Herpes Zoster* ; Intestinal Pseudo-Obstruction*

BACKGROUND: Sporotrichosis is a chronic, deep cutaneous fungal infection characterized by nodular lesions of the cutaneous and subcutaneous tissues with involvement of the adjacent lymphatics. The infection is usually acquired by the traumatic implantation of the dimorphic fungus Sporothrix schenckii onto the skin. The incidence and cilnical features, treatment methods of sporotrichosis have been changed with time. OBJECTIVE: The purpose of this study is to describe the changes of the clinical features, diagnostic and treatment methods in sporotrichosis. METHODS: The observation of 45 patients with sporotrichosis who had visited the Department of Dermatology, Chonbuk National University Hospital for 18 years. All samples of formalin-fixed, paraffin- embedded skin tissue were stained with anti-BCG immunohistochemical stain and PAS stain. RESULTS: Forty-five cases of sporotrichosis were included. In the eighties, the first half (1982~1990), there were 28 cases (62%) of sporotrichosis, and there were 17 cases (38%) in the nineties, the second half (1991~1999). The age was varied from 4 to 82 years averaging 46 years and the sites of predilection were upper extremities (56%) and then the face (33%). The 64% of the total cases was lymphocutaneous type, and the rest was fixed cutaneous type. In the first half of the period the 32% was fixed cutaneous type, and in the second half of the period the 41% was fixed cutaneous type. The 42% of total cases was positive with PAS stain, and the 62% was positive with anti-BCG stain. In the treatment of sporotrichosis, potassium iodide (KI) was the choice of treatment in the first half of the period, however itraconazole is gradually used in the second half of the period. CONCLUSION: According to this study, some changes in clinical findings and treatment methods of sporotrichosis were noted. Anti-BCG stain can be the useful screening method.
Dermatology ; Fungi ; Humans ; Incidence ; Itraconazole ; Jeollabuk-do ; Mass Screening ; Potassium Iodide ; Skin ; Sporothrix ; Sporotrichosis* ; Subcutaneous Tissue ; Upper Extremity

We report a case of a tick bite by Ixodes nipponensis found on the neck of a 75-year-old female. The tick was thought to be in the lesion for 10 days. Till now 31 cases of tick bites were reported in Korea including the present case. The review of the Korean cases revealed that the ratio of female/male was 1.3 : 1, its age distribution was from 1st to 8th decade, sites of the invasion were trunk, head and neck, extremities, and anogenital area in order of frequency. Its prevalent season was spring and summer and the most common species(17/31) was Ixodes nipponensis.
Age Distribution ; Aged ; Extremities ; Female ; Head ; Humans ; Ixodes ; Korea ; Neck ; Seasons ; Tick Bites* ; Ticks*